50 Result(s)

Article

Combined positive/negative selection for highly effective purging of PBPC grafts: towards clinical application in patients with B-CLL

Autologous PBPC transplantation is a potentially curative treatment for patients with chronic lymphocytic leukemia (CLL). As the autografts are frequently contaminated with large numbers of tumor cells, we hav...

U Paulus, N Schmitz, K Viehmann, N von Neuhoff, P Dreger in Bone Marrow Transplantation (1997)

Article

Allogeneic peripheral blood progenitor cells for treatment of relapse after bone marrow transplantation

Donor leukocyte infusions (DLI) are an effective therapy for patients who relapse with leukemia after bone marrow transplantation (BMT). Severe graft-versus-host disease and prolonged periods of pancytopenia c...

B Glass, I Majolino, P Dreger, R Scimè, A Santoro, S Vasta… in Bone Marrow Transplantation (1997)

Article

Long-term disease-free survival of patients with advanced mantle-cell lymphoma following high-dose chemotherapy

In advanced stage mantle cell lymphoma, conventional chemotherapy yields a complete remission rate below 40%, and the median survival rate is only about 3 years. Between 1991 and 1996 we treated nine such pati...

N Kröger, M Hoffknecht, P Dreger, W Krüger, W Zeller… in Bone Marrow Transplantation (1998)

Article

Comparison of different strategies of molecular genetic monitoring following autologous stem cell transplantation in patients with follicular lymphoma

Two different molecular genetic methods were compared for their suitability for monitoring minimal residual disease in patients with follicular lymphoma (FL) treated with high-dose therapy and autologous stem ...

N von Neuhoff, P Dreger, M Suttorp, M Marget, S Kell… in Bone Marrow Transplantation (1998)

Article

Autografting of highly purified peripheral blood progenitor cells following myeloablative therapy in patients with lymphoma: a prospective study of the long-term effects on tumor eradication, reconstitution of hematopoiesis and immune recovery

In a prospective study, we have investigated CD34⁺ selection of peripheral blood progenitor cells (PBPC) for autotransplantation in patients with lymphoma. Twenty-six consecutive patients (10 follicular lymphomas...

P Dreger, K Viehmann, N von Neuhoff, T Glaubitz, O Petzoldt… in Bone Marrow Transplantation (1999)

Article

Hepatitis B viremia in a patient with documented previous HBV immunity after autologous transplantation of highly purified PBSC

P Dreger, P Rautenberg, M Kneba, N Schmitz in Bone Marrow Transplantation (2000)

Article

Reduced-intensity allogeneic stem cell transplantation as salvage treatment for patients with indolent lymphoma or CLL after failure of autologous SCT

P Dreger, B Glass, B Seyfarth, A Humpe, A Claviez… in Bone Marrow Transplantation (2000)

Article

Elevated blood drug levels obtained from indwelling silicon catheters during oral cyclosporine A administration

Cyclosporine A (CsA) may be bound to and released from the inner surface of central venous catheters resulting in spuriously elevated blood drug levels. We observed this phenomenon in a boy transplanted becaus...

A Claviez, B Glass, P Dreger, M Suttorp in Bone Marrow Transplantation (2002)

Article

Enhanced antileukemic activity of allogeneic peripheral blood progenitor cell transplants following donor treatment with the combination of granulocyte colony-stimulating factor (G-CSF) and stem cell factor (SCF) in a murine transplantation model

Allogeneic peripheral blood progenitor cells (PBPCs) have mostly been mobilized by granulocyte colony-stimulating factor (G-CSF). There is neither clinical nor experimental data available addressing the questi...

G Hartung, M Zeis, B Glass, P Dreger, J Steinmann, N Schmitz… in Bone Marrow Transplantation (2003)

Article

Reduced-intensity conditioning prior to allogeneic transplantation of hematopoietic stem cells: the need for T cells early after transplantation to induce a graft-versus-lymphoma effect

In patients with poor-risk relapse of aggressive lymphoma, reduced-intensity conditioning followed by allogeneic PBSCT may have its limitations because of rapid regrowth of the tumor. We tried to address this ...

B Glass, M Nickelsen, P Dreger, A Claviez, J Hasenkamp… in Bone Marrow Transplantation (2004)

Article

Occurrence of donor-derived CLL 8 years after sibling donor SCT for CML

J B Perz, M Ritgen, M Moos, A D Ho, M Kneba, P Dreger in Bone Marrow Transplantation (2008)

Article

Pentostatin for treatment of steroid-refractory acute GVHD: a retrospective single-center analysis

Acute GVHD (aGVHD) remains a major cause of mortality in patients undergoing allo-SCT. In particular, the outcome of those patients who fail first-line therapy with glucocorticosteroids is poor. Preliminary re...

T Schmitt, T Luft, U Hegenbart, T H Tran, A D Ho, P Dreger in Bone Marrow Transplantation (2011)

Article

The EBMT activity survey: 1990–2010

A total of 654 centers from 48 countries were contacted for the 2010 survey. In all, 634 centers reported a total of 33 362 hematopoietic SCT (HSCT) with 30 012 patients receiving their first transplant (12 27...

J R Passweg, H Baldomero, A Gratwohl, M Bregni, S Cesaro… in Bone Marrow Transplantation (2012)

Article

Current status of hematopoietic cell transplantation in the treatment of systemic amyloid light-chain amyloidosis

Systemic amyloid light-chain (AL) amyloidosis is a protein conformation disorder caused by clonal plasma cell dyscrasias. Symptoms result from fibrillar extracellular deposits in various tissues. The deposits ...

S O Schönland, P Dreger, T de Witte, U Hegenbart in Bone Marrow Transplantation (2012)

Article

Prophylaxis and treatment of GVHD: EBMT–ELN working group recommendations for a standardized practice

GVHD remains the major impediment to broader application of allogeneic haematopoietic SCT. It can be prevented completely, but at the expense of other complications, rejection, relapse or delayed immune recons...

T Ruutu, A Gratwohl, T de Witte, B Afanasyev, J Apperley… in Bone Marrow Transplantation (2014)

Article

Efficacy of exercise training in SCT patients-who benefits most?

Patients undergoing allo-HCT often experience a substantial loss in physical performance. We have recently published the general effectiveness of an exercise intervention in 105 allo-HCT patients on physical p...

J Wiskemann, R Kuehl, P Dreger, R Schwerdtfeger, G Huber… in Bone Marrow Transplantation (2014)

Article

Matched unrelated donor allogeneic transplantation provides comparable long-term outcome to HLA-identical sibling transplantation in relapsed diffuse large B-cell lymphoma

The objective of this retrospective analysis was to compare outcomes of patients with diffuse large B-cell lymphoma (DLBCL) who received either a matched sibling (sib) or an unrelated donor (URD) allogeneic he...

I Avivi, C Canals, J-P Vernant, G Wulf, A Nagler, O Hermine… in Bone Marrow Transplantation (2014)