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Correlating Reiff scores with clinical, functional, and prognostic factors: characterizing noncystic fibrosis bronchiectasis severity: validation from a nationwide multicenter study in Taiwan
BackgroundOur study aimed to confirm a simplified radiological scoring system, derived from a modified Reiff score, to evaluate its relationship with...
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Smoking accelerates renal cystic disease and worsens cardiac phenotype in Pkd1-deficient mice
Smoking has been associated with renal disease progression in ADPKD but the underlying deleterious mechanisms and whether it specifically worsens the...
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Glis2 is an early effector of polycystin signaling and a target for therapy in polycystic kidney disease
Mouse models of autosomal dominant polycystic kidney disease (ADPKD) show that intact primary cilia are required for cyst growth following the...
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Ppia is the most stable housekee** gene for qRT-PCR normalization in kidneys of three Pkd1-deficient mouse models
Autosomal Dominant Polycystic Kidney Disease (ADPKD) is the most common inherited renal disorder, characterized by renal cyst development leading to...
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PKD1 and PKD2 mRNA cis-inhibition drives polycystic kidney disease progression
Autosomal dominant polycystic kidney disease (ADPKD), among the most common human genetic conditions and a frequent etiology of kidney failure, is...
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Clinical characteristics and drug susceptibility profiles of Mycobacterium abscessus complex infection at a medical school in Thailand
ObjectivesThis study investigated the differences in epidemiological and clinical data, and antimicrobial susceptibilities among different subspecies...
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Genetic Kidney Disorders: An Algorithmic Approach
This video provides an algorithm covering the etiologies, diagnosis, and treatment approaches utilized in the management of genetic kidney disorders.
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Smoking status, cadmium, and chronic kidney disease
BackgroundChronic kidney disease (CKD) affects 10% of the general population in Western countries. Currently, CKD cannot be cured and there are only...
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Renal plasticity revealed through reversal of polycystic kidney disease in mice
Initiation of cyst formation in autosomal dominant polycystic kidney disease (ADPKD) occurs when kidney tubule cells are rendered null for either PKD1 ...
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The First Data on Larvae of Trematodes from the Gastropod Hydrobia acuta in the Black Sea
AbstractIn this work, the first information on the species biodiversity of larvae of trematodes in the gastropod Hydrobia acuta is provided. As...
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Atypical lipoma of the right piriformis muscle: a case report and review of the literature
BackgroundPiriformis muscle mass is rare, which is particular for intrapiriformis lipoma. Thus far, only 11 cases of piriformis muscle mass have been...
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Imaging Findings of Perinatal Brain Injury that May Cause Cerebral Palsy
With the advances and widespread use of equipment, MRI has become the first choice for diagnostic imaging of central nervous system diseases in...
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Clinical characteristics of patients with bronchiectasis with nontuberculous mycobacterial disease in Mainland China: a single center cross-sectional study
BackgroundThe diagnosis and treatment of patients with bronchiectasis and nontuberculous mycobacterium (NTM) pulmonary disease are challenging issues...
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Macrolides and Asthma Therapy
Asthma is a chronic condition of the airways that is typified by bronchial hyperresponsiveness, variable airflow obstruction, and airway...
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Global phylogenomic analyses of Mycobacterium abscessus provide context for non cystic fibrosis infections and the evolution of antibiotic resistance
Mycobacterium abscessus (MAB) is an emerging pathogen that leads to chronic lung infections. To date, the global population structure of non-cystic...
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Dandy–Walker malformation and variants: clinical features and associated anomalies in 28 affected children—a single retrospective study and a review of the literature
ObjectiveTo investigate the clinical characteristics, the neuroimaging features and associated anomalies observed in children affected by...
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Recent Investigations on Neurotransmitters’ Role in Acute White Matter Injury of Perinatal Glia and Pharmacotherapies—Glia Dynamics in Stem Cell Therapy
Periventricular leukomalacia (PVL) and cerebral palsy are two neurological disease conditions developed from the premyelinated white matter ischemic...
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Emerging magnetic resonance imaging techniques in open spina bifida in utero
Magnetic resonance imaging (MRI) has become an essential diagnostic modality for congenital disorders of the central nervous system. Recent...
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Tumor size measurements of pancreatic cancer with neoadjuvant therapy based on RECIST guidelines: is MRI as effective as CT?
ObjectivesTo compare tumor size measurements using CT and MRI in pancreatic cancer (PC) patients with neoadjuvant therapy (NAT).
Methods ...