Abstract
This paper reports the selective and sensitive voltammetric determination of l-cysteine in the presence of folic acid using ethynylferrocene modified carbon nanotubes paste electrode in 0.1 M phosphate buffer solution (pH 7.0). Using square wave voltammetry, we could measure l-cysteine and folic acid in one mixture independently from each other by a potential difference of about 410 mV for the first time. Square wave voltammetric peak current of l-cysteine and folic acid increased linearly with their concentrations in the ranges of 0.2–250.0 and 1.0–500.0 μmol L−1, respectively. The detection limits of 0.07 and 0.6 μmol L−1 were achieved for l-cysteine and folic acid, respectively. The proposed voltammetric sensor was successfully applied to the determination of l-cysteine and folic acid in real samples.
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Yosypchuk B, Novotny I (2002) Talanta 56:971
Ensafi AA, Dadkhah-Tehrani S, Karimi-Maleh H (2011) Anal Sci 27:409
Dumonceaux J, Goujon C, Joliot V, Briand P, Hazan U (2001) J Virol 75:5425
Schrynemackers-Pitance P, Schoos-Berbette S (1987) Clin Chim Acta 166:91
Chwatko G, Bold E (2000) Talanta 52:509
Gupta VK, Singh AK, Gupta B (2006) Anal Chim Acta 575:198
Goyal RN, Gupta VK, Chatterjee S (2009) Biosens Bioelec 24:3562
Goyal RN, Gupta VK, Chatterjee S (2009) Biosens Bioelec 24:1649
Prasad R, Gupta VK, Kumar A (2004) Anal Chim Acta 508:61
Jain R, Gupta VK, Jadon N, Radhapyari K (2010) J Electroanal Chem 648:20
Jain R, Gupta VK, Jadon N, Radhapyari K (2010) Anal Biochem 407:79
Gupta VK, Jain AK, Singh LP, Khurana U (1997) Anal Chim Acta 355:33
Al-Shammary FJ, Al-Rashood KA, Mian NA, Mian MS (1990) Anal Profiles Drug Sub 19:221
Nelson BC, Sharpless KE, Sander LC (2006) J Chromatogr A 1135:203
Rodriguez-Bernaldo de Quiros A, Castro de Ron C, Lopez-Hernandez J, Lage-Yusty MA (2004) J Chromatogr A 1032:135
Zhaoa SL, Yuan HY, **e C, **ao D (2006) J Chromatogr A 1107:290
**ao F, Ruan C, Liu L, Yan R, Zhao F, Zeng B (2008) Sens Actuators B 134:895
Ensafi AA, Karimi-Maleh H (2010) J Electroanal Chem 640:75
Zhang B, Zhao L, Lin JM (2008) Talanta 74:1154
Hrůza Z, Hlaváčková V, Babický A (1966) Exp Geron 2:9
http://www.jbc.org/content/189/2/651.full.pdf. Accessed 13 July 2012
Iijima S (1991) Nature 354:56
Goyal RN, Oyama M, Gupta VK, Singh SP, Sharma RA (2008) Sens Actuators B 134:816
Ajayan PM (1999) Chem Rev 99:787
Wang GX, Ahn J, Yao J, Lindsay M, Liu HK, Dou SX (2003) J Pow Sour 119:160
Che G, Lakshmi BB, Martin CR, Fisher EE (1999) Langmuir 15:750
Ensafi AA, Izadi M, Karimi-Maleh H (2012) Ionics. doi:10.1007/s11581-012-0705-0
Dai H, Hafner H, Rinzler AG, Colbert DT, Smalley RE. Nature 384:147
Khalilzadeh MA, Khaleghi F, Gholami F, Karimi-Maleh H (2009) Anal Lett 42:584
Afzali D, Karimi-Maleh H, Khalilzadeh MA (2011) Environ Chem Lett 9:375
Goyal RN, Gupta VK, Chatterjee S (2010) Sens Actuators B 149:252
Goyal RN, Gupta VK, Chatterjee S (2008) Talanta 76:662
Khalilzadeh MA, Karimi-Maleh H (2010) Anal Lett 43:186
Karimi-Maleh H, Ensafi AA, Beitollahi H, Nasiri V, Khalilzadeh MA, Biparva P (2012) Ionics 18:687
Asnaashariisfahani M, Karimi-maleh H, Ahmar H, Ensafi AA, Fakhari AR, Khalilzadeh MA, Karimi F (2012) Anal Meth. doi:10.1039/c2ay25418b
Ensafi AA, Karimi-Maleh H, Mallakpour S, Hatami M (2011) Sens Actuators B 155:464
Ensafi AA, Karimi-Maleh H, Mallakpour S, Rezaei B (2011) Coll Surf B 87:480
Khalilzadeh MA, Karimi-Maleh H, Amiri A, Gholami F, Motaghed mazhabi R (2010) Chin Chem Lett 21:1467
Galus Z (1976) Fundumentals of electrochemical analysis. Ellis Horwood, New York
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The authors wish to thank the Science and Research Branch, Islamic Azad University, Mazandaran for the support.
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Kazemi, S., Karimi-Maleh, H., Hosseinzadeh, R. et al. Selective and sensitive voltammetric sensor based on modified multiwall carbon nanotubes paste electrode for simultaneous determination of l-cysteine and folic acid. Ionics 19, 933–940 (2013). https://doi.org/10.1007/s11581-012-0816-7
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DOI: https://doi.org/10.1007/s11581-012-0816-7