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  1. Article

    Open Access

    Predictive effect of the systemic inflammation response index (SIRI) on the efficacy and prognosis of neoadjuvant chemoradiotherapy in patients with locally advanced rectal cancer

    Inflammation is a part of tumours, and inflammatory cells can affect the proliferation, invasion, and development of tumour cells. An increasing number of peripheral blood inflammatory markers have been found ...

    Yuanyi Ding, Zining Liu, **g Li, Wenbo Niu, Chenhui Li, Bin Yu in BMC Surgery (2024)

  2. Article

    Open Access

    TR4 worsen urosepsis by regulating GSDMD

    Urosepsis is a life-threatening organ disease in which pathogenic microorganisms in the urine enter the blood through the vessels, causing an imbalance in the immune response to infection. The aim of this stud...

    Huan Wang, Shibin Zhu, Zhenwei Zhou, Zhenghui Wang in European Journal of Medical Research (2024)

  3. Article

    Open Access

    Analysis of relevant factors influencing size of breast abscess cavity during lactation: a cross-sectional study

    The aim of this study was to investigate risk factors for the severity of breast abscess during lactation.

    Gao Yajun, Zou Yan, Zhang Yi, Chen si, Li yan in European Journal of Medical Research (2024)

  4. Article

    Open Access

    Prognostic significance of liver stiffness in patients with primary biliary cholangitis: validation of Baveno VII criteria

    The role of liver stiffness measurements (LSM) in patients with primary biliary cholangitis (PBC) remains to be further elucidated.

    Dawei Ding, Guanya Guo, Lina Cui, Gui Jia, **ufang Wang in Hepatology International (2024)

  5. Article

    Open Access

    Mean compression ratio of a self-expandable valve is associated with the need for pacemaker implantation after transcatheter aortic valve replacement

    The risk and timing of permanent pacemaker implantation (PPMI) after transcatheter aortic valve replacement (TAVR) is still hard to predict. We aimed to analyze the relationship between the compression ratio o...

    Yiming Qi, Yuefan Ding, Wenzhi Pan, **aochun Zhang in European Journal of Medical Research (2024)

  6. Article

    Open Access

    Multidisciplinary prehabilitation to improve frailty and functional capacity in high-risk elective surgical patients: a retrospective pilot study

    Frailty is associated with worse outcomes and higher healthcare costs. The long waiting time for surgery is a potential ‘teachable’ moment. We examined the feasibility and safety of a pilot prehabilitation pro...

    Henry Man Kin Wong, Ding Qi, Bosco Hon Ming Ma, Pik Yi Hou in Perioperative Medicine (2024)

  7. Article

    Open Access

    Identification of potential crucial genes and therapeutic targets for epilepsy

    Epilepsy, a central neurological disorder, has a complex genetic architecture. There is some evidence suggesting that genetic factors play a role in both the occurrence of epilepsy and its treatment. However, ...

    Shitao Wang, Zhenrong **e, Tian Jun, Xuelu Ma in European Journal of Medical Research (2024)

  8. Article

    Open Access

    Current progression in application of extracellular vesicles in central nervous system diseases

    Early diagnosis and pharmacological treatment of central nervous system (CNS) diseases has been a long-standing challenge for clinical research due to the presence of the blood–brain barrier. Specific proteins...

    **ang-Min Zhang, Jie Huang, **ao-Ying Ni in European Journal of Medical Research (2024)

  9. Article

    Open Access

    Efficacy of various surgical approaches in treating hematospermia using transurethral seminal vesiculoscopy

    To explore the efficacy of different approaches of seminal vesiculoscopy surgery and the predictive factors of good treatment outcome.

    Rui-Jie Yao, Hong **ao, Shu-Shen Chen, Zhi-Hao Feng, Yi-Lang Ding, ** Chen in BMC Surgery (2023)

  10. Article

    Open Access

    Ubiquitin-conjugating enzyme E2C (UBE2C) is a prognostic indicator for cholangiocarcinoma

    Cholangiocarcinoma is the most common malignant bile duct tumor in Southeast Asia. The special location of cholangiocarcinoma leads to it being difficult to diagnose. Currently, the progress in clinical progno...

    Khaa Hoo Ong, Hong-Yue Lai, Ding-** Sun in European Journal of Medical Research (2023)

  11. Article

    Open Access

    Combined utility of Ki-67 index and tumor grade to stratify patients with pancreatic ductal adenocarcinoma who underwent upfront surgery

    To investigate the prognostic prediction of a new indicator, combined by tumor grade and Ki-67, in patients with resected pancreatic ductal adenocarcinoma (PDAC).

    Bo Li, **aoyi Yin, **uwen Ding, Guoxiao Zhang, Hui Jiang, Cuimin Chen in BMC Surgery (2023)

  12. Article

    Open Access

    SNAP25 is a potential target for early stage Alzheimer’s disease and Parkinson’s disease

    Alzheimer’s disease (AD) and Parkinson’s disease (PD), two common irreversible neurodegenerative diseases, share similar early stage syndromes, such as olfaction dysfunction. Yet, the potential comorbidity mec...

    Qian Wang, Sijue Tao, Lei **ng, Jiuyu Liu in European Journal of Medical Research (2023)

  13. Article

    Open Access

    Heterogeneity and Adjuvant Therapeutic Approaches in MSI-H/dMMR Resectable Gastric Cancer: Emerging Trends in Immunotherapy

    Gastric cancer (GC) remains one of the world’s most common and fatal malignant tumors. With a refined understanding of molecular ty** in recent years, microsatellite instability (MSI) has become a major mole...

    Hui Wu MSc, Wenyuan Ma BSc, Congfa Jiang MD, Ning Li MD in Annals of Surgical Oncology (2023)

  14. Article

    Open Access

    Comparison of anal function and quality of life after conformal sphincter preservation operation and intersphincteric resection of very low rectal cancer: a multicenter, retrospective, case–control analysis

    Conformal sphincter preservation operation (CSPO) is a sphincter preservation operation for very low rectal cancers. Compared to intersphincteric resection (ISR), CSPO retains more dentate line and distal rect...

    G. Sun, Y. Zang, H. Ding, Y. Chen, D. Groothof, H. Gong in Techniques in Coloproctology (2023)

  15. Article

    Open Access

    Higher plasma aldosterone concentrations in patients with aortic diseases and hypertension: a retrospective observational study

    Aortic diseases remain a highly perilous macrovascular condition. The relationship between circulating aldosterone and aortic diseases is rarely explored, thus we investigated the difference in plasma aldoster...

    Yuting Pu, Guifang Yang, **aogao Pan, Yang Zhou in European Journal of Medical Research (2023)

  16. Article

    Open Access

    Comparative study on the clinical efficacy of small plate assisted anatomic plate and traditional double plate in the treatment of Rüedi and Allgöwer II - III pilon fracture

    The aim of this study was to investigate the clinical efficacy of small plate assisted anatomical plate and traditional double plate in the treatment of Rüedi and Allgöwer II - III pilon fracture.

    Wenbin Ding, Jianing Xu, Ya Zhu, Shensheng Nian, Yifeng Lu, Miaomiao Zheng in BMC Surgery (2023)

  17. Article

    Open Access

    Mechanisms and biomarkers of immune-related adverse events in gastric cancer

    Immune-checkpoint inhibitors (ICIs), different from traditional cancer treatment models, have shown unprecedented anti-tumor effects in the past decade, greatly improving the prognosis of many malignant tumors...

    **’an Ding, Pengpeng Liu, Lingjiao Meng, Qun Zhao in European Journal of Medical Research (2023)

  18. Article

    Open Access

    A review on recent advances on nobiletin in central and peripheral nervous system diseases

    In recent years, the role of nobiletin in neuronal disorders has received extensive attention. However, the study of nobiletin in the peripheral nervous system is limited. Nobiletin, as a compound with high fa...

    Yueshan Pang, Juan **ong, You Wu, Weijun Ding in European Journal of Medical Research (2023)

  19. Article

    ASO Video Abstract: Neoadjuvant Chemo-Immunotherapy Increases Tumor Immune Lymphocytes Infiltration in Resectable NSCLC

    Tianxiang Chen MD, Zhengqi Cao MD, Yingjia Sun MD in Annals of Surgical Oncology (2023)

  20. Article

    Open Access

    Lymphangiogenesis in gastric cancer: function and mechanism

    Increased lymphangiogenesis and lymph node (LN) metastasis are thought to be important steps in cancer metastasis, and are associated with patient's poor prognosis. There is increasing evidence that the lympha...

    Pengpeng Liu, **’an Ding, Chenyu Sun, Shuya Chen in European Journal of Medical Research (2023)

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