Symmetry-Enhanced Attention Network for Acute Ischemic Infarct Segmentation with Non-contrast CT Images

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Medical Image Computing and Computer Assisted Intervention – MICCAI 2021 (MICCAI 2021)

Part of the book series: Lecture Notes in Computer Science ((LNIP,volume 12907))

Abstract

Quantitative estimation of the acute ischemic infarct is crucial to improve neurological outcomes of the patients with stroke symptoms. Since the density of lesions is subtle and can be confounded by normal physiologic changes, anatomical asymmetry provides useful information to differentiate the ischemic and healthy brain tissue. In this paper, we propose a symmetry enhanced attention network (SEAN) for acute ischemic infarct segmentation. Our proposed network automatically transforms an input CT image into the standard space where the brain tissue is bilaterally symmetric. The transformed image is further processed by a U-shape network integrated with the proposed symmetry enhanced attention for pixel-wise labelling. The symmetry enhanced attention can efficiently capture context information from the opposite side of the image by estimating long-range dependencies. Experimental results show that the proposed SEAN outperforms some symmetry-based state-of-the-art methods in terms of both dice coefficient and infarct localization.

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References

  1. Avants, B.B., Tustison, N., Song, G.: Advanced normalization tools (ants). Insight J 2(365), 1–35 (2009)

    Google Scholar 

  2. Barber, P.A., Demchuk, A.M., Zhang, J., Buchan, A.M., Group, A.S., et al.: Validity and reliability of a quantitative computed tomography score in predicting outcome of hyperacute stroke before thrombolytic therapy. Lancet 355(9216), 1670–1674 (2000)

    Google Scholar 

  3. Barman, A., Inam, M.E., Lee, S., Savitz, S.I., Sheth, S.A., Giancardo, L.: Determining ischemic stroke from CT-angiography imaging using symmetry-sensitive convolutional networks. In: International Symposium on Biomedical Imaging, pp. 1873–1877 (2019)

    Google Scholar 

  4. Evans, A.C., Collins, D.L., Mills, S., Brown, E.D., Kelly, R.L., Peters, T.M.: 3D statistical neuroanatomical models from 305 MRI volumes. In: 1993 IEEE Conference Record Nuclear Science Symposium and Medical Imaging Conference, pp. 1813–1817. IEEE (1993)

    Google Scholar 

  5. Fang, C., Li, G., Pan, C., Li, Y., Yu, Y.: Globally guided progressive fusion network for 3d pancreas segmentation. In: Shen, D., et al. (eds.) MICCAI 2019. LNCS, vol. 11765, pp. 210–218. Springer, Cham (2019). https://doi.org/10.1007/978-3-030-32245-8_24

    Chapter  Google Scholar 

  6. He, K., Zhang, X., Ren, S., Sun, J.: Deep residual learning for image recognition. In: Computer Vision and Pattern Recognition (2015)

    Google Scholar 

  7. Jaderberg, M., Simonyan, K., Zisserman, A., et al.: Spatial transformer networks. In: Advances in Neural Information Processing Systems, pp. 2017–2025 (2015)

    Google Scholar 

  8. Katan, M., Luft, A.: Global burden of stroke. In: Seminars in Neurology, vol. 38, pp. 208–211. Georg Thieme Verlag (2018)

    Google Scholar 

  9. Khan Academy: Diagnosing strokes with imaging CT, MRI, and angiography. https://www.khanacademy.org

  10. Kuang, H., Menon, B.K., Qiu, W.: Automated infarct segmentation from follow-up non-contrast CT scans in patients with acute ischemic stroke using dense multi-path contextual generative adversarial network. In: Shen, D., et al. (eds.) MICCAI 2019. LNCS, vol. 11766, pp. 856–863. Springer, Cham (2019). https://doi.org/10.1007/978-3-030-32248-9_95

    Chapter  Google Scholar 

  11. Liu, C.F., et al.: Using deep Siamese neural networks for detection of brain asymmetries associated with Alzheimer’s disease and mild cognitive impairment. Magn. Reson. Imaging 64, 190–199 (2019)

    Article  Google Scholar 

  12. Qiu, W., et al.: Machine learning for detecting early infarction in acute stroke with non-contrast-enhanced CT. Radiology 294(3), 638–644 (2020)

    Article  Google Scholar 

  13. Ronneberger, O., Fischer, P., Brox, T.: U-net: convolutional networks for biomedical image segmentation. In: Navab, N., Hornegger, J., Wells, W.M., Frangi, A.F. (eds.) MICCAI 2015. LNCS, vol. 9351, pp. 234–241. Springer, Cham (2015). https://doi.org/10.1007/978-3-319-24574-4_28

    Chapter  Google Scholar 

  14. Wang, X., Girshick, R., Gupta, A., He, K.: Non-local neural networks. In: Proceedings of the IEEE Conference on Computer Vision and Pattern Recognition, pp. 7794–7803 (2018)

    Google Scholar 

  15. Wang, Y., Katsaggelos, A.K., Xue, W., Parrish, T.B.: A deep symmetry convnet for stroke lesion segmentation. In: IEEE International Conference on Image Processing (ICIP) (2016)

    Google Scholar 

  16. Zhang, H., Zhu, X., Willke, T.L.: Segmenting brain tumors with symmetry. In: Proceedings of NIPS Workshop (2017)

    Google Scholar 

Download references

Acknowledgments

This work was supported in part by following grants, MOST-2018AAA0102004, NSFC-62061136001, the Key Program of Bei**g Municipal Natural Science Foundation (7191003), and the Key Projects of the National Natural Science Foundation of China (81830057).

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Correspondence to Yizhou Yu .

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Liang, K. et al. (2021). Symmetry-Enhanced Attention Network for Acute Ischemic Infarct Segmentation with Non-contrast CT Images. In: de Bruijne, M., et al. Medical Image Computing and Computer Assisted Intervention – MICCAI 2021. MICCAI 2021. Lecture Notes in Computer Science(), vol 12907. Springer, Cham. https://doi.org/10.1007/978-3-030-87234-2_41

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  • DOI: https://doi.org/10.1007/978-3-030-87234-2_41

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