Search
Search Results
-
The effect of human recombinant epidermal growth factor on capsule contraction in an irradiated rat model
BackgroundBreast implants are commonly used in plastic surgery for aesthetic and reconstructive purposes. One of the most important complications of...
-
Efficient expression of fusion human epidermal growth factor in tobacco chloroplasts
BackgroundChloroplast transformation is a robust technology for the expression of recombinant proteins. Various types of pharmaceutical proteins...
-
The effect of recombinant human epidermal growth factor on radiation dermatitis in rectal and anal cancer patients: a self-controlled study
BackgroundOur previous study reported that recombinant human epidermal growth factor (rhEGF)-triggered EGFR internalization promoted radioresistance....
-
Utilization of Freeze-Thawing Method for High-level Expression of Functional Human Epidermal Growth Factor (hEGF)
The wide applications of human epidermal growth factor (hEGF) as an efficient mitogen agent in the clinical, health, and cosmetic industries has made...
-
Epidermal Growth Factor (EGF) in Wound Repair
Growth factors are vital for regulating many of our cellular processes. Growth factors classically act as signalling...
-
Economic optimization of expression of soluble human epidermal growth factor in Escherichia coli
Human epidermal growth factor (hEGF) has multiple biological functions, such as promoting cell proliferation, differentiation, and migration. In...
-
Growth Factor Therapy
Many of chronic wounds are delayed or fail to heal through conventional treatment because attenuated activities of cells responsible for wound...
-
Membrane protease prostasin promotes insulin secretion by regulating the epidermal growth factor receptor pathway
Prostasin (PRSS8) is a serine protease that metabolizes and moderates the effect of specific substrates. Epidermal growth factor receptor (EGFR),...
-
Enhancement of recombinant human keratinocyte growth factor 1 protein production in transgenic hazelnut (Corylus avellana L.) plant cell suspension cultures under RAmy3D inducible promoter
Recombinant human KGF1 (rhKGF) is a fibroblast growth factor that promotes epidermal cell proliferation, differentiation, migration, and wound...
-
Design and construction of scFv-PE35KDEL as a novel immunotoxin against human epidermal growth factor receptor 2 for cancer therapy
ProposeHuman epidermal growth factor receptor 2 (HER2) is overexpressed on the surface of some kinds of cancer cells including breast cancer. In this...
-
Hyaluronic acid-based biodegradable microneedles loaded with epidermal growth factor for treatment of diabetic foot
Pain relief and effective methods of treating patients with diabetic foot wounds have yet to be established. Improved surgical treatment, other than...
-
A pharmacokinetic study to comparatively evaluate the bioequivalence and safety of a humanized recombinant monoclonal antibody targeting human epidermal growth factor receptor-2 with the reference Herceptin in healthy Chinese subjects
Purpose . This study aimed to compare the safety, tolerability, pharmacokinetics (PK), and bioequivalence of a test humanized recombinant monoclonal...
-
Identification of myeloid-derived growth factor as a mechanically-induced, growth-promoting angiocrine signal for human hepatocytes
Recently, we have shown that after partial hepatectomy (PHx), an increased hepatic blood flow initiates liver growth in mice by vasodilation and...
-
Recombinant human epidermal growth factor combined with vacuum sealing drainage for wound healing in Bama pigs
BackgroundVacuum sealing drainage (VSD) and epidermal growth factor (EGF) both play an important role in the treatment of wounds. This study aims to...
-
Rational Design and Production of Bioactive Analogs of Recombinant Human Keratinocyte Growth Factor (rhKGF) with Reduced Aggregation Propensity
Recombinant human keratinocyte growth factor (rhKGF) is a highly aggregation-prone therapeutic protein. The present study aimed to reduce aggregation...
-
A toolkit for recombinant production of seven human EGF family growth factors in active conformation
Epidermal growth factors (EGF) play a wide range of roles in embryogenesis, skin development, immune response homeostasis. They are involved in...
-
Rapid Screening for High Expressing Multicopy Recombinants and Enhanced Epidermal Growth Factor (EGF) Protein Production Using Pichia Pastoris
Epidermal growth factor (EGF) is a highly effective stimulator which promotes cell proliferation and this has led it to being proposed as a...
-
Mechanistic investigation into selective cytotoxic activities of gold nanoparticles functionalized with epidermal growth factor variants
Epidermal growth factor (EGF) gains unique selective cytotoxicity against cancer cells upon conjugation with gold nanoparticles (GNPs). We have...
-
Electrochemical Biosensors for Soluble Epidermal Growth Factor Receptor Detection
Simple detection of oncomarkers is of paramount importance in cancer diagnosis. Screen-printed carbon electrodes (SPCEs) were modified by...
-
Milk fat-globule epidermal growth factor 8: A potential Regulator of Cutaneous Wound Healing
Destroying the integrity of the skin may causes disability and even death from injury or illness. Wound healing is a core mechanism to maintain skin...
