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190 Result(s)
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Article
Efficient degradation of cellulosic ethanol wastewater by perovskite activation of Sr element A-site doped lanthanide copper chalcogenide materials
The degradation of cellulosic ethanol wastewater by peroxymonosulfate (PMS) is one of the important methods to solve the environmental problems caused by it. In order to improve the degradation efficiency of c...
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Article
Random Access Control and Beam Management Scheme for the 5G NR based Beam Hop** LEO Satellite Communication Systems
This paper considers the scenario that the Low Earth Orbit (LEO) satellite based on Ka-band uses the agile beam to provide Internet access services for users, and studies the random access control and resource...
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Article
Glioblastomas with and without peritumoral fluid-attenuated inversion recovery (FLAIR) hyperintensity present morphological and microstructural differences on conventional MR images
Glioblastoma (GB) without peritumoral fluid-attenuated inversion recovery (FLAIR) hyperintensity is atypical and its characteristics are barely known. The aim of this study was to explore the differences in pa...
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Predicting peritumoral edema development after gamma knife radiosurgery of meningiomas using machine learning methods: a multicenter study
Edema is a complication of gamma knife radiosurgery (GKS) in meningioma patients that leads to a variety of consequences. The aim of this study is to construct radiomics-based machine learning models to predic...
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Article
LC–MS Approach to Decipher a Light Chain Chromatographic Peak Splitting of a Monoclonal Antibody
Monoclonal antibodies (mAbs), like other protein therapeutics, are prone to various forms of degradation, some of which are difficult to distinguish from the native form yet may alter potency. A generalizable ...
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Article
Open AccessThe characteristic analysis of phase-controlled array thermo-acoustic emission with multiple emitting surfaces
Thermo-acoustic (TA) ultrasound, particularly when combined with phased-controlled array technology, has garnered significant interest in the past decade due to its numerous advantages. This paper establishes ...
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Article
Erratum to: Cenozoic giant coal-bearing basin belt discovered in China’s sea area
The original online version of this article was revised: (1) Article title was changed to “Cenozoic giant coal-bearing basin belt discovered in China’s sea and its adjacent areas”; (2) title of Fig. 2 “Coal se...
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Article
Identification of LRG1 targeting peptide and its application in targeted imaging for breast cancer
Breast cancer remains a leading cause of morbidity and mortality among women worldwide, emphasizing the urgent need for enhanced diagnostic and therapeutic approaches. Leucine-rich-alpha-2-glycoprotein 1 (LRG1...
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Article
Weizmannia coagulans Extracellular Proteins Reduce Skin Acne by Inhibiting Pathogenic Bacteria and Regulating TLR2/TRAF6-Mediated NF-κB and MAPKs Signaling Pathways
As a probiotic, Weizmannia coagulans (W. coagulans) is often used in food and medicine to regulate intestinal flora and exert anti-inflammatory effects. In this study, the anti-acne efficacy and mechanism of extr...
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Article
Open AccessAnti-PD-1 antibody armored γδ T cells enhance anti-tumor efficacy in ovarian cancer
γδ T cells have the unique ability to detect a wide range of tumors with low mutation burdens, making them attractive candidates for CAR-T-cell therapy. Unlike αβ T cells and other immune cells, γδ T cells are...
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Article
Open AccessUSP1 promotes cholangiocarcinoma progression by deubiquitinating PARP1 to prevent its proteasomal degradation
Despite its involvement in various cancers, the function of the deubiquitinase USP1 (ubiquitin-specific protease 1) is unexplored in cholangiocarcinoma (CCA). In this study, we provide evidence that USP1 promo...
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Open AccessAssessment of early diabetic retinopathy severity using ultra-widefield Clarus versus conventional five-field and ultra-widefield Optos fundus imaging
To compare early diabetic retinopathy (DR) severity level and the abilities in detecting early DR lesions among conventional five-field, ultrawide-field (UWF) Optos, and UWF Clarus fundus imaging methods. This...
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Article
Distinctive metabolic remodeling in TYMP deficiency beyond mitochondrial dysfunction
Mitochondrial neurogastrointestinal encephalomyopathy (MNGIE) is caused by mutations in the TYMP gene, which encodes thymidine phosphorylase (TP). As a cytosolic metabolic enzyme, TP defects affect biological ...
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Article
A frequency error estimation for isogeometric analysis of Kirchhoff–Love cylindrical shells
A frequency error estimation is presented for the isogeometric free vibration analysis of Kirchhoff–Love cylindrical shells using both quadratic and cubic basis functions. By analyzing the discrete isogeometri...
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Article
Open AccessHSDL2 knockdown promotes the progression of cholangiocarcinoma by inhibiting ferroptosis through the P53/SLC7A11 axis
Human hydroxysteroid dehydrogenase-like 2 (HSDL2), which regulates cancer progression, is involved in lipid metabolism. However, the role of HSDL2 in cholangiocarcinoma (CCA) and the mechanism by which it regu...
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Article
The Double-edged sword effect of inclusive leadership on employee presenteeism
Prior studies commonly argued that inclusive leadership is of considerable benefit to employees but rarely discussed its potential downsides. To address this issue, this study explores why and when inclusive l...
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Article
Open AccessSSDLog: a semi-supervised dual branch model for log anomaly detection
With versatility and complexity of computer systems, warning and errors are inevitable. To effectively monitor system’s status, system logs are critical. To detect anomalies in system logs, deep learning is a ...
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Article
Open AccessProtective effects of Aureobasidium pullulans lysate on UV-damaged human skin fibroblasts and HaCaT cells
Aureobasidium pullulans (A. pullulans) has a wide range of applications. Ultraviolet (UV) rays from the sun can cause skin photoaging. In order to explore the protective effect and application potential of A. pul...
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Open AccessAnti-glioma effect of ginseng-derived exosomes-like nanoparticles by active blood–brain-barrier penetration and tumor microenvironment modulation
Inhibition of tumor growth and normalization of immune responses in the tumor microenvironment (TME) are critical issues for improving cancer therapy. However, in the treatment of glioma, effective nanomedicin...
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Open AccessChatGPT for sha** the future of dentistry: the potential of multi-modal large language model
The ChatGPT, a lite and conversational variant of Generative Pretrained Transformer 4 (GPT-4) developed by OpenAI, is one of the milestone Large Language Models (LLMs) with billions of parameters. LLMs have st...