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Open AccessLignocellulose-based analytical devices: bamboo as an analytical platform for chemical detection
This article describes the development of lignocellulose-based analytical devices (LADs) for rapid bioanalysis in low-resource settings. LADs are constructed using either a single lignocellulose or a hybrid de...
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Article
Screen Printed Paper-based Diagnostic Devices with Polymeric Inks
A simple and low-cost fabrication method for paper-based diagnostic devices (PBDDs) is described in this study. Street-available polymer solutions were screen printed onto filter papers to create hydrophobic p...
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Article
Open AccessCotton-based Diagnostic Devices
A good diagnostic procedure avoids wasting medical resources, is easy to use, resists contamination and provides accurate information quickly to allow for rapid follow-up therapies. We developed a novel diagno...
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Article
Paper-based immunoaffinity devices for accessible isolation and characterization of extracellular vesicles
We present a paper-based immunoaffinity platform for separating subsets of extracellular vesicles (EVs). This method is inexpensive, robust, easy-to-use (easy-to-prepare), and compatible with downstream analy...
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Article
Paper-based diagnostic devices for evaluating the quality of human sperm
Male infertility, which amounts to half of all infertility cases, is a serious problem worldwide. The percentage of fertility-related patients in sub-Saharan African countries is higher than that for the devel...
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Open AccessMechanical stretch and shear flow induced reorganization and recruitment of fibronectin in fibroblasts
It was our objective to study the role of mechanical stimulation on fibronectin (FN) reorganization and recruitment by exposing fibroblasts to shear fluid flow and equibiaxial stretch. Mechanical stimulation w...
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Open Accessβ-Lapachone induces heart morphogenetic and functional defects by promoting the death of erythrocytes and the endocardium in zebrafish embryos
β-Lapachone has antitumor and wound healing-promoting activities. To address the potential influences of various chemicals on heart development of zebrafish embryos, we previously treated zebrafish embryos wit...
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Maskless fabrication of small-scale structures through controlling phase interactions
We present a technique to create three-dimensional (3-D) microstructures using optical phase interactions with photocuring chemistry. We formulated a photocurable poly(dimethylsiloxane) (photoPDMS) consisting ...
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Probing Cell Structure Responses Through a Shear and Stretching Mechanical Stimulation Technique
Cells are complex, dynamic systems that respond to various in vivo stimuli including chemical, mechanical, and scaffolding alterations. The influence of mechanics on cells is especially important in physiologi...
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Probing localized neural mechanotransduction through surface-modified elastomeric matrices and electrophysiology
Mechanotransduction of sensory neurons is of great interest to the scientific community, especially in areas such as pain, neurobiology, cardiovascular homeostasis and mechanobiology. We describe a method to i...
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Subfeature patterning of organic and inorganic materials using robotic assembly
The ability to create small-scale material patterns using lithography has been limited by the feature sizes and assembly of the master stam** system. Develo** a simple and robust robotically automated patt...