139 Result(s)
within
English
Science, multidisciplinary
Miaomiao **n
Article
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Article
Open AccessUltrasound-based radiomics combined with immune status to predict sentinel lymph node metastasis in primary breast cancer
In the past few years, the axillary lymph node dissection technique has been steadily replaced by sentinel lymph node biopsy for treating and diagnosing breast cancer, thereby minimizing the complications and ...
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Open AccessPolydatin improves vascular endothelial function by maintaining mitochondrial homeostasis under high glucose conditions
Previous studies have shown that polydatin (Poly) confer cardioprotective effects. However, its underlying mechanisms remain elusive. This study showed that Poly (10 µM) treatment reversed the high glucose (HG...
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Open AccessShared metabolic shifts in endothelial cells in stroke and Alzheimer’s disease revealed by integrated analysis
Since metabolic dysregulation is a hallmark of both stroke and Alzheimer’s disease (AD), mining shared metabolic patterns in these diseases will help to identify their possible pathogenic mechanisms and potent...
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Open AccessImpacts of obesity on global subclinical left cardiac function represented by CMR-derived myocardial strain, TyG index may be a predictor
Obesity is a recognized risk factor for heart failure. People with similar weights may have different metabolic health. Notably, insulin resistance is a hallmark of obesity and a feature of heart failure. We a...
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Open AccessUltra-durable superhydrophobic cellular coatings
Develo** versatile, scalable, and durable coatings that resist the accretion of matters (liquid, vapor, and solid phases) in various operating environments is important to industrial applications, yet has pr...
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Open AccessAssociation of living environmental and occupational factors with semen quality in chinese men: a cross-sectional study
Sperm quality can be easily influenced by living environmental and occupational factors. This study aimed to discover potential semen quality related living environmental and occupational factors, expand knowl...
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Open AccessHistidine modulates amyloid-like assembly of peptide nanomaterials and confers enzyme-like activity
Amyloid-like assembly is not only associated with pathological events, but also leads to the development of novel nanomaterials with unique properties. Herein, using Fmoc diphenylalanine peptide (Fmoc–F–F) as ...
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Open AccessA polycistronic system for multiplexed and precalibrated expression of multigene pathways in fungi
Synthetic biology requires efficient systems that support the well-coordinated co-expression of multiple genes. Here, we discover a 9-bp nucleotide sequence that enables efficient polycistronic gene expression...
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Open AccessCancer-associated fibroblast-derived exosome microRNA-21 promotes angiogenesis in multiple myeloma
Multiple myeloma (MM) is the second most common hematological malignancy, and angiogenesis determines its progression. In the tumor microenvironment, normal fibroblasts (NFs) are transformed into cancer-associ...
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Open AccessSpecific mating behavior of Malayan pangolin (Manis javanica) in captivity
Pangolin is a mysterious animal in the Family Pholidota, Mammalia. Malayan pangolin (Manis javanica) is one of eight existing species and is listed in Manis. With the number of wild pangolins (Manis spp.) rapidly...
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Open AccessSmall-sample learning reveals propionylation in determining global protein homeostasis
Proteostasis is fundamental for maintaining organismal health. However, the mechanisms underlying its dynamic regulation and how its disruptions lead to diseases are largely unclear. Here, we conduct in-depth ...
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Open AccessDouble DAP-seq uncovered synergistic DNA binding of interacting bZIP transcription factors
Many eukaryotic transcription factors (TF) form homodimer or heterodimer complexes to regulate gene expression. Dimerization of BASIC LEUCINE ZIPPER (bZIP) TFs are critical for their functions, but the molecul...
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Open AccessMagnetic anchor technique assisted laparoscopic cholecystectomy in swine
Magnetic anchor device based on the principle of magnet heteropolar attraction can assist laparoscopic surgery and reduce abdominal wall trauma. This study explored the feasibility of use of our self-designed ...
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Open AccessTracheoesophageal fistula treated with magnetic compression technique in canines
There are various surgical methods for tracheoesophageal fistula; however, there is presently no unified standard. Based on the magnetic compression technique, we designed a novel method for the treatment of t...
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Open AccessTwo gates mediate NMDA receptor activity and are under subunit-specific regulation
Kinetics of NMDA receptor (NMDAR) ion channel opening and closing contribute to their unique role in synaptic signaling. Agonist binding generates free energy to open a canonical gate at the M3 helix bundle cr...
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Open AccessEffect of bedding dip angle and dynamic load on spatial variation of microscopic failure stress of shale
Physico-mechanical properties of shale are important parameters in evaluating the stability of potential wellbore and the design of hydraulic fracturing, which are primarily affected by their non-uniform spati...
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Open AccessOne dimensional wormhole corrosion in metals
Corrosion is a ubiquitous failure mode of materials. Often, the progression of localized corrosion is accompanied by the evolution of porosity in materials previously reported to be either three-dimensional or...
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Open AccessA nomogram for predicting postoperative urosepsis following retrograde intrarenal surgery in upper urinary calculi patients with negative preoperative urine culture
Retrograde intrarenal surgery (RIRS) is one of the main surgical methods for upper urinary calculi, but severe complications of infection may occur after surgery. This study aimed to establish and validate a p...
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Open AccessAn experimental study of magnetic compression technique for ureterovesical anastomosis in rabbits
This study aimed to explore the feasibility of the magnetic compression technique (MCT) for ureterovesical anastomosis in a rabbit model with ureteral obstruction. The distal ureteral obstruction model using f...
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Open AccessA comparative study of postmortem distribution and postmortem diffusion of tramadol in rabbits
In recent years, the cases of tramadol intoxication have become more frequent in many countries. However, most of the previous studies have been based on cases of tramadol intoxication, and the detailed inform...
