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Open AccessEffects of donor-specific microvascular anatomy on hemodynamic perfusion in human choriocapillaris
Evidence from histopathology and clinical imaging suggest that choroidal anatomy and hemodynamic perfusion are among the earliest changes in retinal diseases such as age-related macular degeneration (AMD). How...
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Open AccessA comparative study of clinicopathological and imaging features of HBV-negative and HBV-positive intrahepatic cholangiocarcinoma patients with different pathologic differentiation degrees
Hepatitis B is a risk factor for the development of intrahepatic cholangiocarcinoma. The prognosis of HBV-related ICC remains to be further investigated. To investigate the clinical, pathological and imaging f...
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Open AccessVH-CH1 switch region-inserting multispecific antibody designs and their efficacy against SARS-CoV-2 in vitro and in vivo
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Open AccessAI-assisted accelerated MRI of the ankle: clinical practice assessment
High-spatial resolution magnetic resonance imaging (MRI) is essential for imaging ankle joints. However, the clinical application of fast spin-echo sequences remains limited by their lengthy acquisition time. ...
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Article
Open AccessCity-scale Vehicle Trajectory Data from Traffic Camera Videos
Vehicle trajectory data underpins various applications in intelligent transportation systems, such as traffic surveillance, traffic prediction, and traffic control. Traditional vehicle trajectory datasets, rec...
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Open AccessA case of Vagococcus fluvialis isolated from the bile of a patient with calculous cholecystitis
Chronic cholecystitis, characterized by persistent inflammation of the gallbladder, predominantly stems from the prolonged presence of gallstones. Calculous cholecystitis has demonstrated a consistent escalati...
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Open AccessJoint analysis of the metabolomics and transcriptomics uncovers the dysregulated network and develops the diagnostic model of high-risk neuroblastoma
High-risk neuroblastoma (HR-NB) has a significantly lower survival rate compared to low- and intermediate-risk NB (LIR-NB) due to the lack of risk classification diagnostic models and effective therapeutic tar...
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Open AccessValidity of fractional exhaled nitric oxide and small airway lung function measured by IOS in the diagnosis of cough variant asthma in preschool children with chronic cough
To investigate the role of combined impulse oscillometry (IOS) and fractional exhaled nitric oxide (FeNO) in the diagnosis of cough variant asthma (CVA) in preschool children.
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Open AccessCorrection: Gamabufotalin, a bufadienolide compound from toad venom, suppresses COX-2 expression through targeting IKKβ/NF-κB signaling pathway in lung cancer cells
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Open AccessLINC02159 promotes non-small cell lung cancer progression via ALYREF/YAP1 signaling
Lung cancer is the leading cause of cancer-related deaths worldwide. Long non-coding RNAs (lncRNAs) have emerged as key regulators of cancer development and progression, and as promising biomarkers for the dia...
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Open AccessOcellatuspyrones A‒G, new antibacterial polypropionates from the Chinese mollusk Placobranchus ocellatus
Marine invertebrates serve as rich sources of secondary metabolites with intriguing chemical diversities and a wide spectrum of biological activities. Particularly, marine shell-less sacoglossan mollusks have ...
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Open AccessDiversity, community structure, and quantity of eukaryotic phytoplankton revealed using 18S rRNA and plastid 16S rRNA genes and pigment markers: a case study of the Pearl River Estuary
Understanding consistencies and discrepancies in characterizing diversity and quantity of phytoplankton is essential for better modeling ecosystem change. In this study, eukaryotic phytoplankton in the Pearl R...
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Open AccessSALL4 promotes angiogenesis in gastric cancer by regulating VEGF expression and targeting SALL4/VEGF pathway inhibits cancer progression
Spalt-like protein 4 (SALL4) is a stemness-related transcription factor whose abnormal re-expression contributes to cancer initiation and progression. However, the role of SALL4 in cancer angiogenesis remains ...
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Open AccessAuthor Correction: Transcription tuned by S-nitrosylation underlies a mechanism for Staphylococcus aureus to circumvent vancomycin killing
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Open AccessEvolution of carbapenem resistance in klebsiella pneumoniae and escherichia coli carrying blaNDM−1 gene: imipenem exposure results in sustained resistance memory of strains in vitro
Antibiotics exert an outstanding selective pressure on bacteria, forcing their chromosomal gene mutations and drug resistance genes to spread. The objective of this study is to evaluate the expression of the N...
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Article
Emission Reduction Tournament Would Postpone Carbon Peaking in China
The mitigation of climate change is one of the most serious issues in global public governance. To address the climate crisis, Chinese government has proposed a clear target of carbon peaking and carbon neutra...
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Open AccessA computational method for cell type-specific expression quantitative trait loci map** using bulk RNA-seq data
Map** cell type-specific gene expression quantitative trait loci (ct-eQTLs) is a powerful way to investigate the genetic basis of complex traits. A popular method for ct-eQTL map** is to assess the interac...
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Open AccessBringing the Nature Futures Framework to life: creating a set of illustrative narratives of nature futures
To halt further destruction of the biosphere, most people and societies around the globe need to transform their relationships with nature. The internationally agreed vision under the Convention of Biological ...
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Open AccessOne Case of Epstein–Barr Virus Encephalitis from Pediatric Crohn’s Disease After 6-Mercaptopurine and Infliximab Treatment
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Open AccessTranscription tuned by S-nitrosylation underlies a mechanism for Staphylococcus aureus to circumvent vancomycin killing
Treatment of Staphylococcus aureus infections is a constant challenge due to emerging resistance to vancomycin, a last-resort drug. S-nitrosylation, the covalent attachment of a nitric oxide (NO) group to a cyste...
