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Article
Erratum to: Quantification of micafungin in human plasma by liquid chromatography-tandem mass spectrometry
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Article
Quantification of micafungin in human plasma by liquid chromatography-tandem mass spectrometry
Micafungin (MCF) is an antifungal agent of the echinocandin class approved in Europe both in adults and in children for the treatment of invasive candidiasis. Few analytical methods for therapeutic drug monito...
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Chapter
Infectious Complications of Antineoplastic Chemotherapy in Children with Acute Leukemia or Solid Tumors
Infections represent important complications during chemotherapy for pediatric malignancies. The incidence of infections varies according to the type of underlying disease, being higher in children with acute ...
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Article
Near-miss events are really missed! Reflections on incident reporting in a department of pediatric surgery
The aim of this study was to evaluate the frequency of surgical and organizational events that occurred in the whole Department of Paediatric Surgery at Gaslini Children’s Hospital through an incident-reportin...
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Article
Clostridium difficile-associated disease in children with solid tumors
The goal of this study was to describe the incidence of Clostridium difficile-associated disease (CDAD) in children with solid tumours.
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Article
Open AccessSafety and efficacy of a caspofungin-based combination therapy for treatment of proven or probable aspergillosis in pediatric hematological patients
Fungal infections are diagnosed increasingly often in patients affected by hematological diseases and their mortality has remained high. The recent development of new antifungal drugs gives the clinician the p...
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Article
Correlation between “malfunctioning events” and catheter-related infections in pediatric cancer patients bearing tunneled indwelling central venous catheter: results of a prospective observational study
To evaluate the possible link between malfunctioning events and catheter related infections in indwelling central venous devices in children with cancer.
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Article
Urokinase for restoring patency of malfunctioning or blocked central venous catheters in children with hemato-oncological diseases
To evaluate differences in success rate between two dosages of intraluminal urokinase (IL-UK) for treatment of withdraw occlusion in central venous catheters (CVC) and to confirm the efficacy of a salvage prot...
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Article
A single institution observational study of early mechanical complications in central venous catheters (valved and open-ended) in children with cancer
The use of indwelling central venous catheters (CVCs) has become essential for managing children undergoing cancer treatment. Various types of CVCs are available, but reports on complications observed in pedia...
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Article
The role of heparin prophylaxis and Doppler ultrasound examination in preventing and diagnosing central venous catheter related complications
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Article
Cotrimoxazole prophylaxis of Pneumocystis carinii infection during the treatment of childhood acute lymphoblastic leukemia – beware non compliance in older children and adolescents
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Article
The desire to be fashionable. Should we consider it a risk factor for infection in adolescents with acute leukaemia?
Three cases of skin infection, two with Pseudomonas aeruginosa and one with Staphylococcus aureus in three adolescents with acute leukaemia are described. In all cases the infection was clearly related to the la...
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Chapter
Factors predisposing cancer patients to infection
As a consequence of major advances in medicine in the last few decades, patients with illnesses previously considered untreatable may now receive appropriate treatment and survive. Unfortunately, this progress...