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A transcriptome based molecular classification scheme for cholangiocarcinoma and subtype-derived prognostic biomarker
Previous studies on the molecular classification of cholangiocarcinoma (CCA) focused on certain anatomical sites, and disregarded tissue...
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Copeptin: a novel prognostic biomarker in trauma: a review article
BackgroundTrauma has a significant impact on the overall health of individuals worldwide, being a leading cause of morbidity and mortality with...
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Prognostic biomarker discovery based on proteome landscape of Chinese lung adenocarcinoma
Despite recent innovations in imaging and genomic screening promotes advance in diagnosis and treatment of lung adenocarcinoma (LUAD), there remains...
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Serum IGFBP-1 as a promising diagnostic and prognostic biomarker for colorectal cancer
Our previous study showed that levels of circulating insulin-like growth factor binding protein-1 (IGFBP-1) has potential diagnostic value for...
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Prognostic utility of a multi-biomarker panel in patients with suspected myocardial infarction
BackgroundThe accurate identification of patients with high cardiovascular risk in suspected myocardial infarction (MI) is an unmet clinical need....
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SAMD13 serves as a useful prognostic biomarker for hepatocellular carcinoma
Hepatocellular carcinoma (HCC) is the most common form of liver cancer and the 5-year relative overall survival (OS) rate is less than 20%. Since...
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Transcriptome analysis revealed SMURF2 as a prognostic biomarker for oral cancer
BackgroundThe activation of TGF-β pathway can facilitate tumorigenesis. Understanding the TGF-related genes (TRGs) in oral cancer and determining...
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SPON1 is an independent prognostic biomarker for ovarian cancer
BackgroundOvarian cancer has the worst outcome among gynecological malignancies; therefore, biomarkers that could contribute to the early diagnosis...
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FAR Ratio as Prognostic Biomarker in AMI
Acute mesenteric ischemia (AMI) is a vascular emergency resulting from decreased blood flow caused by the occlusion of the mesenteric vessels,...
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EMP3 as a prognostic biomarker correlates with EMT in GBM
BackgroundGlioblastoma (GBM) is the most aggressive malignant central nervous system tumor with a poor prognosis.The malignant transformation of...
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Integrated profiling identifies CACNG3 as a prognostic biomarker for patients with glioma
Gliomas are the most common malignant primary brain tumors in adults with poor prognoses. The purpose of this study is to explore CACNG3 as a...
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Challenges facing the clinical adoption of a new prognostic biomarker: a case study
In this article, we show how a particular biomarker comes into being in an emergency department in a hospital in Copenhagen, Denmark. We explore the...
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TIPARP as a prognostic biomarker and potential immunotherapeutic target in male papillary thyroid carcinoma
BackgroundMale patients with papillary thyroid carcinoma (PTC) tend to have poorer prognosis compared to females, partially attributable to a higher...
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Platelet-to-albumin ratio and radiation-induced lymphopenia—prognostic biomarker for carcinoma esophagus
BackgroundEsophageal cancer has a poor survival outcome with 5-year OS at 16.7% despite treatment. Some inflammation-based prognostic indicators like...
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Pan-cancer analysis identifies RNF43 as a prognostic, therapeutic and immunological biomarker
BackgroundRING finger protein 43 (RNF43), an E3 ubiquitin ligase, is a homologous gene mutated in several cancers. However, the pan-cancer panoramic...
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Osteopontin is a prognostic circulating biomarker in patients with neuroendocrine neoplasms
PurposeOsteopontin (OPN), also called secreted phosphoprotein 1 (SPP1) is a matricellular glycoprotein whose expression is elevated in various types...
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SLMO2 is a potential prognostic and immunological biomarker in human pan-cancer
SLMO2 is a lipid transporter that transports phosphatidylserine to the interior of mitochondria, also known as PRELID3B, which plays an important...
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FBP1 is a potential prognostic biomarker and correlated with tumor immunosuppressive microenvironment in glioblastoma
Hypoxia has been shown to contribute to tumor immunosuppressive microenvironment and is an effective prognostic indicator. This study aimed to screen...
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LENG8-AS1: A Prognostic Biomarker in Colorectal Cancer-Differential Expression and Clinical Implications
Colorectal cancer (CRC) manifests as a prevalent malignancy marked by distinct gene expression patterns. In the intricate landscape of cancer...
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Choroidal hypertransmission width on optical coherence tomography: a prognostic biomarker in idiopathic macular hole surgery
PurposeTo test the hypothesis that optical coherence tomography (OCT) choroidal hypertransmission width (CHW) is a prognostic biomarker in idiopathic...