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Drug Releasing Mechanism from Redox Active Micelles

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Advanced Biomaterials in Biomedical Engineering and Drug Delivery Systems

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Summary

Electrochemical reaction of FPEG is coupled with the preceding disassembled reaction of micelles in aqueous solution. The change in diffusion species fromthe micelles to the monomers at cmc in the concentration gradient in diffusion layers appeared in case of bulk electrolysis of FPEG. The drug releasing mechanism from the redox active micelles were clarified.

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References

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Author information

Authors and Affiliations

  1. Department of Chemistry, Faculty of Science and Technology, Sophia University, 7-1, Kioi-cho, Chiyoda-ku, Tokyo 102, Japan

    Yukikazu Takeoka, Takashi Aoki, Kohei Sanui & Naoya Ogata

  2. Institute of Biomedical Engineering, Tokyo Women’s Medical College, 1-8 Kawada-cho, Shinjuku-ku, Tokyo 162, Japan

    Teruo Okano & Yasuhisa Sakurai

  3. Department of Chemistry, Yokohama National University, 156 Tokiwadai, Hodogaya-ku, Yokohama 240, Japan

    Masayoshi Watanabe

Authors
  1. Yukikazu Takeoka
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  2. Takashi Aoki
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  3. Kohei Sanui
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  4. Naoya Ogata
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  5. Teruo Okano
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  6. Yasuhisa Sakurai
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  7. Masayoshi Watanabe
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Editor information

Editors and Affiliations

  1. Department of Chemistry, Sophia University, 7-1 Kioi-cho, Chiyoda-ku, Tokyo, 102, Japan

    Naoya Ogata Ph.D. (Professor) (Professor)

  2. Center for Controlled Chemical Delivery, Department of Pharmaceutics and Pharmaceutical Chemistry, University of Utah, Salt Lake City, UT, 84112, USA

    Sung Wan Kim Ph.D. (Professor and Director) (Professor and Director)

  3. Department of Chemical Technology and Institute of Biomedical Technology, University of Twente, P.O. Box 217, 7500 AD, Enschede, The Netherlands

    Jan Feijen Ph.D. (Professor) (Professor)

  4. Institute of Biomedical Engineering, Tokyo Women’s Medical College, 8-1 Kawada-cho, Shinjuku-ku, Tokyo, 162, Japan

    Teruo Okano Ph.D. (Professor) (Professor)

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© 1996 Springer-Verlag Tokyo

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Takeoka, Y. et al. (1996). Drug Releasing Mechanism from Redox Active Micelles. In: Ogata, N., Kim, S.W., Feijen, J., Okano, T. (eds) Advanced Biomaterials in Biomedical Engineering and Drug Delivery Systems. Springer, Tokyo. https://doi.org/10.1007/978-4-431-65883-2_121

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  • DOI: https://doi.org/10.1007/978-4-431-65883-2_121

  • Publisher Name: Springer, Tokyo

  • Print ISBN: 978-4-431-65885-6

  • Online ISBN: 978-4-431-65883-2

  • eBook Packages: Springer Book Archive

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