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Metabolic Diseases
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Open AccessCharacterization of obesity-related diseases and inflammation using single cell immunophenoty** in two different diet-induced obesity models
Obesity is a growing problem worldwide and a major risk factor for many chronic diseases. The accumulation of adipose tissue leads to the release of significant amounts of pro-inflammatory cytokines and adipok...
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Neuroprotective and vasoprotective effects of herb pair of Zhiqiao-Danggui in ischemic stroke uncovered by LC-MS/MS-based metabolomics approach
Ischemic stroke is the most important cause of disability and death worldwide, but current treatments remain limited. Traditional Chinese medicine (TCM) including the herb pair of Zhiqiao-Danggui (ZD) offers a...
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Ultra-processed food consumption and risk of diabetes: results from a population-based prospective cohort
Understanding the impact of the overall construct of ultra-processed foods on diabetes risk can inform dietary approaches to diabetes prevention. In this study, we aimed to evaluate the association between ult...
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The relationship between the functional movement screen and isokinetic muscle strength around the knee in different sports
The aim of this study was to determine objective data of the relationship between the Functional Movement Screen (FMS) and isokinetic muscle strength around the knee in individuals engaged in different sports....
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Association between body mass index and semen quality: a systematic review and meta-analysis
The continuous decline of human semen quality during the past decades has drawn much concern globally. Previous studies have suggested a link between abnormal BMI and semen quality decline, but the results rem...
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Open AccessThe addition of mycoprotein to a mixed-meal impacts postprandial glucose kinetics without altering blood glucose concentrations: a randomised controlled trial
Mycoprotein is a high-fibre food previously shown to reduce postprandial glucose concentrations when ingested within a mixed-meal. We applied a dual stable isotope tracer approach to determine whether this is ...
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Open AccessInfluence of prediabetes on the prognosis of patients with myocardial infarction: a meta-analysis
Previous studies evaluating the association between prediabetes the prognosis of patients with acute myocardial infarction (AMI) showed inconsistent results. The aim of the meta-analysis was to compare the lon...
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Elucidating the therapeutic mechanism of betanin in Alzheimer’s Disease treatment through network pharmacology and bioinformatics analysis
Betanin, a natural compound with anti-inflammatory and antioxidant properties, has shown promise in mitigating Alzheimer’s disease (AD) by reducing amyloid plaque production. Employing network pharmacology, th...
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Author Correction: Micropillar arrays as a high-throughput screening platform for therapeutics in multiple sclerosis
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Open AccessDisruption of neural periodicity predicts clinical response after deep brain stimulation for obsessive-compulsive disorder
Recent advances in surgical neuromodulation have enabled chronic and continuous intracranial monitoring during everyday life. We used this opportunity to identify neural predictors of clinical state in 12 indi...
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Screening for diabetic retinopathy with artificial intelligence: a real world evaluation
Periodic screening for diabetic retinopathy (DR) is effective for preventing blindness. Artificial intelligence (AI) systems could be useful for increasing the screening of DR in diabetic patients. The aim of ...
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Hippocampal network activity forecasts epileptic seizures
Seizures in people with epilepsy were long thought to occur at random, but recent methods for seizure forecasting enable estimation of the likelihood of seizure occurrence over short horizons. These methods re...
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Elevated serum neurofilament light chain levels are associated with hepatic encephalopathy in patients with cirrhosis
Increasing evidences implicate vital role of neuronal damage in the development of hepatic encephalopathy (HE). Neurofilament light chain (NfL) is the main frame component of neurons and is closely related to ...
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Open AccessUse of diabetes technology in children
Children with type 1 diabetes and their caregivers face numerous challenges navigating the unpredictability of this complex disease. Although the burden of managing diabetes remains significant, new technology...
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An evidence-based screening tool for heart failure with preserved ejection fraction: the HFpEF-ABA score
Heart failure with preserved ejection fraction (HFpEF) is under-recognized in clinical practice. Although a previously developed risk score, termed H2FPEF, can be used to estimate HFpEF probability, this score re...
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Open AccessDoes metformin really reduce prostate cancer risk: an up-to-date comprehensive genome-wide analysis
The relationship between metformin use and prostate cancer (PCa) risk has yet to be clear despite more than a decade of debate on this topic. Hence, we aimed to investigate the causal role of metformin in redu...
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Advances in diabetes technology to improve the lives of people with cystic fibrosis
People with cystic fibrosis (CF) are at risk for dysglycaemia caused by progressive beta cell dysfunction and destruction due to pancreatic exocrine disease and fibrosis. CF-related diabetes (CFRD) is a unique...
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Open AccessThe associations between the Geriatric Nutritional Risk Index and all-cause, cancer-specific, and cardiovascular mortality in the U.S. population: a large-scale pooled survey
Previous studies have reported a close association between the Geriatric Nutritional Risk Index (GNRI) and various conditions. However, the association between the GNRI and mortality remains unclear. To examin...
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Open AccessImproving change of direction in male football players through plyometric training: a systematic review
High-intensity actions have gained increasing significance in contemporary football. Among these actions, the spotlight shines on the enhancement of change of direction (COD) speed. Several training methods ha...
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CTX-1 and TRACP-5b as biomarkers for osteoporosis risk in type 2 diabetes mellitus: a cross-sectional study
Type 2 diabetes mellitus (T2DM) demonstrates a higher risk of fractures compared to the healthy population. Therefore, the aim of our study is to assess the risk of osteoporosis in T2DM patients.
