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Investigation of Infectious Agents Causing Spontaneous Hepatitis in LEC Rats

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The LEC Rat

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Abstract

Two strains of Long-Evans rats, LEC and LEA were separated according to their coat colors. Acute hepatitis tends to occur spontaneously in the LEC rats after the 24th generation. As has been previously reported [1–3], the clinical course of the disease and the histopathological features closely resemble human fulminant hepatitis.

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References

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Author information

Authors and Affiliations

  1. Laboratory of Pathology, Cancer Institute, Japan

    Tsutomu Namieno, Noritoshi Takeichi & Hiroshi Kobayashi

  2. First Department of Surgery, School of Medicine, Hokkaido University, Sapporo, 060, Japan

    Tsutomu Namieno & Jun-ichi Uchino

  3. Sasaki Cancer Institute, Chiyoda-ku, Tokyo, 101, Japan

    Motomichi Sasaki

  4. Department of Pathology, Sapporo Medical College, Sapporo, 060, Japan

    Kimimaro Dempo & Michio Mori

Authors
  1. Tsutomu Namieno
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  2. Noritoshi Takeichi
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  3. Motomichi Sasaki
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  4. Kimimaro Dempo
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  5. Michio Mori
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  6. Jun-ichi Uchino
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  7. Hiroshi Kobayashi
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Editor information

Editors and Affiliations

  1. Department of Pathology, Sapporo Medical College, Minami 1, Nishi 17, Chuo-ku, Sapporo, 060, Japan

    Michio Mori M.D., Ph.D.

  2. Chromosome Research Unit, Faculty of Science, Hokkaido University, Kita 10, Nishi 8, Kita-ku Sapporo, 060, Japan

    Michihiro C. Yoshida D.Si., Ph.D.

  3. Laboratory of Pathology, Cancer Institute, Hokkaido University School of Medicine, Kita 15, Nishi 7, Kita-ku, Sapporo, 060, Japan

    Noritoshi Takeichi M.D., Ph.D.

  4. Department of Biochemistry, Osaka University Medical School, 2–2 Yamadaoka, Suita, Osaka, 565, Japan

    Naoyuki Taniguchi M.D., Ph.D.

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© 1991 Springer-Verlag Tokyo

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Namieno, T. et al. (1991). Investigation of Infectious Agents Causing Spontaneous Hepatitis in LEC Rats. In: Mori, M., Yoshida, M.C., Takeichi, N., Taniguchi, N. (eds) The LEC Rat. Springer, Tokyo. https://doi.org/10.1007/978-4-431-68153-3_7

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  • DOI: https://doi.org/10.1007/978-4-431-68153-3_7

  • Publisher Name: Springer, Tokyo

  • Print ISBN: 978-4-431-68155-7

  • Online ISBN: 978-4-431-68153-3

  • eBook Packages: Springer Book Archive

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