135 Result(s)
within
English
**an Qi
Chapter
Biomedicine
-
Chapter
HDL and Oxidation
In this chapter, we will focus on HDLs’ activity of inhibiting LDL oxidation and neutralizing some other oxidants. ApoA-I was known as the main antioxidant component in HDLs. The regulation of antioxidant capa...
-
Chapter
Innate Lymphoid Cells in Airway Inflammation
Airways are constantly exposed to antigens and various pathogens. Immune cells in the airways act as first line defense system against these pathogens, involving both innate and acquired immunity. There is acc...
-
Chapter
Simulation Study of Breast Cancer Lipid Changes Affecting Membrane Oxygen Permeability: Effects of Chain Length and Cholesterol
Tumor radiotherapy relies on intracellular oxygen (O2) to generate reactive species that trigger cell death, yet hypoxia is common in cancers of the breast. De novo lipid synthesis in tumors supports cell prolife...
-
Chapter
Par-4-Dependent Apoptosis of Pancreatic Islet β Cells in Type 2 Diabetes
Pancreatic islet β-cell dysfunction is an underlying cause of type 2 diabetes. Long-term metabolic disorders lead to pancreatic islet β-cell apoptosis, which is one of the main reasons for islet β-cell dysfunc...
-
Chapter
Optogenetic Strategies for Vision Restoration
The loss of photoreceptor cells caused by retinal degenerative diseases leads to blindness. The optogenetic approach for restoring vision involves converting the surviving inner retinal neurons into photosensi...
-
Chapter
Overview of Decellularized Materials for Tissue Repair and Organ Replacement
Decellularized materials (DMs) including decellularized tissues and organs are derived from natural tissues and organs through decellularization process removing cells and other antigenic components. They keep...
-
Chapter
In Vivo Flow Cytometry
In vivo flow cytometry (IVFC) was first designed to detect circulating cells in a mouse ear. It allows real-time monitoring of cells in peripheral blood with no need to draw blood. The IVFC field has made grea...
-
Chapter
Transportome Malfunctions and the Hallmarks of Pancreatic Cancer
Ion channels and transporters (ICT) play important roles in almost all basic cellular processes. During last decades, abundant evidences have been provided that ICT (e.g., Ca2+ and K+ channels) are notable for re...
-
Chapter
Effect of Fluoride on Signal Transduction Pathways
With cytotoxicity in nature, fluoride is the essential micro-element for human body. Excessive or deficient intake would invariably cause lesions. Meanwhile, signal transduction is a highly complicated network...
-
Chapter
Mechanisms of Selective Autophagy
Autophagy is a lysosome-dependent degradation process. During autophagy, cytoplasmic components are sequestered and catabolized to supply nutrition and energy under starvation conditions. Recent work has demon...
-
Chapter
AMD Genetics: Methods and Analyses for Association, Progression, and Prediction
Age-related macular degeneration (AMD) is a multifactorial neurodegenerative disease, which is a leading cause of vision loss among the elderly in the developed countries. As one of the most successful example...
-
Chapter
Dopamine Receptors in the Gastrointestinal Tract
Dopamine (DA) regulates physiological functions through dopamine receptors (DARs), including D1, D2, D3, D4, and D5. All of the five subtypes mediate neuronal and non-neuronal functions in the central nervous sys...
-
Chapter
The Functional Properties, Physiological Roles, Channelopathy and Pharmacological Characteristics of the Slack (KCNT1) Channel
The KCNT1 gene encodes the sodium-activated potassium channel that is abundantly expressed in the central nervous system of mammalians and plays an important role in reducing neuronal excitability. Structurall...
-
Chapter
The Microenvironment of Tongue Cancer
Cancer cells interact with and remodel the surrounding microenvironment. An increasing number of studies focus on tongue tumor microenvironment (TME) to find novel approaches to investigate tongue cancer, indi...
-
Chapter and Conference Paper
Prognostic Biomarkers for Hepatocellular Carcinoma
Hepatocellular carcinoma (HCC) affects approximately half a million patients worldwide and is the most rapidly increasing cause of cancer death in the United States owing to the lack of effective treatment opt...
-
Chapter
Emerging Molecular Pharmacognosy
Molecular pharmacognosy is a science that uses molecular biology technology to study crude drugs, which refers to either fresh or simply processed products derived from plants, animals, and minerals, to be use...
-
Chapter and Conference Paper
The Application of Markov Chains in Multiplayer Online Battle Arena (MOBA) Games
The prediction of future states, be it of daily events or complex dynamical systems, has always been a challenging topic in the application of probability theory into real life. The benefit of such predictions...
-
Chapter and Conference Paper
Simulation-Based Analysis of a Network Model for Autonomous Vehicles with Vehicle-to-Vehicle Communication
Autonomous vehicle technology is an expansively researched area of transport that aims to tackle long-standing problems of traffic such as congestion, safety and efficiency. Many of these vehicles combine auto...
-
Chapter
Endoplasmic Reticulum Stress and Autophagy
In 1945, K. R. Porter et al. observed mouse embryonic fibroblasts (MEFs) and found that the cytoplasmic part of the cell had an unreported reticular structure, so it was named endoplasmic reticulum (ER). The m...
-
Chapter
Anaerobic Digestion of Microalgae Biomass for Methane Production
Biomethane is one of the most promising biofuels that is produced from a wide variety of biomass using anaerobic digestion (AD) process. Microalgae, among these biomass sources, have received significant atten...
