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Article
Open AccessLeveraging a cuproptosis-based signature to predict the prognosis and drug sensitivity of cutaneous melanoma
Immunotherapy is a vital treatment for patients with cutaneous melanoma (CM), but effective predictors to guide clinical immunotherapy are lacking. Cuproptosis is a newly discovered mode of cell death related ...
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Article
Open AccessJCBIE: a joint continual learning neural network for biomedical information extraction
Extracting knowledge from heterogeneous data sources is fundamental for the construction of structured biomedical knowledge graphs (BKGs), where entities and relations are represented as nodes and edges in the...
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Article
DPMA: a distributed profit-based placement scheme for multi-sp mobile edge computing
With the development over the past decades, mobile edge computing has been widely used in many fields. Benefit from the low latency brought by the proximity of mobile edge computing to the user side and the re...
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Article
Open AccessNeuronal Death Mechanisms and Therapeutic Strategy in Ischemic Stroke
Ischemic stroke caused by intracranial vascular occlusion has become increasingly prevalent with considerable mortality and disability, which gravely burdens the global economy. Current relatively effective cl...
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Article
Carbothermic Kinetics and Reaction Mechanism of Carbon-Containing Pellets: A Combined Treatment of Chromium-Containing Sludge and Zinc-Bearing Dust
The present work focuses on the co-processing and resource recycling of solid wastes with various valuable metallic resources generated by the steel-making process. The carbon-containing pellets were prepared ...
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Article
Open AccessIdentification and genetic diversity analysis of Rickettsia in Dermacentor nuttalli within inner Mongolia, China
The genus Rickettsia contains the lineages spotted fever group (SFG), typhus group (TG), and transitional group (TRG). The spotted fever group Rickettsia (SFGR) is transmitted by ticks. The tick species Dermacent...
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Article
Open AccessIdentification of useful genes from multiple microarrays for ulcerative colitis diagnosis based on machine learning methods
Ulcerative colitis (UC) is a chronic relapsing inflammatory bowel disease with an increasing incidence and prevalence worldwide. The diagnosis for UC mainly relies on clinical symptoms and laboratory examinati...
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Article
In vitro Scolicidal Efficacy of 5-Fluorouracil and Radiation Against Protoscoleces of Echinococcus granulosus Sensu Lato
Cystic echinococcosis (CE) caused by Echinococcus granulosus sensu lato (s.l.) is a globally distributed zoonosis. CE treatment is difficult, but radiation and 5-fluorouracil (5-FU) can be effective. However, the...
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Article
Open AccessVideo-assisted subtotal parietal pleurectomy: an effective procedure for recurrent refractory pneumothorax
Refractory pneumothorax combined with diffuse emphysematous changes is an intractable problem requiring surgical treatment. Traditional bullectomy may result in long-term air leakage and has a risk of early re...
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Article
LMNNB: Two-in-One imbalanced classification approach by combining metric learning and ensemble learning
In the real-world applications of machine learning and cybernetics, the data with imbalanced distribution of classes or skewed class proportions is very pervasive. When dealing with imbalanced data, traditiona...
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Article
Open AccessvChecker: an application-level demand-based co-scheduler for improving the performance of parallel jobs in Xen
Big data analysis requires the speedup of parallel computing. However, in the virtualized systems, the power of parallel computing is not fully exploited due to the limit of current VMM schedulers. Xen, one of...
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Article
Open AccessDNAJB8 in small extracellular vesicles promotes Oxaliplatin resistance through TP53/MDR1 pathway in colon cancer
Chemotherapy is one of the most frequently used therapies for the treatment of colon cancer (COAD). However, Oxaliplatin (L-OHP) resistance is a major obstacle to the effective treatment of COAD. Here, we inve...
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Article
Preparation of ZnO Nanoparticles from Zn-containing Rotary Hearth Furnace Dust
To solve the problem of the low added value Zn-containing rotary hearth furnace (RHF) dust, two deep eutectic solvents (DESs) were employed, such as choline chloride-urea (ChCl-urea) and choline chloride-oxali...
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Article
Regulation of prognosis-related Siglecs in the glioma microenvironment
The anti-inflammatory environment of glioma reduces the efficacy of immunotherapies. Therefore, it is vital to transform the immunosuppressive microenvironment of glioma into a pro-inflammatory environment. Si...
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Article
Changes in Dust Activity in Spring over East Asia under a Global Warming Scenario
Dust activity not only influences human health through dust storms but also affects climate at local and regional scales through the direct effects of dust aerosols on both solar and longwave radiative heating...
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Article
Open AccessCircNPHP4 in monocyte-derived small extracellular vesicles controls heterogeneous adhesion in coronary heart atherosclerotic disease
Small extracellular vesicles (sEVs)-derived circular RNAs (circRNAs) could regulate gene expression in recipient cells, and dysregulation of sEVs-derived circRNAs has been implicated in several diseases. Howev...
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Article
Rescue of maternal immune activation-induced behavioral abnormalities in adult mouse offspring by pathogen-activated maternal Treg cells
Maternal immune activation (MIA) induced by lipopolysaccharides or polyinosinic:polycytidylic acid injections can induce behavioral abnormalities in adult mouse offspring. Here, we used the soluble tachyzoite ...
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Article
Nomograms for Predicting Non-remission in Patients Who Underwent Bariatric Surgery: A Multicenter Retrospective Study in China
As a reflection of the increasing global incidence of obesity, there is a corresponding increase in the proportion of obese patients undergoing bariatric surgery. This study reviewed the factors and outcomes o...
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Article
Open AccessPreoperatively elevated RDW-SD and RDW-CV predict favorable survival in intrahepatic cholangiocarcinoma patients after curative resection
Recent studies suggest red blood cell distribution width (RDW) was a prognostic factor in various types of cancer patients, although the results are controversial. The objective of this study was to investigat...
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Article
A novel handover detection model via frequent trajectory patterns mining
As the cellular wireless communication techniques grow rapidly, the cells become smaller than the traditional communication system, then the handover events are very frequent and need to support a large number...
