Log in

Cell-surface expression of the TLR homolog CD180 in circulating cells from splenic and nodal marginal zone lymphomas

  • Letter to the Editor
  • Published:
Leukemia Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Subscribe and save

Springer+ Basic
EUR 32.99 /Month
  • Get 10 units per month
  • Download Article/Chapter or Ebook
  • 1 Unit = 1 Article or 1 Chapter
  • Cancel anytime
Subscribe now

Buy Now

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Figure 1

References

  1. Baseggio L, Traverse-Glehen A, Petinataud F, Callet-Bauchu E, Berger F, Ffrench M et al. CD5 expression identifies a subset of splenic marginal zone lymphomas with higher lymphocytosis: a clinico-pathological, cytogenetic and molecular study of 24 cases. Haematologica 2010; 95: 604–612.

    Article  CAS  Google Scholar 

  2. Swerdlow SH, Campo E, Harris N, Jaffe ES, Pileri SA, Stein H et al World Health Organization Classification of Tumours of Haematopoietic and Lymphoid Tissues. IARC, 2008.

    Google Scholar 

  3. Traverse-Glehen A, Baseggio L, Bauchu EC, Morel D, Gazzo S, Ffrench M et al. Splenic red pulp lymphoma with numerous basophilic villous lymphocytes: a distinct clinicopathologic and molecular entity? Blood 2008; 111: 2253–2260.

    Article  CAS  Google Scholar 

  4. Miguet L, Pacaud K, Felden C, Hugel B, Martinez MC, Freyssinet J-M et al. Proteomic analysis of malignant lymphocyte membrane microparticles using double ionization coverage optimization. Proteomics 2006; 6: 153–171.

    Article  CAS  Google Scholar 

  5. Miguet L, Béchade G, Fornecker L, Zink E, Felden C, Gervais C et al. Proteomic analysis of malignant B-cell derived microparticles reveals CD148 as a potentially useful antigenic biomarker for mantle cell lymphoma diagnosis. J Proteome Res 2009; 8: 3346–3354.

    Article  CAS  Google Scholar 

  6. Miura Y, Miyake K, Yamashita Y, Shimazu R, Copeland NG, Gilbert DJ et al. Molecular cloning of a human RP105 homologue and chromosomal localization of the mouse and human RP105 genes (Ly64 and LY64). Genomics 1996; 38: 299–304.

    Article  CAS  Google Scholar 

  7. Miura Y, Shimazu R, Miyake K, Akashi S, Ogata H, Yamashita Y et al. RP105 is associated with MD-1 and transmits an activation signal in human B cells. Blood 1998; 92: 2815–2822.

    CAS  PubMed  Google Scholar 

  8. Chaplin JW, Kasahara S, Clark EA, Ledbetter JA . Anti-CD180 (RP105) activates B cells to rapidly produce polyclonal Ig via a T cell and MyD88-independent pathway. J Immunol 2011; 187: 4199–4209.

    Article  CAS  Google Scholar 

  9. Porakishvili N, Kulikova N, Jewell AP, Youinou PY, Yong K, Nathwani A et al. Differential expression of CD 180 and IgM by B-cell chronic lymphocytic leukaemia cells using mutated and unmutated immunoglobulin VH genes. Br J Haematol 2005; 131: 313–319.

    Article  CAS  Google Scholar 

  10. Gutiérrez NC, Ocio EM, de Las Rivas J, Maiso P, Delgado M, Fermiñán E et al. Gene expression profiling of B lymphocytes and plasma cells from Waldenström’s macroglobulinemia: comparison with expression patterns of the same cell counterparts from chronic lymphocytic leukemia, multiple myeloma and normal individuals. Leukemia 2007; 21: 541–549.

    Article  Google Scholar 

  11. Kiel MJ, Velusamy T, Betz BL, Zhao L, Weigelin HG, Chiang MY et al. Whole-genome sequencing identifies recurrent somatic NOTCH2 mutations in splenic marginal zone lymphoma. J Exp Med 2012; 209: 1553–1565.

    Article  CAS  Google Scholar 

  12. Rossi D, Trifonov V, Fangazio M, Bruscaggin A, Rasi S, Spina V et al. The coding genome of splenic marginal zone lymphoma: activation of NOTCH2 and other pathways regulating marginal zone development. J Exp Med 2012; 209: 1537–1551.

    Article  CAS  Google Scholar 

Download references

Acknowledgements

This work was supported by research grants from the Institut National du Cancer (INCa PAIR) Lymphome 2008–2011, the Association pour la Recherche en Hématologie Biologique (ARHEB), the Ligue Régionale Contre le Cancer (Comité du Bas-Rhin), the Fondation pour la Recherche Médicale (FRM), the CNRS, the University of Strasbourg UdS, the Région Alsace and the GIS IBiSA. SL was supported by a studentship from the French Ministère de la Recherche. This work is dedicated to the memory of Dr Estelle Zink.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to L Mauvieux.

Ethics declarations

Competing interests

The authors declare no conflict of interest.

Additional information

Supplementary Information accompanies the paper on the Leukemia website

Supplementary information

Rights and permissions

Reprints and permissions

About this article

Cite this article

Miguet, L., Lennon, S., Baseggio, L. et al. Cell-surface expression of the TLR homolog CD180 in circulating cells from splenic and nodal marginal zone lymphomas. Leukemia 27, 1748–1750 (2013). https://doi.org/10.1038/leu.2013.3

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/leu.2013.3

  • Springer Nature Limited

This article is cited by

Navigation