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142 Result(s)
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Article
Open AccessTAZ2 truncation confers overactivation of p300 and cellular vulnerability to HDAC inhibition
The histone acetyltransferase p300/CBP is composed of several conserved domains, among which, the TAZ2 domain is known as a protein-protein interaction domain that binds to E1A and various transcription factor...
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Article
Boron decreases cadmium accumulation in water spinach by enhancing cadmium retention in the root cell walls
Cadmium (Cd) contamination and boron (B) deficiency are two major challenges associated with the farmland soils in Southern China. Therefore, this study was conducted to examine the impacts of B supply on Cd a...
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Article
Open AccessThe functional effects of Piezo channels in mesenchymal stem cells
Mesenchymal stem cells (MSCs) are widely used in cell therapy, tissue engineering, and regenerative medicine because of their self-renewal, pluripotency, and immunomodulatory properties. The microenvironment i...
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Open AccessAssociation between subjective well-being and all-cause mortality among older adults in China
Although several studies in high-income countries have suggested a positive association between subjective well-being (SWB) and mortality, studies conducted in low- and middle-income countries, such as China, ...
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Open AccessHyperthermophilic pretreatment composting can reduce ammonia emissions by controlling proteolytic bacterial community and the physicochemical properties
Proteolysis is the rate-limiting step in the mineralization of organic nitrogen into ammonium (NH4+) and thereby the ammonia (NH3) released during the composting. However, the dynamics of bacterial proteolytic co...
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Open AccessAssociations between vertebral bone marrow fat and sagittal spine alignment as assessed by chemical shift-encoding-based water–fat MRI
The relationship between sagittal spine alignment and vertebral bone marrow fat is unknown. We aimed to assess the relationship between vertebral bone marrow fat and sagittal spine alignment using chemical shi...
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Article
Concurrent chemoradiotherapy combined with nimotuzumab in stage III–IVa nasopharyngeal carcinoma: a retrospective analysis
The efficacy and safety of nimotuzumab (NTZ) added to concurrent chemoradiotherapy (CCRT) were investigated in patients with stage III–IVa nasopharyngeal carcinoma (NPC).
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Article
Open AccessHsa_circ_0060467 promotes breast cancer liver metastasis by complexing with eIF4A3 and sponging miR-1205
Breast cancer (BC) is the most common cancer and the top cause of female mortality worldwide. The prognosis for patients with breast cancer liver metastasis (BCLM) remains poor. Emerging studies suggest that c...
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Article
Effect of water-washing pretreatment on the enhancement of tetracycline adsorption by biogas residue biochar
Biochar preparation was a feasible strategy for realizing the reduction, harmlessness, and resource utilization of biogas residue (BR) simultaneously. How to enhance the adsorption performance of biogas residu...
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Article
Liver Transcriptome Analysis Reveals Energy Regulation and Functional Impairment of Onychostoma sima During Starvation
Releasing juvenile fish into resource-depleted waters is regarded as an effective way to restore fishery resources. However, during this stage, released fish are most vulnerable to long-term food deprivation d...
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Open AccessCorrection to: NSUN2 alleviates doxorubicin-induced myocardial injury through Nrf2-mediated antioxidant stress
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Open AccessA diagnostic model of autoimmune hepatitis in unknown liver injury based on noninvasive clinical data
All the diagnostic criteria of autoimmune hepatitis (AIH) include histopathology. However, some patients may delay getting this examination due to concerns about the risks of liver biopsy. Therefore, we aimed ...
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Article
Effectiveness of no drainage after elective day-case laparoscopic cholecystectomy, even with intraoperative gallbladder perforation: a randomized controlled trial
Laparoscopic cholecystectomy (LC) has been carried out as day-case surgery. Current guidelines do not mention the role of drainage after LC. In particular, data stay blank with no prospective study on drainage...
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Open AccessLipidomic analysis of brain and hippocampus from mice fed with high-fat diet and treated with fecal microbiota transplantation
Dietary fat intake affects brain composition and function. Different types of dietary fatty acids alter species and abundance of brain lipids in mice. The aim of this study is to explore whether the changes ar...
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Article
Open AccessNSUN2 alleviates doxorubicin-induced myocardial injury through Nrf2-mediated antioxidant stress
Doxorubicin (DOX) is a commonly used antitumor drug, but its application has been limited because of its strong cardiac damage. This study aims to explore the role of NSUN2 in DOX-induced heart injury. C57BL/6...
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Effects of temperature on the growth parameters, hepatopancreas structures, antioxidant ability, and non-specific immunity of the crayfish, Cherax destructor
Cherax destructor, a native Australian freshwater crayfish, has been extensively studied for its aquaculture potential, but its growth and immune responses at different temperatures remain unclear. In this study,...
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Open AccessDownregulation of Linc00173 increases BCL2 mRNA stability via the miR-1275/PROCA1/ZFP36L2 axis and induces acquired cisplatin resistance of lung adenocarcinoma
LINC00173 had been reported as a cisplatin (cis-diamminedichloroplatinum, DDP) chemotherapy-resistant inducer in small-cell lung cancer (SCLC) and lung squamous cell carcinoma (LUSC). This study aimed to display ...
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Article
Rapid and scalable preparation of flexible Ag nanoparticle-decorated nanocellulose SERS sensors by magnetron sputtering for trace detection of toxic materials
Cellulose-based surface-enhanced Raman scattering (SERS) platforms have attracted extensive attention as a flexible, sustainable, eco-friendly and ultrasensitive sensor for trace detection of chemical and biol...
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Open AccessDefects of microtubule cytoskeletal organization in NOA human testes
The importance of actin and microtubule (MT) cytoskeletons in testis function in rodents is known to some extent, but its role in the etiology of azoospermia in humans remains unexplored. Here, we examined if ...
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Assessment of macrobenthic community function and ecological quality after reclamation in the Changjiang (Yangtze) River Estuary wetland
An ecological optimization project (semi-closed reclamation project) was implemented to control the invasion of Spartina alterniflora, and optimize the habitat of the Chongming Dongtan wetland, in the Changjiang ...