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Therapeutic Potential of Cyanobacteria as a Producer of Novel Bioactive Compounds

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Cyanobacterial Biotechnology in the 21st Century

Abstract

Cyanobacteria are photosynthetic prokaryotes that have a variety of biological activities and can be used as dietary supplements. Because of its high nutritional, protein, and digestibility content, it is utilized as a meal supplement. Spirulina sp., Anabaena sp., Microcystis sp., Nostoc sp., Lyngbya sp., Oscillatoria sp., and other cyanobacteria create a wide range of secondary bioactive metabolites with diverse biological functions. Cyanobacteria produce various physiologically active and chemically diverse compounds such as saccharides, fatty acid amides, lipopeptides, cyclic and acyclic peptides, and alkaloids. More than half of marine cyanobacteria could be used to extract bioactive compounds that can destroy cancer cells by causing apoptosis. Their effectiveness as an antiviral, antitumor, antibacterial, anti-HIV, and dietary additive is extensively documented. However, such drugs are in various phases of clinical studies, and only a few have made it to the market. This chapter examines the bioactive chemicals in cyanobacteria with antiprotozoal, antibacterial, anti-inflammatory, anticancer, antioxidant, and antiviral properties.

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Acknowledgments

The authors are thankful to the Head of Centre of Advanced Study in Botany, Institute of Science, Banaras Hindu University, Varanasi, and DST-FIST for providing the necessary research facilities. The University Grants Commission, Government of India, New Delhi, is also acknowledged for providing Senior Research Fellowship (SRF) for financial assistance and ISLS, ISC, and BHU for instrumental facilities.

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Authors and Affiliations

  1. Laboratory of Algal Research, Centre of Advanced Study in Botany, Institute of Science, Banaras Hindu University, Varanasi, India

    Priya Yadav, Rahul Prasad Singh & Rajan Kumar Gupta

  2. Department of Postharvest Science, Agriculture Research Organization, Volcani Center, Rishon LeZion, Israel

    Ajay Kumar

  3. Department of Biotechnology, Mizoram University (A Central University), Pachhunga University College Campus, Aizawl, India

    Prashant Kumar Singh

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Correspondence to Rajan Kumar Gupta .

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Editors and Affiliations

  1. School of Environmental & Life Sciences, University of Newcastle, Callaghan, NSW, Australia

    Brett Neilan

  2. Laboratory of Environmental Biotechnology, Federal University of Latin-American Integration (UNILA), Foz do Iguaçu, Paraná, Brazil

    Michel Rodrigo Zambrano Passarini

  3. Department of Biotechnology, Mizoram University, Aizawl, India

    Prashant Kumar Singh

  4. Agriculture Research Organization, Volcani Centre, Israel

    Ajay Kumar

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Yadav, P., Singh, R.P., Kumar, A., Singh, P.K., Gupta, R.K. (2023). Therapeutic Potential of Cyanobacteria as a Producer of Novel Bioactive Compounds. In: Neilan, B., Passarini, M.R.Z., Singh, P.K., Kumar, A. (eds) Cyanobacterial Biotechnology in the 21st Century. Springer, Singapore. https://doi.org/10.1007/978-981-99-0181-4_13

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