Abstract
The aim of the study was to give an overview of the mechanism of inhibition of Na+/K+-ATPase activity induced by some specific and non specific inhibitors. For this purpose, the effects of some ouabain like compounds (digoxin, gitoxin), noble metals complexes ([PtCl2DMSO2], [AuCl4]−, [PdCl4]2−, [PdCl(dien)]+, [PdCl(Me4dien)]+), transition metal ions (Cu2+, Zn2+, Fe2+, Co2+), and heavy metal ions (Hg2+, Pb2+, Cd2+) on the activity of Na+/K+-ATPase from rat synaptic plasma membranes (SPM), porcine cerebral cortex and human erythrocytes were discussed.
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Čolović, M., Krstić, D., Krinulović, K. et al. Na+/K+-ATPase: Activity and inhibition. Russ. J. Phys. Chem. 83, 1602–1608 (2009). https://doi.org/10.1134/S0036024409090337
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DOI: https://doi.org/10.1134/S0036024409090337