31 Result(s)

Article

Modulation of regional nitric oxide metabolism: Blood glucose control or insulin?

Tight glycaemic control by intensive insulin therapy (IIT) reduces morbidity and mortality in critically ill patients. As potential mechanisms contributing to the clinical benefits we hypothesized that glycaem...

Björn Ellger, Lies Langouche, Milan Richir, Yves Debaveye… in Intensive Care Medicine (2008)

Article

Intensive insulin therapy: enhanced Model Predictive Control algorithm versus standard care

To investigate the effectiveness of an enhanced software Model Predictive Control (eMPC) algorithm for intravenous insulin infusion, targeted at tight glucose control in critically ill patients, over 72 h, in ...

Jeremy J. Cordingley, Dirk Vlasselaers, Natalie C. Dormand… in Intensive Care Medicine (2009)

Article

Impact of a computer-generated alert system on the quality of tight glycemic control

To assess the impact of a computer-generated blood glucose (BG) alert, generated by a Patient Data Management System (PDMS) and superimposed on a paper-based guideline, on tight glycemic control (TGC) in the i...

Geert Meyfroidt, Pieter Wouters, Wilfried De Becker… in Intensive Care Medicine (2011)

Article

Does the surface-treated AN69 membrane prolong filter survival in CRRT without anticoagulation?

The need for continuous anticoagulation remains a significant drawback in continuous renal replacement therapy (CRRT), especially in patients with increased bleeding risk. Polyethyleneimine treatment of the AN...

Miet Schetz, Sophie Van Cromphaut, Jasperina Dubois… in Intensive Care Medicine (2012)

Article

Understanding the HPA response to critical illness: novel insights with clinical implications

Eva Boonen, Greet Van den Berghe in Intensive Care Medicine (2015)

Article

Critical illness-induced dysglycemia and the brain

Dysglycemia is a characteristic feature of critical illness associated with adverse outcome. Whether dysglycemia contributes to brain dysfunction during critical illness and long-term neurological complication...

Romain Sonneville, Ilse Vanhorebeek, Heleen M. den Hertog… in Intensive Care Medicine (2015)

Article

Assessment of quadriceps muscle mass with ultrasound in critically ill patients: intra- and inter-observer agreement and sensitivity

Johan Segers, Greet Hermans, Noppawan Charususin, Tom Fivez… in Intensive Care Medicine (2015)

Article

Visualizing the pressure and time burden of intracranial hypertension in adult and paediatric traumatic brain injury

To assess the impact of the duration and intensity of episodes of increased intracranial pressure on 6-month neurological outcome in adult and paediatric traumatic brain injury.

Fabian Güiza, Bart Depreitere, Ian Piper, Giuseppe Citerio… in Intensive Care Medicine (2015)

Article

Predictive value for weakness and 1-year mortality of screening electrophysiology tests in the ICU

Muscle weakness in long-stay ICU patients contributes to 1-year mortality. Whether electrophysiological screening is an alternative diagnostic tool in unconscious/uncooperative patients remains unknown. We aim...

Greet Hermans, Helena Van Mechelen, Frans Bruyninckx… in Intensive Care Medicine (2015)

Article

Cholestatic liver (dys)function during sepsis and other critical illnesses

In ICU patients, abnormal liver tests are common. Markers of cholestasis are associated with adverse outcome. Research has focused on the possibility that mild hyperbilirubinemia, instead of indicating inadver...

Marc Jenniskens, Lies Langouche, Yoo-Mee Vanwijngaerden… in Intensive Care Medicine (2016)

Article

Blood glucose control in the ICU: don’t throw out the baby with the bathwater!

Jan Gunst, Greet Van den Berghe in Intensive Care Medicine (2016)

Article

AKIpredictor, an online prognostic calculator for acute kidney injury in adult critically ill patients: development, validation and comparison to serum neutrophil gelatinase-associated lipocalin

Early diagnosis of acute kidney injury (AKI) remains a major challenge. We developed and validated AKI prediction models in adult ICU patients and made these models available via an online prognostic calculato...

Marine Flechet, Fabian Güiza, Miet Schetz, Pieter Wouters… in Intensive Care Medicine (2017)