81 Result(s)

Article

Repair of bone defects with prefabricated vascularized bone grafts and double-labeled bone marrow-derived mesenchymal stem cells in a rat model

This study aims to investigate the repair of bone defects with prefabricated vascularized bone grafts and double-labeled bone marrow-derived mesenchymal stem cells (BMSCs) in a rat model. BMSCs were separated ...

**ao-Rui Jiang, Hui-Ying Yang, **n-**n Zhang, Guo-Dong Lin… in Scientific Reports (2017)

Article

VHL deficiency augments anthracycline sensitivity of clear cell renal cell carcinomas by down-regulating ALDH2

The von Hippel-Lindau (VHL) is deficient in ∼70% of clear-cell renal cell carcinomas (ccRCC), which contributes to the carcinogenesis and drug resistance of ccRCC. Here we show that VHL-deficient ccRCC cells p...

Yao-Hui Gao, Zhao-**a Wu, Li-Qi **e, Cai-**a Li, Yu-Qin Mao… in Nature Communications (2017)

Article

Novel chimeric transcript RRM2-c2orf48 promotes metastasis in nasopharyngeal carcinoma

Recently, chimeric transcripts have been found to be associated with the pathogenesis and poor prognosis of malignant tumors. Through our preliminary experiment, a novel chimeric transcript called chimeric tra...

** Han, Ren-Hui Chen, Fang Wang, Jia-Yi Zeng, Shi-Tong Yu… in Cell Death & Disease (2017)

Article

Baicalin administration attenuates hyperglycemia-induced malformation of cardiovascular system

In this study, the effects of Baicalin on the hyperglycemia-induced cardiovascular malformation during embryo development were investigated. Using early chick embryos, an optimal concentration of Baicalin (6 μ...

Guang Wang, Jianxin Liang, Lin-rui Gao, Zhen-peng Si… in Cell Death & Disease (2018)

Article

Hepatitis B core VLP-based mis-disordered tau vaccine elicits strong immune response and alleviates cognitive deficits and neuropathology progression in Tau.P301S mouse model of Alzheimer’s disease and frontotemporal dementia

Truncated mis-disordered tau protein plays an important role in the pathogenesis of Alzheimer’s disease (AD) and frontotemporal dementia (FTD). Tau_294–305, an epitope in the truncated tau, is essential for pathol...

Mei Ji, **-xiu **e, Dong-qun Liu, **ao-lin Yu, Yue Zhang… in Alzheimer's Research & Therapy (2018)

Article

EIF5A1 promotes trophoblast migration and invasion via ARAF-mediated activation of the integrin/ERK signaling pathway

Trophoblast dysfunction is one mechanism implicated in the etiology of recurrent miscarriage (RM). Regulation of trophoblast function, however, is complex and the mechanisms contributing to dysregulation remai...

**g Zhang, Hui-Qin Mo, Fu-Ju Tian, Wei-Hong Zeng, **ao-Rui Liu… in Cell Death & Disease (2018)

Article

DNA methylation and hydroxymethylation profiles reveal possible role of highly methylated TLR signaling on Fasciola gigantica excretory/secretory products (FgESPs) modulation of buffalo dendritic cells

Excretory/secretory products (ESPs) released by parasites influence the development and functions of host dendritic cells (DCs). However, little is known about changes of DNA (hydroxy)methylation on DC develop...

Xue-Fang Mei, Wei Shi, Yao-Yao Zhang, Bin Zhu, Yu-Rui Wang… in Parasites & Vectors (2019)

Article

PDL1 blockage increases fetal resorption and Tfr cells but does not affect Tfh/Tfr ratio and B-cell maturation during allogeneic pregnancy

A successful pregnancy requires sophisticated regulation of uterine microenvironment to guarantee the existence of semi-allogeneic conceptus without immune rejection. T follicular regulatory (Tfr) cells exert ...

Weihong Zeng, Shi Qin, Renjie Wang, Yuchen Zhang, **aoling Ma… in Cell Death & Disease (2020)

Article

A pneumonia outbreak associated with a new coronavirus of probable bat origin

Since the outbreak of severe acute respiratory syndrome (SARS) 18 years ago, a large number of SARS-related coronaviruses (SARSr-CoVs) have been discovered in their natural reservoir host, bats^1–4. Previous studi...

Peng Zhou, **ng-Lou Yang, **an-Guang Wang, Ben Hu, Lei Zhang, Wei Zhang… in Nature (2020)

Article

Comparison of epidemiological and clinical characteristics of COVID-19 patients with and without Wuhan exposure

A novel coronavirus called severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), first identified in Wuhan, China, has been rapidly spreading around the world. This study investigates the epidemiologic...

Jiang-shan Lian, Huan Cai, Shao-rui Hao, ** **… in Journal of Zhejiang University-SCIENCE B (2020)

Article

Author Correction: Repair of bone defects with prefabricated vascularized bone grafts and double-labeled bone marrow-derived mesenchymal stem cells in a rat model

An amendment to this paper has been published and can be accessed via a link at the top of the paper.

**ao-Rui Jiang, Hui-Ying Yang, **n-**n Zhang, Guo-Dong Lin… in Scientific Reports (2020)

Article

Interferon-α2b spray inhalation did not shorten virus shedding time of SARS-CoV-2 in hospitalized patients: a preliminary matched case-control study

Currently, there are no drugs that have been proven to be effective against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Because of its broad antiviral activity, interferon (IFN) should be eva...

Shao-rui Hao, Ren Yan, Shan-yan Zhang… in Journal of Zhejiang University-SCIENCE B (2020)

Article

Addendum: A pneumonia outbreak associated with a new coronavirus of probable bat origin

Peng Zhou, **ng-Lou Yang, **an-Guang Wang, Ben Hu, Lei Zhang, Wei Zhang… in Nature (2020)