Abstract
The effect of chemotherapy on the outcome of allograft reconstruction procedures after the resection of bone tumors is of considerable interest in the light of both experimental [1,2] and clinical evidence [3,4] suggesting that it has an adverse effect on bone repair. The crucial clinical issue, however, is whether the failure of allograft reconstruction due to infection, fracture, or both [5], is especially frequent when performed concomitant with administration of chemotherapy. We addressed this question by evaluating the clinical results and complications of segmental allograft replacement in a group of young patients who were followed prospectively and of whom the majority had high grade sarcomas and were treated with neoadjuvant chemotherapy protocols.
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© 1991 Springer-Verlag Berlin Heidelberg
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Czitrom, A., Capanna, R., Donati, D., Bacci, G., Campanacci, M. (1991). Segmental Allograft Reconstruction Concomitant with Neoadjuvant Chemotherapy. In: Langlais, F., Tomeno, B. (eds) Limb Salvage. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-75879-9_12
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DOI: https://doi.org/10.1007/978-3-642-75879-9_12
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