Abstract
The mechanism for the phosphaturia of respiratory acidosis is not well understood because there are concomitant alterations in arterial blood pCO2, pH, bicarbonate and phosphate which could all affect urinary phosphate excretion1–6. Recently, Webb et al1 demonstrated in the rat that alterations in the blood levels of phosphate, bicarbonate and parathyroid hormone could not entirely account for the phosphaturia of respiratory acidosis and concluded that it was the result of a direct effect of the elevated blood pCO2 on renal phosphate transport. Our present clearance and micropuncture experiments were, therefore, designed to reexamine the relationship between blood pCO2 and the phosphaturia of respiratory acidosis.
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References
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© 1980 Plenum Press, New York
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Wen, SF. (1980). Indirect Effect of Hypercapnia on the Phosphaturia of Respiratory Acidosis. In: Massry, S.G., Ritz, E., Jahn, H. (eds) Phosphate and Minerals in Health and Disease. Advances in Experimental Medicine and Biology, vol 128. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-9167-2_14
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DOI: https://doi.org/10.1007/978-1-4615-9167-2_14
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