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α-Linolenic Acid Induces Microglial Activation and Extracellular Tau Internalization
Neuroinflammation is the brain condition that occurs due to the hyper-activation of brain’s immune cells and microglia, over the stimulation of... -
Internalization and Endosomal Trafficking of Extracellular Tau in Microglia Improved by α-Linolenic Acid
Alzheimer’s disease (AD) is distinguished by extracellular accumulation of amyloid-beta plaques and intracellular neurofibrillary tangles of Tau.... -
Biochemical and Biophysical Characterization of Tau and α-Linolenic Acid Vesicles In Vitro
Alzheimer’s disease (AD) is characterized by the abnormal accumulation of disordered protein, that is, extracellular senile plaques of amyloid-β (Aβ)... -
Synthesis of New Multifunctional Linolenic Acid Vanillyl Ester and Investigation of Antioxidant and Antibacterial Activities
Vanillyl alcohol (VA) possesses potent antioxidant activity, yet its applicability is hindered by its limited solubility in emulsions or non-polar...
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Alpha-linolenic acid inhibits hepatocellular carcinoma cell growth through Farnesoid X receptor/β-catenin signaling pathway
BackgroundAltered lipid profiles are frequently present in cancer, and it is necessary to elucidate the role of changed lipid profiles in...
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γ-Linolenic acid in maternal milk drives cardiac metabolic maturation
Birth presents a metabolic challenge to cardiomyocytes as they reshape fuel preference from glucose to fatty acids for postnatal energy production
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Inhibitory Action of Omega-3 and Omega-6 Fatty Acids Alpha-Linolenic, Arachidonic and Linoleic acid on Human Erythrocyte Acetylcholinesterase
Acetylcholinesterase (AChE, E.C. 3.1.1.7) termed as the true cholinesterase functions to end cholinergic transmission at synapses. Due to its diverse...
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The Effects of Alpha Linolenic Acid (Omega-3 Fatty Acid) on Tobacco Craving Intensity, Withdrawal Symptoms and Biochemical Markers in Tobacco Users
Tobacco use causes serious public health concerns and causes many health problems like (asthma, COPD, stroke, cancer, etc.). While a number of...
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Improving linolenic acid content in rapeseed oil by overexpression of CsFAD2 and CsFAD3 genes
With the increasing public attention to the health benefit of polyunsaturated fatty acids (PUFAs) and demand for linolenic acid (C18:3), it is of...
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Determination of acrolein generation pathways from linoleic acid and linolenic acid: increment by photo irradiation
2-Propenal (acrolein) is a toxic aldehyde generated from the thermal degradation of edible oils. While previous studies have suggested that linolenic...
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Physaria fendleri FAD3-1 overexpression increases ɑ-linolenic acid content in Camelina sativa seeds
Camelina ( Camelina sativa ) is an oil crop with a short growing period, resistance to drought and cold, low fertilizer requirements, and can be...
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A low n-6/n-3 PUFA ratio and high level of dietary ɑ-linolenic acid improves sleep behavior in mice with insomnia
Camelina sativa oil (CSO) and Semen Ziziphi Spinosae oil (SZSO) are functional oils that have beneficial effects on brain health. This study...
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Gut microbiota-related metabolite alpha-linolenic acid mitigates intestinal inflammation induced by oral infection with Toxoplasma gondii
BackgroundOral infection with cysts is the main transmission route of Toxoplasma gondii ( T. gondii ), which leads to lethal intestinal inflammation....
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Alpha-linolenic acid modulates systemic and adipose tissue-specific insulin sensitivity, inflammation, and the endocannabinoid system in dairy cows
Metabolic disorders are often linked to alterations in insulin signaling. Omega-3 (n-3) fatty acids modulate immunometabolic responses; thus, we...
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Perilla oil and α-linolenic acid ameliorated thrombosis in rats induced by collagen and epinephrine
Perilla frutescens is an annual herbaceous plant widely cultivated for oil production in China, Japan, and Korea. In this study, we investigated the...
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Linoleic and linolenic acids reduce the effects of heat stress–induced damage in pig oocytes during maturation in vitro
Elevated environmental temperatures can induce heat stress which could reduce fertility and early embryonic development. Fatty acids can initiate an...
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Jasmonic Acid
Jasmonic acid (3-oxo-2-2′-cis-pentenyl-cyclopentane-1-acetic acid, abbreviated as JA) and its methyl ester (MeJA) and isoleucine conjugate (JA-Ile)... -
Dietary omega-3 polyunsaturated fatty acid and alpha-linolenic acid are associated with physical capacity measure but not muscle mass in older women 65–72 years
PurposeThe aim was to investigate the cross-sectional association of dietary omega-3 polyunsaturated fatty acids PUFA (alpha-linolenic acid (ALA),...
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Associations of Fatty Acid Profile with Abdominal Obesity in Men
The content of individual unsaturated fatty acids in blood plasma (measured by HPLC) and their association with abdominal obesity in a group of men...
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Increase in alpha-linolenic acid content by simultaneous expression of fatty acid metabolism genes in Sesame (Sesamum indicum L.)
Sesame is considered one of India’s important sources of edible oil and an excellent dietary source for its nutritional and medicinal value. Sesame DGAT1...