Part of the book series: Handbook of Experimental Pharmacology ((HEP,volume 87 / 1))

  • 286 Accesses

Abstract

Classically, the involvement of lymphocytes in inflammatory skin lesions has been associated with immunological responses, whereby the host expresses, or develops, enhanced reactivity to an inciting allergen. Yet it is also known that lymphocytes can contribute to inflammatory responses induced by non-allergic stimuli. These observations may be reconciled by considering the allergic response to be an enhanced version of a non-selective inflammatory response involving lymphocyte activation.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Subscribe and save

Springer+ Basic
EUR 32.99 /Month
  • Get 10 units per month
  • Download Article/Chapter or Ebook
  • 1 Unit = 1 Article or 1 Chapter
  • Cancel anytime
Subscribe now

Buy Now

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 84.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free ship** worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

Similar content being viewed by others

References

  • Bloom BR, Bennett B (1966) Mechanisms of a reaction in vitro associated with delayed type hypersensitivity. Science 153:80–82

    Article  PubMed  CAS  Google Scholar 

  • David JR (1966) Delayed hypersensitivity in vitro:its mediation by cell-free substances formed by lymphoid cell antigen interaction. Proc Natl Acad Sci USA 56:72–77

    Article  PubMed  CAS  Google Scholar 

  • David JR, Lawrence HS, Thomas L (1964) Delayed hypersensitivity in vitro. II. Effect of sensitive cells on normal cells in the presence of antigen. J Immunol 93:274–278

    PubMed  CAS  Google Scholar 

  • George M, Vaughan JH (1962) In vitro cell migration as a model for delayed hypersensitivity. Proc Soc Exp Biol Med 111:514–521

    PubMed  CAS  Google Scholar 

  • Hanson JM, Rumjanek VM, Morley J (1982) Mediators of cellular immune reactions. Pharmacology and therapeutics 17:165–198

    Article  PubMed  CAS  Google Scholar 

  • Morley J (1974) Prostaglandins and lymphokines in arthritis. Prostaglandins 8:315–326

    Article  PubMed  CAS  Google Scholar 

  • Oppenheim JJ, Mizel SB, Meltzer MS (1979) Biological effects of lymphocyte and macrophage-derived mitogenic “amplication” factors. In:Cohen S, Pick E, Oppenheim JJ (eds) Biology of the lymphokines. Academic, New York, pp 291–323

    Google Scholar 

  • Szamel M, Resch K (1981) Modulation of enzyme activities in isolated lymphocyte plasma membranes by enzymatic modification of phospholipid fatty acids. J Biol Chem 256:11618–11623

    PubMed  CAS  Google Scholar 

Download references

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 1989 Springer-Verlag Berlin Heidelberg

About this chapter

Cite this chapter

Morley, J. (1989). Lymphocytes. In: Greaves, M.W., Shuster, S. (eds) Pharmacology of the Skin I. Handbook of Experimental Pharmacology, vol 87 / 1. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-73797-8_9

Download citation

  • DOI: https://doi.org/10.1007/978-3-642-73797-8_9

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-73799-2

  • Online ISBN: 978-3-642-73797-8

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics

Navigation