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Article
Generation of genuine entanglement up to 51 superconducting qubits
Scalable generation of genuine multipartite entanglement with an increasing number of qubits is important for both fundamental interest and practical use in quantum-information technologies1,2. On the one hand, m...
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Article
Structural insights into human ABCC4-mediated transport of platelet agonist and antagonist
Human platelets contribute to hemostasis and thrombosis, the imbalance of which can cause cardiovascular diseases. The activation and accumulation of platelets can be induced by agonists or inhibited by antago...
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Article
Open AccessMeasurement of electrons from open heavy-flavor hadron decays in Au+Au collisions at \( \sqrt{s_{\textrm{NN}}} \) = 200 GeV with the STAR detector
We report a new measurement of the production of electrons from open heavy-flavor hadron decays (HFEs) at mid-rapidity (|y| < 0.7) in Au+Au collisions at ...
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Article
Open AccessS100 proteins in cardiovascular diseases
Cardiovascular diseases have become a serious threat to human health and life worldwide and have the highest fatality rate. Therefore, the prevention and treatment of cardiovascular diseases have become a focu...
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Article
Rab37 Promotes Endothelial Differentiation and Accelerates ADSC-Mediated Diabetic Wound Healing through Regulating Secretion of Hsp90α and TIMP1
Accumulating evidence indicates that adipose tissue-derived mesenchymal stem cells (ADSCs) are an effective treatment for diabetic refractory wounds. However, the application of ADSCs to diabetic wounds is sti...
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Article
Inhibiting von Hippel‒Lindau protein-mediated Dishevelled ubiquitination protects against experimental parkinsonism
Dopaminergic neuron degeneration is a hallmark of Parkinson’s disease (PD). We previously reported that the inactivation of von Hippel‒Lindau (VHL) alleviated dopaminergic neuron degeneration in a C. elegans mode...
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Article
Ambient nitrogen dioxide and cardiovascular diseases in rural regions: a time-series analyses using data from the new rural cooperative medical scheme in Fuyang, East China
Most of studies relating ambient nitrogen dioxide (NO2) exposure to hospital admissions for cardiovascular diseases (CVDs) were conducted among urban population. Whether and to what extent these results could be ...
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Chapter and Conference Paper
Research on Target Trajectory Planning Method of Humanoid Manipulators Based on Reinforcement Learning
The goal of most asymmetrically coordinated manipulative tasks of humanoid manipulators is multilevel. For example, a bottle cap screwing task is composed of several sub-objectives, such as reaching, gras**,...
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Article
Open AccessEvidence of Mass Ordering of Charm and Bottom Quark Energy Loss in Au+Au Collisions at RHIC
Partons traversing the strongly interacting medium produced in heavy-ion collisions are expected to lose energy depending on their color charge and mass. We measure the nuclear modification factors for charm- ...
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Article
Learning Degradation-Invariant Representation for Robust Real-World Person Re-Identification
Person re-identification (Re-ID) in real-world scenarios suffers from various degradations, e.g., low resolution, weak lighting, and bad weather. These degradations hinders identity feature learning and signif...
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Article
Open AccessInjectable magnetic montmorillonite colloidal gel for the postoperative treatment of hepatocellular carcinoma
Bioactive materials have been extensively developed for the adjuvant therapy of cancer. However, few materials can meet the requirements for the postoperative resection of hepatocellular carcinoma (HCC) due to...
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Article
Open AccessA novel splice site variant c.1183 + 1 G > C in DFNA5 causing autosomal dominant nonsyndromic hearing loss in a Chinese family
The most frequent clinical presentation of autosomal dominant nonsyndromic hearing loss (ADNSHL) is bilateral, symmetrical, postlingual progressive sensorineural hearing loss, which begins with impairment at h...
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Article
Open AccessDefect engineering of layered double hydroxide nanosheets as inorganic photosensitizers for NIR-III photodynamic cancer therapy
Although two-dimensional (2D) layered double hydroxides (LDHs) have been widely used as efficient nanoagents for biological diagnosis and treatment, they have been found to be inert as photosensitizers (PSs) f...
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Article
Structural basis for the gating modulation of Kv4.3 by auxiliary subunits
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Article
Open AccessDAB2IP predicts treatment response and prognosis of ESCC patients and modulates its radiosensitivity through enhancing IR-induced activation of the ASK1-JNK pathway
Disabled homolog 2 interacting protein (DAB2IP) plays a tumor-suppressive role in several types of human cancers. However, the molecular status and function of the DAB2IP gene in esophageal squamous cell carci...
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Article
Identification, purification, and pharmacological activity analysis of Desmodus rotundus salivary plasminogen activator alpha1 (DSPAα1) expressed in transgenic rabbit mammary glands
Desmodus rotundus plasminogen activator alpha 1(DSPAα1) is a thrombolytic protein with advantages, such as a long half-life, high accuracy and specificity for thrombolysis, wide therapeutic window, and no neuroto...
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Article
In-situ quantification of the surface roughness for facile fabrications of atomically smooth thin films
This work presents an in-situ technique to quantify the layer-by-layer roughness of thin films and heterostructures by measuring the spectral profile of the reflection high-energy electron diffraction (RHEED). Th...
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Article
Becker muscular dystrophy: case report, review of the literature, and analysis of differentially expressed hub genes
Becker muscular dystrophy (BMD) is a genetic and progressive neuromuscular disease caused by mutations in the dystrophin gene with no available cure. A case report and comprehensive review of BMD cases aim to ...
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Article
Mitochondrial aldehyde dehydrogenase (ALDH2) rescues cardiac contractile dysfunction in an APP/PS1 murine model of Alzheimer’s disease via inhibition of ACSL4-dependent ferroptosis
Alzheimer’s disease (AD) is associated with high incidence of cardiovascular events but the mechanism remains elusive. Our previous study reveals a tight correlation between cardiac dysfunction and low mitocho...
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Article
Open AccessCRISPR/Cas9-mediated knockout of APOC3 stabilizes plasma lipids and inhibits atherosclerosis in rabbits
High levels of apolipoprotein C3 (APOC3) can lead to hypertriglyceridemia, which increases the risk of cardiovascular disease. We aim to create APOC3-knockout (KO) rabbits and explore the effects of APOC3 dele...
