Abstract
Ganoderma have been regarded as a traditional source of natural bioactive compounds for centuries and have recently been exploited for potential components in the cosmetics industry. Besides Ganoderma polysaccharides and triterpenes, multiple proteins have been found in Ganoderma. With the in-depth study of these proteins, various pharmacological functions of Ganoderma have become important in the discovery and development of new products. In the review, we summarized and discussed the kinds and characteristics of Ganoderma proteins, especially on fungal immunomodulatory proteins (FIPs) which can be potentially developed into cosmeceuticals or nutricosmetics and are a suitable target for production using established biotechnological methods. Furthermore, we discuss their pharmacological activities of the proteins with a focus on their pharmacological functions related to cosmetics, such as antioxidant activity, inhibition of melanin, antibacterial activity, and regulation of inflammatory mediators. Numerous other questions also are addressed before the proteins can be widely accepted and used as cosmetic additives.
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The author would like to acknowledge director ** to make a patent transformation for producing a Ganoderma protein cosmetic sample in the Qinling Health Medicine Industrial Technology Co., Ltd.
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This research was financially supported by Grant 19H100000393 from the Fujian Puzhiyun Biological Technology Co., Ltd.
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Li, LD., Mao, PW., Shao, KD. et al. Ganoderma proteins and their potential applications in cosmetics. Appl Microbiol Biotechnol 103, 9239–9250 (2019). https://doi.org/10.1007/s00253-019-10171-z
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DOI: https://doi.org/10.1007/s00253-019-10171-z