51 Result(s)
within
Christian D. Mallen
-
Article
Open AccessMultisite pain and self-reported falls in older people: systematic review and meta-analysis
Multisite pain and falls are common in older people, and isolated studies have identified multisite pain as a potential falls risk factor. This study aims to synthesise published literature to further explore ...
-
Article
Open AccessSupport available for and perceived priorities of people with polymyalgia rheumatica and giant cell arteritis: results of the PMRGCAuk members’ survey 2017
Polymyalgia rheumatica and giant cell arteritis are relatively common, but under research inflammatory rheumatological conditions. This survey aimed to ascertain the matters in which patients feel they need su...
-
Article
Open AccessRisk of chronic kidney disease in patients with gout and the impact of urate lowering therapy: a population-based cohort study
An association between gout and renal disease is well-recognised but few studies have examined whether gout is a risk factor for subsequent chronic kidney disease (CKD). Additionally, the impact of urate-lower...
-
Article
Open AccessObesity, hypertension and diuretic use as risk factors for incident gout: a systematic review and meta-analysis of cohort studies
Gout treatment remains suboptimal. Identifying populations at risk of develo** gout may provide opportunities for prevention. Our aim was to assess the risk of incident gout associated with obesity, hyperten...
-
Article
How common is depression in patients with polymyalgia rheumatica?
Depression is common in inflammatory disorders such as rheumatoid arthritis and systemic lupus erythematosus and negatively impacts on outcomes. Given the long-term nature of polymyalgia rheumatica (PMR) and its ...
-
Article
Open AccessDiagnostic delay for giant cell arteritis – a systematic review and meta-analysis
Giant cell arteritis (GCA), if untreated, can lead to blindness and stroke. The study’s objectives were to (1) determine a new evidence-based benchmark of the extent of diagnostic delay for GCA and (2) examine...
-
Article
Open AccessThe pathway to consultation for rheumatoid arthritis: exploring anticipated actions between the onset of symptoms and face-to-face encounter with a healthcare professional
When people first experience symptoms of rheumatoid arthritis (RA) they often delay seeking medical attention resulting in delayed diagnosis and treatment. This research assesses behaviours people might engage...
-
Article
Open AccessVariation in GP decisions on antihypertensive treatment in oldest-old and frail individuals across 29 countries
In oldest-old patients (>80), few trials showed efficacy of treating hypertension and they included mostly the healthiest elderly. The resulting lack of knowledge has led to inconsistent guidelines, mainly bas...
-
Article
Open AccessPrognosis research ideally should measure time-varying predictors at their intended moment of use
Prognosis research studies (e.g. those deriving prognostic models or examining potential predictors of outcome) often collect information on time-varying predictors after their intended moment of use, sometimes u...
-
Article
Prevalence of cardiovascular-related comorbidity in ankylosing spondylitis, psoriatic arthritis and psoriasis in primary care: a matched retrospective cohort study
The aim of this study is to compare the prevalence of cardiovascular (CVD)-related comorbidities in patients with ankylosing spondylitis (AS), psoriatic arthritis (PsA) or psoriasis (Ps) in UK primary care aga...
-
Article
Open AccessIllness perceptions of gout patients and the use of allopurinol in primary care: baseline findings from a prospective cohort study
Patients’ perceptions of their illness are dynamic and can directly influence aspects of management. Our aim was to examine the illness perceptions of gout patients in UK primary care and associations with all...
-
Article
Open AccessCharacterising those with incident polymyalgia rheumatica in primary care: results from the PMR Cohort Study
The aim was to characterise the sociodemographic, general health and polymyalgia rheumatica (PMR)-specific features of participants in a large inception cohort of patients with PMR diagnosed in UK primary care.
-
Article
Open AccessProceedings of the First International Conference on Stepped Wedge Trial Design
I1 Introduction
-
Article
Open AccessA joint effort over a period of time: factors affecting use of urate-lowering therapy for long-term treatment of gout
Although international guidelines encourage urate lowering therapy (ULT) for people who have more than two attacks of gout, only 30 % of patients are prescribed it and only 40 % of those adhere to the treatmen...
-
Article
Open Access“You want to get on with the rest of your life”: a qualitative study of health-related quality of life in gout
The objective of the study is to examine the impact of gout and its treatments on health-related quality of life (HRQOL) using focus group interviews. From the baseline phase of a cohort study of HRQOL in gout...
-
Article
Open Access“Why me? I don’t fit the mould … I am a freak of nature”: a qualitative study of women’s experience of gout
Gout is more common in men, and is often perceived by both patients and health practitioners to be a disorder of men, but its prevalence in women is increasing. Little is known about women’s experience of gout...
-
Article
Open AccessFoot problems in people with gout in primary care: baseline findings from a prospective cohort study
Foot problems are common in people with gout yet the prevalence of current foot problems in people with gout and the burden they present to healthcare systems is not known. This cross-sectional study aimed to ...
-
Article
Open AccessGout and risk of chronic kidney disease and nephrolithiasis: meta-analysis of observational studies
To determine the prevalence of chronic kidney disease and nephrolithiasis in people with gout, and the association between gout and prevalent or incident chronic kidney disease and nephrolithiasis.
-
Article
Open AccessThe Ariadne principles: how to handle multimorbidity in primary care consultations
Multimorbidity is a health issue mostly dealt with in primary care practice. As a result of their generalist and patient-centered approach, long-lasting relationships with patients, and responsibility for cont...
-
Article
Open AccessRepeated primary care consultations for non-specific physical symptoms in children in UK: a cohort study
Non-specific physical symptoms (NSPS), such as headache and abdominal pain, are common reasons for children to consult primary care. NSPS represent a significant burden not only on society, but also on health ...
