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Survival Rate in Cancer Cervix Patients in a Regional Cancer Centre of South India: A Retrospective Analysis

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The Journal of Obstetrics and Gynecology of India Aims and scope Submit manuscript

Abstract

Context

Carcinoma Cervix is one of the leading prevalent cancers in India especially in rural population and causes a significant mortality. WHO has launched many projects for prevention, screening and treatment plans. Even after many projects, Cervical Cancer persists as a heavy burden public health problem in rural India.

Aims

To calculate survival of cancer cervix patients in a rural population-based RCC and to discuss the factors affecting it.

Methods and Material

A hospital-based gathering of retrospective data of the patients diagnosed with carcinoma cervix over 5 years from January 2013 to December 2017 (single institution analysis). We included 751 patient’s data from our cancer registry for analysis. Data related to demographics, treatment and follow up records were taken and statistical analysis done.

Results

The survival rates were 64.0%, 50.0%, 36.9% and 17.5% for Stage I, Stage II, Stage III and Stage IV, respectively. The best survival outcomes were for those treated with only surgery. Involvement of nodes had poor survival than those with no involvement. Various patient-related factors like Religion, Education and Marital status are found to be non-significant factors even-though they have survival differences. STAGE of the disease emerged as a significant prognostic factor.

Conclusion

Our study concluded that higher stage and nodal involvement had poor outcomes and also lower survival compared to Western and Indian literature. We should also address all the socio-economic factors that affects survival. Randomized prospective studies are needed to evaluate the effect of socio-economic factors on survival.

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References

  1. Hyuna S, Jacques F, Rebecca LS, Mathieu L, Isabelle S, Ahmedin J. GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries. CA Cancer J Clin. 2021;71(3):209–49.

    Article  Google Scholar 

  2. https://gco.iarc.fr/today/data/factsheets/populations/356-india-fact-sheets. The Global Cancer Observatory, IARC

  3. Federico C, Alleyn J, Dola C, et al. Relationship among age, race, medical funding, and cervical cancer survival. J Natl Med Assoc. 2010;102:199–205.

    PubMed  Google Scholar 

  4. Sankaranarayanan R, Swaminathan R. Cancer Survival in Africa, Asia, the Carribbean and Central America. IARC Scientific Publications No. 162. Lyon: International Agency for Research on Cancer; 2011.

  5. Kaku M, Mathew A, Rajan B. Impact of socio-economic factors in delayed reporting and late-stage presentation among patients with cervix cancer in a major cancer hospital in South India. Asian Pac J Cancer Prev. 2008;9(4):589–94.

    PubMed  Google Scholar 

  6. Balasubramaniam G, Gaidhani R, Khan A, Saoba S, Mahantshetty U, Maheshwari A. Survival rate of cervical cancer from a study conducted in India. Indian J Med Sci. 2020;73:1–10.

    Google Scholar 

  7. Ferlay J, Shin HR, Bray F, Forman D, Mathers C, Parkin DM. GLOBOCAN 2008 Cancer Incidence and Mortality Worldwide: IARC Cancer Base No. 10 Lyon, France: International Agency for Research on Cancer; 2010

  8. Coker AL, Du XL, Fang S, Eggleston KS. Socioeconomic status and cervical cancer survival among older women: findings from the SEER-Medicare linked data cohorts. Gynecol Oncol. 2006;102(2):278–84.

    Article  PubMed  Google Scholar 

  9. Nandakumar A, Anantha N, Venugopal TC. Incidence, mortality and survival in cancer of the cervix in Bangalore. India Br J Cancer. 1995;71(6):1348–52.

    Article  CAS  PubMed  Google Scholar 

  10. Munagala R, Rai SN, Ganesharajah S, Bala N, Gupta RC. Clinicopathological, but not socio-demographic factors affect the prognosis in cervical carcinoma. Oncol Rep. 2010;24(2):511–20.

    PubMed  Google Scholar 

  11. Coker AL, Du XL, Fang S, Eggleston KS. Socioeconomic status and cervical cancer survival among older women: findings from the SEER-Medicare linked data cohorts. Gynecol Oncol. 2006;102(2):278–84.

    Article  PubMed  Google Scholar 

  12. Sankaranarayanan R, Nair MK, Jayaprakash PG, Stanley G, Varghese C, Ramadas V, Padmakumary G, et al. Cervical cancer in Kerala: a hospital registry-based study on survival and prognostic factors. Br J Cancer. 1995;72(4):1039–42.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  13. Yeole BB, Sankaranarayanan R, Jussawalla DJ. Long-term survival from uterine cervical cancer in Mumbai (Bombay). India Int J Cancer. 1998;78:394–5.

    Article  CAS  PubMed  Google Scholar 

  14. Sriamporn S, Black RJ, Sankaranarayanan R, Kamsa-Ad S, Parkin DM, Vatanasapt V. Cancer survival in Khon Kaen Province. Thailand Int J Cancer. 1995;61:296–300.

    Article  CAS  PubMed  Google Scholar 

  15. Sankaranarayanan R, Swaminathan R, Black RJ. Global variations in cancer survival, Study group on cancer survival in develo** countries. Cancer. 1996;78:2461–4.

    Article  CAS  PubMed  Google Scholar 

  16. Jayant K, Rao RS, Nene BM, Dale PS, Nandakumar A. Improved survival in cervical cancer cases in a rural Indian population. Br J Cancer. 1996;74:285–7.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  17. Thulaseedharan JV, Malila N, Swaminathan R, Esmy PO, Hakama M, Muwonge R, et al. Survival of patients with cervical cancer in rural India. J Clin Gynecol Obstetr. 2015;4:290–6.

    Article  Google Scholar 

  18. Singh M, Jha RP, Shri N, et al. Secular trends in incidence and mortality of cervical cancer in India and its states, 1990–2019: data from the Global Burden of Disease 2019 Study. BMC Cancer. 2022;22:149. https://doi.org/10.1186/s12885-022-09232-w.

    Article  PubMed  PubMed Central  Google Scholar 

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Authors and Affiliations

  1. Department of Surgical Oncology, Govt Arignar Anna Memorial Cancer Hospital and Research Institute-Regional Cancer Centre, Karapettai, Kanchipuram, Tamilnadu, India

    Sakthi Usha Devi Jeevarajan, Prasanna Srinivasa Rao Harikrishnan, T. D. Balamurugan & Ajay Kumar Arunachalam

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  1. Sakthi Usha Devi Jeevarajan
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  2. Prasanna Srinivasa Rao Harikrishnan
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  3. T. D. Balamurugan
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  4. Ajay Kumar Arunachalam
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Contributions

SUD, PSR and TDB was involved in data collection, design, manuscript editing and manuscript review the manuscript, SUD, PSR, TDB and AK were involved in definition of intellectual content, literature search, clinical studies, experimental studies, data acquisition, data analysis, manuscript preparation the manuscript, PSR, TDB and AK was involved in statistical analysis.

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Correspondence to Sakthi Usha Devi Jeevarajan.

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The authors declare that there are NO conflicts of interest. The authors whose names are listed immediately below certify that they have NO affiliations with or involvement in any organization or entity with any financial interest (such as honoraria; educational grants; participation in speakers’ bureaus; membership, employment, consultancies, stock ownership, or other equity interest; and expert testimony or patent-licensing arrangements), or non-financial interest (such as personal or professional relationships, affiliations, knowledge or beliefs) in the subject matter or materials discussed in this manuscript.

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Dr. Sakthi Usha Devi J, MD (OG), MCH (Surgical Oncology), DNB (Surgical Oncology), Associate Professor. Dr. Prasanna Srinivasa Rao H, M.S, MCH, (Surgical Oncology), Assistant Professor. Dr. T D Balamurugan, M.S, MCH (Surgical Oncology), DRNB (Surgical Oncology), Assistant Professor. Dr. Ajay Kumar A, MCH Post Graduate (Surgical Oncology).

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Jeevarajan, S.U.D., Harikrishnan, P.S.R., Balamurugan, T.D. et al. Survival Rate in Cancer Cervix Patients in a Regional Cancer Centre of South India: A Retrospective Analysis. J Obstet Gynecol India 73, 414–420 (2023). https://doi.org/10.1007/s13224-023-01843-y

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  • DOI: https://doi.org/10.1007/s13224-023-01843-y

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