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1. miR-124-3p and miR-194-5p regulation of the PI3K/AKT pathway via ROR2 in medulloblastoma progression

   Medulloblastoma (MB), a prevalent pediatric central nervous system tumor, is influenced by microRNAs (miRNAs) that impact tumor initiation and...

   Chen Wang, Runxi Fu, ... Chenran Zhang in Cancer Gene Therapy

   Article Open access 19 March 2024
   

2. Unveiling the protective effects of BMSCs/anti-miR-124-3p exosomes on LPS-induced endometrial injury

   Researchers have reported that miR-124-3p is highly expressed in patients with chronic endometritis. However, the underlying mechanism of miR-124-3p...

   Yihong Chen, Shan Zheng, ... Juanbing Wei in Functional & Integrative Genomics

   Article 16 February 2024
   

3. MiR-124-3p negatively impacts embryo implantation via suppressing uterine receptivity formation and embryo development

   During embryo implantation, blastocyst interacts with the receptivity endometrium and the endometrial epithelium secretes nurturing fluid to support...

   Kezhen Yao, Quanmin Kang, ... **aofen ** in Reproductive Biology and Endocrinology

   Article Open access 31 January 2024
   

4. MiR-124-3p inhibits tumor progression in prostate cancer by targeting EZH2

   Prostate cancer (PCa) is widespread cancer with significant morbidity and mortality rates. MicroRNAs (miRNAs) have been identified as important...

   Bao-feng Song, Li-zhe Xu, ... Fan Cheng in Functional & Integrative Genomics

   Article Open access 08 March 2023
   

5. Knockdown of lncRNA MALAT1 attenuates renal interstitial fibrosis through miR-124-3p/ITGB1 axis

   Renal interstitial fibrosis (RIF) considered the primary irreversible cause of chronic kidney disease. Recently, accumulating studies demonstrated...

   Wei** **a, **ang Chen, ... Zhi Chen in Scientific Reports

   Article Open access 23 October 2023
   

6. Molecular Mechanisms Involved in the Regulation of Neurodevelopment by miR-124

   miR-124 is a miRNA predominantly expressed in the nervous system and accounts for more than a quarter of the total miRNAs in the brain. It regulates...

   ** Gu, **aona Xu, ... Jiawei Chen in Molecular Neurobiology

   Article 25 February 2023
   

7. CircHIPK3/miR-124 affects angiogenesis in early-onset preeclampsia via CPT1A-mediated fatty acid oxidation

   Abstract

   Multiple theories have been proposed to explain the pathogenesis of early-onset preeclampsia (EOPE), and angiogenic dysfunction is an...

   Yanying Wu, **grui Huang, ... Qi Li in Journal of Molecular Medicine

   Article 21 June 2024
   

8. M2 Microglia-Derived Exosomes Protect Against Glutamate-Induced HT22 Cell Injury via Exosomal miR-124-3p

   As one of the most serious complications of sepsis, sepsis-associated encephalopathy has not been effectively treated or prevented. Exosomes, as a...

   Lan Zhu, Limei Ma, ... Gaofeng Zhang in Molecular Neurobiology

   Article Open access 04 March 2024
   

9. miR-124-3p downregulates EGR1 to suppress ischemia-hypoxia reperfusion injury in human iPS cell-derived cardiomyocytes

   Ischemic heart diseases are a major global cause of death, and despite timely revascularization, heart failure due to ischemia-hypoxia reperfusion...

   Qiaoke Yang, Kozue Murata, ... Hidetoshi Masumoto in Scientific Reports

   Article Open access 27 June 2024
   

10. MDMA targets miR-124/MEKK3 via MALAT1 to promote Parkinson’s disease progression

    Background

    Parkinson’s disease (PD) is a well-known neurodegenerative disease that is usually caused by the progressive loss of dopamine neurons and...

    **n Geng, Shipeng Li, ... Hualin Yu in Molecular Biology Reports

    Article Open access 09 September 2023
    

11. Effect of Oxygen–Glucose Deprivation of Microglia-Derived Exosomes on Hippocampal Neurons: A Study on miR-124 and Inflammatory Cytokines

    Stroke is a cerebrovascular disease that threatens human health. Develo** safe and effective drugs and finding therapeutic targets has become an...

    Yizhen Zhu, Xue Zhao, ... Guo Ge in Journal of Molecular Histology

    Article 10 April 2024
    

12. miR-124-3p target genes identify globus pallidus role in suicide ideation recovery in borderline personality disorder

    Borderline personality disorder (BPD) is characterized by patterns of unstable affect, unstable interpersonal relationships, and chronic suicidal...

    Macarena S. Aloi, Guillermo F. Poblete, ... Ramiro Salas in npj Mental Health Research

    Article Open access 05 June 2023
    

13. miR-124-3p regulates the proliferation and differentiation of retinal progenitor cells through SEPT10

    Retinal degenerative diseases such as glaucoma, retinitis pigmentosa, and age-related macular degeneration pose serious threats to human visual...

    Bingqiao Shen, Huiqin Gao, ... Yisheng Zhong in Cell and Tissue Research

    Article 21 February 2023
    

14. The mechanism of lncRNA MALAT1 targeting the miR-124-3p/IGF2BP1 axis to regulate osteogenic differentiation of periodontal ligament stem cells

    Objectives

    This study aimed to investigate the regulatory roles of lncRNA MALAT1, miR-124-3p, and IGF2BP1 in osteogenic differentiation of periodontal...

    Nan Gu, Yao Wang, ... Zhihui Liu in Clinical Oral Investigations

    Article 16 March 2024
    

15. Rosuvastatin attenuates total-tau serum levels and increases expression of miR-124-3p in dyslipidemic Alzheimer's patients: a historic cohort study

    microRNAs are candidate diagnostic biomarkers for Alzheimer's disease. This study aimed to compare Silymarin with Rosuvastatin and placebo on...

    Farnoosh Usefi, Auob Rustamzadeh, ... Fatemeh Moradi in Metabolic Brain Disease

    Article 19 June 2024
    

16. Elabela, a Novel Peptide, Exerts Neuroprotective Effects Against Ischemic Stroke Through the APJ/miR-124-3p/CTDSP1/AKT Pathway

    Elabela (ELA), which is the second endogenous peptide ligand of the apelin receptor (APJ) to be discovered, has been widely studied for potential use...

    Kang-long Zhang, Shuang-mei Li, ... Tong Wang in Cellular and Molecular Neurobiology

    Article Open access 27 April 2023
    

17. The relationship between DNA methyltransferase 3B (DNMT3B) and miR 124-3pa expressions in bladder cancer tissues

    Background

    Cancer bladder is the most common malignant tumor affecting the urinary tract. Genetic alterations are tightly associated with the...

    Mohammed S. Fawzy, Abdel Rahman M. El Faiomy, ... Samia Hussein in Molecular Biology Reports

    Article 30 October 2023
    

18. Increased miR-124-3p alleviates type 2 inflammatory response in allergic rhinitis via IL-4Rα

    Background and objectives

    miRNAs play a crucial role in regulating immune responses. However, the effect of miR-124-3p on type 2 inflammation in...

    Qian Liu, Yang Shen, ... Guolin Tan in Inflammation Research

    Article Open access 03 August 2022
    

19. miR-124-3p sabotages lncRNA MALAT1 stability to repress chondrocyte pyroptosis and relieve cartilage injury in osteoarthritis

    Background

    Osteoarthritis (OA) is a prevalent inflammatory joint disorder. microRNAs (miRNAs) are increasingly involved in OA.

    Aim

    Our study is...

    Rigbat Rozi, Yubo Zhou, ... **bo Chen in Journal of Orthopaedic Surgery and Research

    Article Open access 15 October 2022
    

20. miR-124 regulates early isolation-induced social abnormalities via inhibiting myelinogenesis in the medial prefrontal cortex

    Patients with autism spectrum disorder (ASD) typically experience substantial social isolation, which may cause secondary adverse effects on their...

    Yanli Zhang, Yingting Pang, ... Ming **ao in Cellular and Molecular Life Sciences

    Article 04 September 2022