Substance Use in Older Adolescence: Overcoming the Prevention Paradox

  • Reference work entry
  • First Online:
Handbook of Substance Misuse and Addictions

Abstract

Mental disorders, including substance use disorders, frequently arise during adolescence and track into adulthood. Protracted neurodevelopment may prime adolescents toward the substance use and increase the vulnerability to harm. Effective public health efforts to reduce the harms of substance use among young people are critically important. Evidence supporting the effectiveness of substance use prevention for young people is mixed with most evidence supporting universal programs, which target early (12–14 years) to middle (15 years) adolescents. With the recent downward trend in early and mid adolescent substance use, late adolescence now represents the average age of initial substance use exposure and is a critical period to prevent harmful trajectories of substance use. Late adolescence, when young people are in the senior years of their school education, represents an optimal developmental period to intervene; however, age-appropriate interventions targeting late adolescents (16–19 years) are extremely limited. This chapter will assess current approaches to substance use prevention and explore new opportunities to enhance the effectiveness of prevention among both low- and high-risk young people.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Subscribe and save

Springer+ Basic
EUR 32.99 /Month
  • Get 10 units per month
  • Download Article/Chapter or Ebook
  • 1 Unit = 1 Article or 1 Chapter
  • Cancel anytime
Subscribe now

Buy Now

Chapter
EUR 29.95
Price includes VAT (Germany)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
EUR 1,925.99
Price includes VAT (Germany)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Hardcover Book
EUR 534.99
Price includes VAT (Germany)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free ship** worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Similar content being viewed by others

Abbreviations

10–14 years:

Early adolescents

10–19 years:

Adolescents

10–24 years:

Young people

15 years:

Mid adolescents

16–19 years:

Late adolescents

20–24 years:

Young adults

ATS:

Amphetamine-type stimulants

MDMA:

Methylenedioxymethamphetamine

PFC:

Prefrontal cortex

SAMHSA:

Substance Abuse and Mental Health Services Administration

SANE:

Seductive allure of neuroscience explanations

UK:

United Kingdom

UNODC:

United Nations Office on Drugs and Crime

USA:

United States

WHO:

World Health Organization

References

  • Agabio R, Trincas G, Floris F et al (2015) A systematic review of school-based alcohol and other drug prevention Programs. Clin Pract Epidemiol Ment Health 11

    Google Scholar 

  • Antti M, Anni-Emilia A, Caroline S et al (2021) Age of first alcohol intoxication and psychiatric disorders in young adulthood–A prospective birth cohort study. Addict Behav 118:106910

    Article  Google Scholar 

  • Aos S, Lieb R, Mayfield J et al (2004) Benefits and costs of prevention and early intervention programs for youth. Washington State Institute for Public Policy, Olympia

    Google Scholar 

  • Atkinson A, McAuley A, Trayner K et al (2019) ‘We are still obsessed by this idea of abstinence’: a critical analysis of UK news media representations of proposals to introduce drug consumption rooms in Glasgow, UK. Int J Drug Policy 68:62–74

    Article  CAS  PubMed  Google Scholar 

  • Australian Institute of Health and Welfare (2020) National Drug Strategy Household Survey 2020. AIHW, Canberra

    Google Scholar 

  • Babor TF, Babor T, Caetano R, et al (2010) Alcohol: no ordinary commodity: research and public policy

    Google Scholar 

  • Bacon ER, Brinton RD (2021) Epigenetics of the develo** and aging brain: mechanisms that regulate onset and outcomes of brain reorganization. Neurosci Biobehav Rev 125:503

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Blakemore S-J (2019) Adolescence and mental health. Lancet (British edition) 393(10185):2030–2031

    Google Scholar 

  • Bloomfield K (2020) Understanding the alcohol-harm paradox: what next? Lancet Public Health 5(6):e300–e3e1

    Article  PubMed  Google Scholar 

  • Botvin GJ (2000) Preventing drug abuse in schools: social and competence enhancement approaches targeting individual-level etiologic factors. Addict Behav 25(6):887–897

    Article  CAS  PubMed  Google Scholar 

  • Calear AL, Christensen H, Freeman A et al (2016) A systematic review of psychosocial suicide prevention interventions for youth. Eur Child Adolesc Psychiatry 25(5):467–482

    Article  PubMed  Google Scholar 

  • Caluzzi G, Livingston M, Holmes J, et al (2021) Declining drinking among adolescents: are we seeing a denormalisation of drinking and a normalisation of non-drinking? Addiction

    Google Scholar 

  • Carbia C, López-Caneda E, Corral M et al (2018) A systematic review of neuropsychological studies involving young binge drinkers. Neurosci Biobehav Rev 90:332–349

    Article  PubMed  Google Scholar 

  • Caria MP, Faggiano F, Bellocco R et al (2011) The influence of socioeconomic environment on the effectiveness of alcohol prevention among European students: a cluster randomized controlled trial. BMC Public Health 11(1):1–8

    Article  Google Scholar 

  • Cerdá M, Mauro C, Hamilton A et al (2020) Association between recreational marijuana legalization in the United States and changes in marijuana use and cannabis use disorder from 2008 to 2016. JAMA Psychiat 77(2):165–171

    Article  Google Scholar 

  • Champion KE, Newton NC, Teesson M (2016) Prevention of alcohol and other drug use and related harm in the digital age: what does the evidence tell us? Curr Opin Psychiatry vol in press

    Google Scholar 

  • Champion KE, Newton NC, Stapinski L et al (2018) Cluster randomised controlled trial of an online intervention to prevent ecstasy and new psychoactive substance use among adolescents: final results and implications for implementation. BMJ Open 8(11):e020433

    Article  PubMed  PubMed Central  Google Scholar 

  • Champion KE, Parmenter B, McGowan C et al (2019) Effectiveness of school-based eHealth interventions to prevent multiple lifestyle risk behaviours among adolescents: a systematic review and meta-analysis. Lancet Digital Health 1(5):e206–ee21

    Article  PubMed  Google Scholar 

  • Chapman C, Slade T, Hunt C et al (2015) Delay to first treatment contact for alcohol use disorder. Drug Alcohol Depend 147:116–121

    Article  PubMed  Google Scholar 

  • D’Amico EJ, Tucker JS, Miles JN et al (2012) Preventing alcohol use with a voluntary after-school program for middle school students: results from a cluster randomized controlled trial of CHOICE. Prev Sci 13(4):415–425

    Article  PubMed  PubMed Central  Google Scholar 

  • Das JK, Salam RA, Arshad A et al (2016) Interventions for adolescent substance abuse: an overview of systematic reviews. J Adolesc Health 59(4):S61–S75

    Article  PubMed  PubMed Central  Google Scholar 

  • Debenham J, Newton N, Birrell L et al (2019) Alcohol and other drug prevention for older adolescents: it’s a no brainer. Drug Alcohol Rev 38:327–330

    Article  PubMed  Google Scholar 

  • Debenham J, Birrell L, Champion K et al (2020) A pilot study of a neuroscience-based, harm minimisation programme in schools and youth centres in Australia. BMJ Open 10(2)

    Google Scholar 

  • Debenham J, Birrell L, Champion K et al (2021) Neuropsychological and neurophysiological predictors and consequences of cannabis and illicit substance use during neurodevelopment: a systematic review of longitudinal studies. Lancet Child Adolesc Health 5:589

    Article  PubMed  Google Scholar 

  • Degenhardt L, Stockings E, Patton G et al (2016) The increasing global health priority of substance use in young people. Lancet Psychiatry 3:251

    Article  PubMed  Google Scholar 

  • Degenhardt L, Charlson F, Ferrari A et al (2018) The global burden of disease attributable to alcohol and drug use in 195 countries and territories, 1990–2016: a systematic analysis for the global burden of disease study 2016. Lancet Psychiatry 5(12):987–1012

    Article  Google Scholar 

  • Faggiano F, Minozzi S, Versino E, et al (2014) Universal school-based prevention for illicit drug use (review) https://doi.org/10.1002/14651858.CD003020.pub3

  • Foxcroft DR, Tsertsvadze A (2012) Cochrane review: universal school-based prevention programs for alcohol misuse in young people. Evidence-Based Child Health 7(2):450–575

    Article  Google Scholar 

  • Francis-Oliviero F, Cambon L, Wittwer J et al (2020) Theoretical and practical challenges of proportionate universalism: a review. Revista Panamericana de Salud Pública 44

    Google Scholar 

  • Gislason T, Yngvadottir A, Benediktsdottir B (1995) Alcohol consumption, smoking and drug abuse among Icelandic teenagers: a study into the effectiveness of the ‘Skills for adolescence’ programme. Drugs 2(3):243–258

    Google Scholar 

  • Gordon RS (1983) An operational classification of disease prevention. Public Health Rep 98(2):107

    PubMed  PubMed Central  Google Scholar 

  • Guerin N, White V (2018) ASSAD 2017 Statistics & trends: Australian secondary students’ use of tobacco, alcohol, over-the-counter drugs, and illicit substances. Cancer Council Victoria

    Google Scholar 

  • Guerri C, Pascual M (2010) Mechanisms involved in the neurotoxic, cognitive, and neurobehavioral effects of alcohol consumption during adolescence. Alcohol 44(1):15–26

    Article  CAS  PubMed  Google Scholar 

  • Haggerty RJ, Mrazek PJ (1994) Reducing risks for mental disorders: Frontiers for preventive intervention research

    Google Scholar 

  • Hall WDP, Patton GP, Stockings EP et al (2016) Why young people’s substance use matters for global health. Lancet Psychiatry 3(3):265–279

    Article  PubMed  Google Scholar 

  • Hamidullah S, Thorpe HHA, Frie JA et al (2020) Adolescent substance use and the brain: behavioral, cognitive and neuroimaging correlates. Front Hum Neurosci 14

    Google Scholar 

  • Han B, Compton WM, Blanco C et al (2017) National trends in substance use and use disorders among youth. J Am Acad Child Adolesc Psychiatry 56(9):747–54.e3

    Article  PubMed  Google Scholar 

  • Harvey SA, McKay MT, Sumnall HR (2016) Adolescents’ reflections on school-based alcohol education in the United Kingdom: education as usual compared with a structured harm reduction intervention. J Subst Abus 21(6):640–645

    Google Scholar 

  • Hecht ML, Marsiglia FF, Elek E et al (2003) Culturally grounded substance use prevention: an evaluation of the keepin’ it REAL curriculum. Prev Sci 4(4):233–248

    Article  PubMed  Google Scholar 

  • Heinz A, Zhao X, Liu S (2020) Implications of the association of social exclusion with mental health. JAMA Psychiat 77(2):113–114

    Article  Google Scholar 

  • Hennessy EA, Tanner-Smith EE (2015) Effectiveness of brief school-based interventions for adolescents: a meta-analysis of alcohol use prevention programs. Prev Sci 16(3):463–474

    Article  PubMed  PubMed Central  Google Scholar 

  • Hides L, Chan G, Dawe S et al (2021) Direction of the relationship between methamphetamine use and positive psychotic symptoms in regular methamphetamine users: evidence from a prospective cohort study. Br J Psychiatry 219(1):361–367

    Article  PubMed  Google Scholar 

  • Hunt GE, Malhi GS, Lai HMX et al (2020) Prevalence of comorbid substance use in major depressive disorder in community and clinical settings, 1990–2019: systematic review and meta-analysis. J Affect Disord 266:288–304

    Article  PubMed  Google Scholar 

  • Im SH, Varma K, Varma S (2017) Extending the seductive allure of neuroscience explanations effect to popular articles about educational topics. Br J Educ Psychol 87(4):518–534

    Article  PubMed  Google Scholar 

  • Istaphanous GK, Ward CG, Loepke AW (2010) The impact of the perioperative period on neurocognitive development, with a focus on pharmacological concerns. Best Pract Res Clin Anaesthesiol 24(3):433–449

    Article  PubMed  Google Scholar 

  • Jackson KM (2008) Heavy episodic drinking: determining the predictive utility of five or more drinks. Psychol Addict Behav 22(1):68–77

    Article  PubMed  PubMed Central  Google Scholar 

  • Johnston LD, Miech RA, O’Malley PM et al (2020) Monitoring the future national survey results on drug use, 1975–2019: overview, key findings on adolescent drug use. Institute for Social Research, The University of Michigan, Michigan, ED594190, Ann Arbor

    Book  Google Scholar 

  • Jones L, McCoy E, Bates G et al (2015) Understanding the alcohol harm paradox. Alcohol Research UK, London

    Google Scholar 

  • Kraus L, Seitz NN, Piontek D et al (2018) ‘Are The Times A-Changin’? Trends in adolescent substance use in Europe. Addiction (Abingdon) 113(7):1317–1332

    Article  Google Scholar 

  • Lees B, Mewton L, Stapinski LA et al (2019) Neurobiological and cognitive profile of young binge drinkers: a systematic review and meta-analysis. Neuropsychol Rev:1–29

    Google Scholar 

  • Lees B, Meredith LR, Kirkland AE et al (2020) Effect of alcohol use on the adolescent brain and behavior. Pharmacol Biochem Behav 192:172906

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Lenroot RK, Giedd JN (2006) Brain development in children and adolescents: insights from anatomical magnetic resonance imaging. Neurosci Biobehav Rev 30(6):718–729

    Article  PubMed  Google Scholar 

  • Longshore D, Ghosh-Dastidar B, Ellickson PL (2006) National Youth Anti-Drug Media Campaign and school-based drug prevention: evidence for a synergistic effect in ALERT plus. Addict Behav 31(3):496–508

    Article  PubMed  Google Scholar 

  • Luikinga SJ, Kim JH, Perry CJ (2018) Developmental perspectives on methamphetamine abuse: exploring adolescent vulnerabilities on brain and behavior. Prog Neuro-Psychopharmacol Biol Psychiatry 87:78–84

    Article  CAS  Google Scholar 

  • Marconi A, Di Forti M, Lewis CM et al (2016) Meta-analysis of the association between the level of cannabis use and risk of psychosis. Schizophr Bull 42(5):1262–1269

    Article  PubMed  PubMed Central  Google Scholar 

  • Marel C, Mills KL, Teesson M (2021) Substance use, mental disorders and COVID-19: a volatile mix. Curr Opin Psychiatry 34(4):351

    Article  PubMed  PubMed Central  Google Scholar 

  • Marmot M (2013) Fair society, healthy lives. Fair Soc Healthy Lives:1–74

    Google Scholar 

  • McBride N, Farringdon F, Midford R et al (2004) Harm minimization in school drug education: final results of the school health and alcohol harm reduction project (SHAHRP). Addiction 99(3):278–291

    Article  PubMed  Google Scholar 

  • McBride N, Farringdon F, Muleners L et al (2006) School health and alcohol harm reduction project: details of intervention development and research procedures. National Drug Research Institute, Curtin University of Technology, Perth

    Google Scholar 

  • McCabe DP, Castel AD (2008) Seeing is believing: the effect of brain images on judgments of scientific reasoning. Cognition 107(1):343–352

    Article  PubMed  Google Scholar 

  • McKay M, Sumnall H, McBride N et al (2014) The differential impact of a classroom-based, alcohol harm reduction intervention, on adolescents with different alcohol use experiences: a multi-level growth modelling analysis. J Adolesc 37(7):1057–1067

    Article  PubMed  Google Scholar 

  • McLaren L (2019) In defense of a population-level approach to prevention: why public health matters today. Can J Public Health 110(3):279–284

    Article  PubMed  PubMed Central  Google Scholar 

  • Melchior M, Nakamura A, Bolze C et al (2019) Does liberalisation of cannabis policy influence levels of use in adolescents and young adults? A systematic review and meta-analysis. BMJ Open 9(7):e025880

    Article  PubMed  PubMed Central  Google Scholar 

  • Mewton L, Lees B, Squeglia L, et al (2020) The relationship between brain structure and general psychopathology in preadolescents

    Google Scholar 

  • Midford R, Cahill H, Ramsden R et al (2012) Alcohol prevention: what can be expected of a harm reduction focused school drug education programme? Drugs 19(2):102–110

    Google Scholar 

  • Midford R, Mitchell J, Lester L et al (2014) Preventing alcohol harm: early results from a cluster randomised, controlled trial in Victoria, Australia of comprehensive harm minimisation school drug education. Int J Drug Policy 25(1):142–150

    Article  PubMed  Google Scholar 

  • Miller TR, Hendrie D (2009) Substance abuse prevention dollars and cents: a cost-benefit analysis. US Department of Health and Human Services, Substance Abuse and Mental …

    Google Scholar 

  • Mills KL, Goddings A-L, Herting MM et al (2016) Structural brain development between childhood and adulthood: convergence across four longitudinal samples. NeuroImage 141:273–281

    Article  PubMed  Google Scholar 

  • Murray CJ, Aravkin AY, Zheng P et al (2020) Global burden of 87 risk factors in 204 countries and territories, 1990–2019: a systematic analysis for the global burden of disease study 2019. Lancet 396(10258):1223–1249

    Article  Google Scholar 

  • Newton NC, Andrews G, Champion KE et al (2014a) Universal internet-based prevention for alcohol and cannabis use reduces truancy, psychological distress and moral disengagement: a cluster randomised controlled trial. Prev Med 65:109–115

    Article  PubMed  Google Scholar 

  • Newton NC, Deady M, Teesson M (2014b) Alcohol and substance use prevention and early intervention. Early Interv Psychiatry:201–217

    Google Scholar 

  • Newton NC, Stapinski L, Slade T et al (2021) The 7-year effectiveness of school-based alcohol use prevention from adolescence to early adulthood: an RCT of universal, selective and combined interventions. J Am Acad Child Adolesc Psychiatry, vol Accepted 26th August, 2021

    Google Scholar 

  • Odgers CL, Jensen MR (2020) Adolescent development and growing divides in the digital age. Dialogues Clin Neurosci 22(2):143

    Article  PubMed  PubMed Central  Google Scholar 

  • Oldham M, Callinan S, Whitaker V et al (2020) The decline in youth drinking in England – is everyone drinking less? A quantile regression analysis. Addiction 115(2):230–238

    Article  PubMed  Google Scholar 

  • Onrust SA, Otten R, Lammers J et al (2016) School-based programmes to reduce and prevent substance use in different age groups: what works for whom? Systematic review and meta-regression analysis. Clin Psychol Rev 44:45–59

    Article  PubMed  Google Scholar 

  • Orsini MM, Wyrick DL, Hansen WB et al (2019) Evaluation of an infused alcohol and drug prevention programme. Health Educ 119:230

    Article  Google Scholar 

  • Padget A, Bell ML, Shamblen SR et al (2005) Effects on high school students of teaching a cross-age alcohol prevention program. J Drug Educ 35(3):201–216

    Article  PubMed  Google Scholar 

  • Patton GC, Sawyer SM, Santelli JS et al (2016) Our future: a lancet commission on adolescent health and wellbeing. Lancet 387(10036):2423–2478

    Article  PubMed  PubMed Central  Google Scholar 

  • Perry CL, Komro KA, Veblen-Mortenson S et al (2003) A randomized controlled trial of the middle and junior high school DARE and DARE plus programs. Arch Pediatr Adolesc Med 157(2):178–184

    Article  PubMed  Google Scholar 

  • Pettigrew J, Graham JW, Miller-Day M et al (2015) Adherence and delivery: implementation quality and program outcomes for the seventh-grade keepin’ it REAL program. Prev Sci 16(1):90–99

    Article  PubMed  PubMed Central  Google Scholar 

  • Plunk AD, Cavazaos-Rehg P, Bierut LJ et al (2013) The persistent effects of minimum legal drinking age laws on drinking patterns later in life. Alcohol Clin Exp Res 37(3):463–469

    Article  PubMed  PubMed Central  Google Scholar 

  • Rakesh D, Lv J, Zalesky A et al (2021) Altered resting functional connectivity patterns associated with problematic substance use and substance use disorders during adolescence. J Affect Disord 279:599–608

    Article  PubMed  Google Scholar 

  • Rehm J, Kilian C, Ferreira-Borges C et al (2020) Alcohol use in times of the COVID 19: implications for monitoring and policy. Drug Alcohol Rev 39(4):301–304

    Article  PubMed  PubMed Central  Google Scholar 

  • Rusby JC, Westling E, Crowley R et al (2018) Legalization of recreational marijuana and community sales policy in Oregon: impact on adolescent willingness and intent to use, parent use, and adolescent use. Psychol Addict Behav 32(1):84

    Article  PubMed  Google Scholar 

  • SAMHSA (2019) National Survey on drug use and health 2018–2019 estimated totals by state. U.S. Department of Health and Human Services

    Google Scholar 

  • Schulenberg J, Maggs JL (2001) Moving targets: modeling developmental trajectories of adolescent alcohol misuse, individual and peer risk factors, and intervention effects. Appl Dev Sci 5(4):237–253

    Article  Google Scholar 

  • Scott J, Slomiak ST, Jones JD et al (2018) Association of cannabis with cognitive functioning in adolescents and young adults: a systematic review and meta-analysis. JAMA Psychiat

    Google Scholar 

  • Shollenbarger SG, Price J, Wieser J et al (2015) Impact of cannabis use on prefrontal and parietal cortex gyrification and surface area in adolescents and emerging adults. Dev Cogn Neurosci 16:46–53

    Article  PubMed  PubMed Central  Google Scholar 

  • Slade T, Newton NC, Mather M, et al (2020) The long-term effectiveness of universal, selective and combined prevention for alcohol use during adolescence: 36-month outcomes from a cluster randomized controlled trial. Addiction

    Google Scholar 

  • Solmi M, Radua J, Olivola M et al (2021) Age at onset of mental disorders worldwide: large-scale meta-analysis of 192 epidemiological studies. Mol Psychiatry:1–15

    Google Scholar 

  • Somerville LH (2016) Searching for signatures of brain maturity: what are we searching for? Neuron 92(6):1164–1167

    Article  CAS  PubMed  Google Scholar 

  • Southwell M, Shelly S, MacDonald V et al (2019) Transforming lives and empowering communities: evidence, harm reduction and a holistic approach to people who use drugs. Curr Opin HIV AIDS 14(5):409–414

    Article  PubMed  Google Scholar 

  • Spear LP (2018) Effects of adolescent alcohol consumption on the brain and behaviour. Nat Rev Neurosci 19(4):197–214

    Article  CAS  PubMed  Google Scholar 

  • Spoth R, Trudeau L, Redmond C et al (2016) Replicating and extending a model of effects of universal preventive intervention during early adolescence on young adult substance misuse. J Consult Clin Psychology 84(10):913

    Article  Google Scholar 

  • Spurling MC, Vinson DC (2005) Alcohol-related injuries: evidence for the prevention paradox. Ann Fam Med 3(1):47–52

    Article  PubMed  PubMed Central  Google Scholar 

  • Squeglia LM, Gray KM (2016) Alcohol and drug use and the develo** brain. Curr Psychiatry Rep 18(5):46

    Article  PubMed  PubMed Central  Google Scholar 

  • Stapinski L, Lawler S, Reda B et al (2017) Empowering young people to make positive choices: evidence-based resources for the prevention of alcohol and other drug use in Australian schools. Mystery Train 2007

    Google Scholar 

  • Stockings E, Hall WD, Lynskey M et al (2016) Prevention, early intervention, harm reduction, and treatment of substance use in young people. Lancet Psychiatry 3:280

    Article  PubMed  Google Scholar 

  • Stone AL, Becker LG, Huber AM et al (2012) Review of risk and protective factors of substance use and problem use in emerging adulthood. Addict Behav 37(7):747–775

    Article  PubMed  Google Scholar 

  • Strøm HK, Adolfsen F, Fossum S et al (2014) Effectiveness of school-based preventive interventions on adolescent alcohol use: a meta-analysis of randomized controlled trials. Subst Abuse Treat Prev Policy 9(1):1–11

    Article  Google Scholar 

  • Sun P, Sussman S, Dent CW et al (2008) One-year follow-up evaluation of project towards no drug abuse (TND-4). Prev Med 47(4):438–442

    Article  PubMed  PubMed Central  Google Scholar 

  • Swisher JD, Nesselroade C, Tatanish C (1985) Here’s looking at you two is looking good: an experimental analysis. J Humanist Couns Educ Dev 23:111

    Article  Google Scholar 

  • Tamnes CK, Herting MM, Goddings AL et al (2017) Development of the cerebral cortex across adolescence: a multisample study of inter-related longitudinal changes in cortical volume, surface area, and thickness. J Neurosci 37(12):3402–3412

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Taylor BJ, Graham JW, Cumsille P et al (2000) Modeling prevention program effects on growth in substance use: analysis of five years of data from the adolescent alcohol prevention trial. Prev Sci 1(4):183–197

    Article  CAS  PubMed  Google Scholar 

  • Teesson M, Degenhardt L, Lynskey M et al (2005) The relationships between substance use and mental health problems: evidence from longitudinal studies. In: Preventing harmful substance use: the evidence base for policy and practice. Wiley, pp 43–51

    Chapter  Google Scholar 

  • Teesson M, Hall W, Slade T et al (2010) Prevalence and correlates of DSM-IV alcohol abuse and dependence in Australia: findings of the 2007 National Survey of mental health and wellbeing. Addiction 105(12):2085–2094

    Article  PubMed  Google Scholar 

  • Teesson M, Newton NC, Barrett EL (2012) Australian school-based prevention programs for alcohol and other drugs: a systematic review. Drug Alcohol Rev 31(6):731–736

    Article  PubMed  Google Scholar 

  • Teesson M, Newton NC, Slade T et al (2020) Combined prevention for substance use, depression, and anxiety in adolescence: a cluster-randomised controlled trial of a digital online intervention. Lancet Digital Health 2(2):e74–e84

    Article  PubMed  Google Scholar 

  • Tremblay M, Baydala L, Khan M et al (2020) Primary substance use prevention programs for children and youth: a systematic review. Pediatrics 146(3)

    Google Scholar 

  • Twenge JM, Park H (2019) The decline in adult activities among U.S. Adolescents, 1976–2016. Child Dev 90(2):638–654

    Article  PubMed  Google Scholar 

  • UNODC (2018) International standards on drug use prevention, second updated edition. United Nations Office on Drugs and Crime and the World Health Organization, Vienna

    Google Scholar 

  • Välimäki M, Anttila K, Anttila M et al (2017) Web-based interventions supporting adolescents and young people with depressive symptoms: systematic review and meta-analysis. JMIR mHealth uHealth 5(12):e180-e

    Article  Google Scholar 

  • Viner RM, Ozer EM, Denny S et al (2012) Adolescence and the social determinants of health. Lancet 379(9826):1641–1652

    Article  PubMed  Google Scholar 

  • Weisberg DS, Keil FC, Goodstein J et al (2008) The seductive allure of neuroscience explanations. J Cogn Neurosci 20(3):470–477

    Article  PubMed  PubMed Central  Google Scholar 

  • Wilson J, Freeman TP, Mackie CJ (2019) Effects of increasing cannabis potency on adolescent health. Lancet Child Adolesc Health 3(2):121–128

    Article  PubMed  Google Scholar 

  • Workman JW, Moore D, Huber MJ et al (2012) The PALS prevention program and its long-term impact on student intentions to use alcohol, tobacco, and marijuana. J Drug Educ 42(4):469–485

    Article  PubMed  Google Scholar 

  • World Drug Report (2020) Drug use and health consequences. United Nations

    Google Scholar 

  • World Health Organization (2018) Global Status Report on Alcohol and Health 2018. World Health Organization, Geneva; 2018. License: CC BY-NC-SA 3.0 IGO

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Jennifer Debenham .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2022 Springer Nature Switzerland AG

About this entry

Check for updates. Verify currency and authenticity via CrossMark

Cite this entry

Debenham, J., Newton, N.C., Champion, K.E., Teesson, M. (2022). Substance Use in Older Adolescence: Overcoming the Prevention Paradox. In: Patel, V.B., Preedy, V.R. (eds) Handbook of Substance Misuse and Addictions. Springer, Cham. https://doi.org/10.1007/978-3-030-92392-1_20

Download citation

Publish with us

Policies and ethics

Navigation