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1. Local Mechano-Dependent Calcium Influx Controls the Activity of Calcium-Dependent Potassium Channels of Big and Small Conductance in Human Lymphoma Cells

   Abstract

   Burkitt’s lymphoma is an aggressive and fast-growing form of non-Hodgkin’s lymphoma with the highest invasive potential of all types of...

   V. Y. Vasileva, V. I. Chubinskiy-Nadezhdin in Cell and Tissue Biology

   Article 17 April 2022
   

2. Global and Local Regulation of Neuronal Differentiation by Calcium Transients

   Embryonic spinal neurons express ion channels prior to synaptogenesis that mediate specialized forms of excitability promoting Ca 2+ influx. Ca 2+...

   Nicholas C. Spitzer in Understanding Calcium Dynamics

   Chapter
   

3. Intestinal Piezo1 aggravates intestinal barrier dysfunction during sepsis by mediating Ca²⁺ influx

   Introduction

   Intestinal barrier dysfunction is a pivotal factor in sepsis progression. The mechanosensitive ion channel Piezo1 is associated with...

   Zimeng Yan, Lei Niu, ... Shuming Pan in Journal of Translational Medicine

   Article Open access 04 April 2024
   

4. STIM1-Orai1 interaction mediated calcium influx activation contributes to cardiac contractility of insulin-resistant rats

   Purpose

   Metabolic syndrome (MetS) became a tremendous public health burden in the last decades. Store-operated calcium entry (SOCE) is a unique...

   Aysegul Durak, Yusuf Olgar, ... Belma Turan in BMC Cardiovascular Disorders

   Article Open access 05 April 2022
   

5. Increased Calcium Influx through L-Type Calcium Channels in Hippocampal Neurons with Exogenous Expression of Presenilin-1 ΔE9 Mutant

   Mutations in the PSEN1 gene encoding presenilin-1 (PS1) protein are the most common cause of familial Alzheimer’s disease. One of these, deletion of...

   K. V. Skobeleva, М. A. Ryazantseva, Е. V. Kaznacheyeva in Bulletin of Experimental Biology and Medicine

   Article 01 April 2022

6. Molecular recording of calcium signals via calcium-dependent proximity labeling

   Calcium ions serve as key intracellular signals. Local, transient increases in calcium concentrations can activate calcium sensor proteins that in...

   J. Wren Kim, Adeline J. H. Yong, ... Nicholas T. Ingolia in Nature Chemical Biology

   Article 24 April 2024
   

7. Modeling Calcium Waves

   We present an introduction to the mathematics of calcium waves, both intracellular and intercellular. After a discussion of the earlier models I...

   James Sneyd, Krasimira Tsaneva-Atanasova in Understanding Calcium Dynamics

   Chapter
   

8. Cell-surface photochemistry mediated calcium overload for synergistic tumor therapy

   Calcium (Ca ²⁺ ) is essential for mitochondrial homeostasis and function coordination, particularly in cancer cells that metabolize frequently to...

   Jun Wang, Wei Wang, ... Yongzhong Du in Journal of Nanobiotechnology

   Article Open access 19 September 2023
   

9. Natural L-type calcium channels antagonists from Chinese medicine

   L-type calcium channels (LTCCs), the largest subfamily of voltage-gated calcium channels (VGCCs), are the main channels for Ca ²⁺ influx during...

   Fangfang Xu, Wanna Cai, ... **aoqi Zhang in Chinese Medicine

   Article Open access 21 May 2024
   

10. Graphene oxide electrodes enable electrical stimulation of distinct calcium signalling in brain astrocytes

    Astrocytes are responsible for maintaining homoeostasis and cognitive functions through calcium signalling, a process that is altered in brain...

    Roberta Fabbri, Alessandra Scidà, ... Valentina Benfenati in Nature Nanotechnology

    Article Open access 10 July 2024
    

11. Regulation of Presynaptic Calcium Channels

    Voltage-gated calcium channels (VGCCs), especially Cav2.1 and Cav2.2, are the major mediators of Ca2+ influx at the presynaptic membrane in response...

    Pengyu Zong, Lixia Yue in Molecular Mechanisms of Neurotransmitter Release

    Chapter 2023
    

12. Sympathetic Nervous System Regulation of Cardiac Calcium Channels

    Calcium influx through voltage-gated calcium channels, Cav1.2, in cardiomyocytes initiates excitation-contraction coupling in the heart. The force...

    Pedro J. del Rivero Morfin, Steven O. Marx, Manu Ben-Johny in Voltage-gated Ca2+ Channels: Pharmacology, Modulation and their Role in Human Disease

    Chapter 2023
    

13. Upconverting-photon quenching-mediated perforation influx as an intracellular delivery method using posAuNP@UCNPs nanocomposites for osteoarthritis treatment

    Photoporation techniques based on plasmonic nanoparticles such as gold nanoparticles have been extensively studied for the intracellular delivery of...

    Hye ** Kim, Hui Bang Cho, ... Keun-Hong Park in Nano Convergence

    Article Open access 03 January 2024
    

14. Cytosolic Calcium Distribution and Thrombin Receptor Activation

    Since, receptor plays significant role in calcium signalling and to understand the mechanism of signalling in detail; an essential component is the...

    Ritu Agarwal, Sunil Dutt Purohit, Kritika in Modeling Calcium Signaling

    Chapter 2024
    

15. Acute cigarette smoke or extract exposure rapidly activates TRPA1-mediated calcium influx in primary human airway smooth muscle cells

    Tobacco smoking is the largest risk factor for develo** chronic obstructive pulmonary disease (COPD), and is associated with hyperresponsiveness of...

    **Heng Lin, Michael Taggart, ... Michael A. Gray in Scientific Reports

    Article Open access 05 May 2021
    

16. Myocardial TRPC6-mediated Zn²⁺ influx induces beneficial positive inotropy through β-adrenoceptors

    Baroreflex control of cardiac contraction (positive inotropy) through sympathetic nerve activation is important for cardiocirculatory homeostasis....

    Sayaka Oda, Kazuhiro Nishiyama, ... Motohiro Nishida in Nature Communications

    Article Open access 26 October 2022
    

17. Examining Mechanisms for Voltage-Sensitive Calcium Channel-Mediated Secretion Events in Bone Cells

    In addition to their well-described functions in cell excitability, voltage-sensitive calcium channels (VSCCs) serve a critical role in calcium (Ca ²⁺ )...

    Perla C. Reyes Fernandez, Christian S. Wright, ... William R. Thompson in Calcified Tissue International

    Article 01 June 2023
    

18. Roles and Sources of Calcium in Synaptic Exocytosis

    Calcium ions (Ca2+) play a critical role in triggering neurotransmitter release. The rate of release is directly related to the concentration of Ca2+...

    Zhao-Wen Wang, Sadaf Riaz, Longgang Niu in Molecular Mechanisms of Neurotransmitter Release

    Chapter 2023
    

19. Calcium signalling and transport in the kidney

    The kidney plays a pivotal role in regulating calcium levels within the body. Approximately 98% of the filtered calcium is reabsorbed in the nephron,...

    Alexander Staruschenko, R. Todd Alexander, ... Daria V. Ilatovskaya in Nature Reviews Nephrology

    Article 19 April 2024
    

20. Oligodendrocyte calcium signaling promotes actin-dependent myelin sheath extension

    Myelin is essential for rapid nerve signaling and is increasingly found to play important roles in learning and in diverse diseases of the CNS....

    Manasi Iyer, Husniye Kantarci, ... J. Bradley Zuchero in Nature Communications

    Article Open access 04 January 2024