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191 Result(s)
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Article
Open AccessPredictive effect of the systemic inflammation response index (SIRI) on the efficacy and prognosis of neoadjuvant chemoradiotherapy in patients with locally advanced rectal cancer
Inflammation is a part of tumours, and inflammatory cells can affect the proliferation, invasion, and development of tumour cells. An increasing number of peripheral blood inflammatory markers have been found ...
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Open AccessTR4 worsen urosepsis by regulating GSDMD
Urosepsis is a life-threatening organ disease in which pathogenic microorganisms in the urine enter the blood through the vessels, causing an imbalance in the immune response to infection. The aim of this stud...
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Open AccessAnalysis of relevant factors influencing size of breast abscess cavity during lactation: a cross-sectional study
The aim of this study was to investigate risk factors for the severity of breast abscess during lactation.
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Open AccessPrognostic significance of liver stiffness in patients with primary biliary cholangitis: validation of Baveno VII criteria
The role of liver stiffness measurements (LSM) in patients with primary biliary cholangitis (PBC) remains to be further elucidated.
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Open AccessMean compression ratio of a self-expandable valve is associated with the need for pacemaker implantation after transcatheter aortic valve replacement
The risk and timing of permanent pacemaker implantation (PPMI) after transcatheter aortic valve replacement (TAVR) is still hard to predict. We aimed to analyze the relationship between the compression ratio o...
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Open AccessMultidisciplinary prehabilitation to improve frailty and functional capacity in high-risk elective surgical patients: a retrospective pilot study
Frailty is associated with worse outcomes and higher healthcare costs. The long waiting time for surgery is a potential ‘teachable’ moment. We examined the feasibility and safety of a pilot prehabilitation pro...
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Open AccessIdentification of potential crucial genes and therapeutic targets for epilepsy
Epilepsy, a central neurological disorder, has a complex genetic architecture. There is some evidence suggesting that genetic factors play a role in both the occurrence of epilepsy and its treatment. However, ...
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Open AccessCurrent progression in application of extracellular vesicles in central nervous system diseases
Early diagnosis and pharmacological treatment of central nervous system (CNS) diseases has been a long-standing challenge for clinical research due to the presence of the blood–brain barrier. Specific proteins...
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Open AccessEfficacy of various surgical approaches in treating hematospermia using transurethral seminal vesiculoscopy
To explore the efficacy of different approaches of seminal vesiculoscopy surgery and the predictive factors of good treatment outcome.
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Open AccessUbiquitin-conjugating enzyme E2C (UBE2C) is a prognostic indicator for cholangiocarcinoma
Cholangiocarcinoma is the most common malignant bile duct tumor in Southeast Asia. The special location of cholangiocarcinoma leads to it being difficult to diagnose. Currently, the progress in clinical progno...
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Open AccessCombined utility of Ki-67 index and tumor grade to stratify patients with pancreatic ductal adenocarcinoma who underwent upfront surgery
To investigate the prognostic prediction of a new indicator, combined by tumor grade and Ki-67, in patients with resected pancreatic ductal adenocarcinoma (PDAC).
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Open AccessSNAP25 is a potential target for early stage Alzheimer’s disease and Parkinson’s disease
Alzheimer’s disease (AD) and Parkinson’s disease (PD), two common irreversible neurodegenerative diseases, share similar early stage syndromes, such as olfaction dysfunction. Yet, the potential comorbidity mec...
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Open AccessHeterogeneity and Adjuvant Therapeutic Approaches in MSI-H/dMMR Resectable Gastric Cancer: Emerging Trends in Immunotherapy
Gastric cancer (GC) remains one of the world’s most common and fatal malignant tumors. With a refined understanding of molecular ty** in recent years, microsatellite instability (MSI) has become a major mole...
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Open AccessComparison of anal function and quality of life after conformal sphincter preservation operation and intersphincteric resection of very low rectal cancer: a multicenter, retrospective, case–control analysis
Conformal sphincter preservation operation (CSPO) is a sphincter preservation operation for very low rectal cancers. Compared to intersphincteric resection (ISR), CSPO retains more dentate line and distal rect...
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Open AccessHigher plasma aldosterone concentrations in patients with aortic diseases and hypertension: a retrospective observational study
Aortic diseases remain a highly perilous macrovascular condition. The relationship between circulating aldosterone and aortic diseases is rarely explored, thus we investigated the difference in plasma aldoster...
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Open AccessComparative study on the clinical efficacy of small plate assisted anatomic plate and traditional double plate in the treatment of Rüedi and Allgöwer II - III pilon fracture
The aim of this study was to investigate the clinical efficacy of small plate assisted anatomical plate and traditional double plate in the treatment of Rüedi and Allgöwer II - III pilon fracture.
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Open AccessMechanisms and biomarkers of immune-related adverse events in gastric cancer
Immune-checkpoint inhibitors (ICIs), different from traditional cancer treatment models, have shown unprecedented anti-tumor effects in the past decade, greatly improving the prognosis of many malignant tumors...
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Open AccessA review on recent advances on nobiletin in central and peripheral nervous system diseases
In recent years, the role of nobiletin in neuronal disorders has received extensive attention. However, the study of nobiletin in the peripheral nervous system is limited. Nobiletin, as a compound with high fa...
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ASO Video Abstract: Neoadjuvant Chemo-Immunotherapy Increases Tumor Immune Lymphocytes Infiltration in Resectable NSCLC
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Open AccessLymphangiogenesis in gastric cancer: function and mechanism
Increased lymphangiogenesis and lymph node (LN) metastasis are thought to be important steps in cancer metastasis, and are associated with patient's poor prognosis. There is increasing evidence that the lympha...