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  1. α-Linolenic Acid Induces Microglial Activation and Extracellular Tau Internalization

    Neuroinflammation is the brain condition that occurs due to the hyper-activation of brain’s immune cells and microglia, over the stimulation of...
    Smita Eknath Desale, Hariharakrishnan Chidambaram, Subashchandrabose Chinnathambi in Tau Protein
    Protocol 2024
  2. Internalization and Endosomal Trafficking of Extracellular Tau in Microglia Improved by α-Linolenic Acid

    Alzheimer’s disease (AD) is distinguished by extracellular accumulation of amyloid-beta plaques and intracellular neurofibrillary tangles of Tau....
    Smita Eknath Desale, Hariharakrishnan Chidambaram, ... Subashchandrabose Chinnathambi in Neuroprotection
    Protocol 2024
  3. Biochemical and Biophysical Characterization of Tau and α-Linolenic Acid Vesicles In Vitro

    Alzheimer’s disease (AD) is characterized by the abnormal accumulation of disordered protein, that is, extracellular senile plaques of amyloid-β (Aβ)...
    Smita Eknath Desale, Hariharakrishnan Chidambaram, Subashchandrabose Chinnathambi in Tau Protein
    Protocol 2024
  4. Synthesis of New Multifunctional Linolenic Acid Vanillyl Ester and Investigation of Antioxidant and Antibacterial Activities

    Vanillyl alcohol (VA) possesses potent antioxidant activity, yet its applicability is hindered by its limited solubility in emulsions or non-polar...

    Jennifer Indra Marvella, Hyung Kwoun Kim in Applied Biochemistry and Biotechnology
    Article 22 April 2024
  5. Alpha-linolenic acid inhibits hepatocellular carcinoma cell growth through Farnesoid X receptor/β-catenin signaling pathway

    Background

    Altered lipid profiles are frequently present in cancer, and it is necessary to elucidate the role of changed lipid profiles in...

    Shu Feng, **ngming **e, ... Haiyang Li in Nutrition & Metabolism
    Article Open access 23 August 2022
  6. γ-Linolenic acid in maternal milk drives cardiac metabolic maturation

    Birth presents a metabolic challenge to cardiomyocytes as they reshape fuel preference from glucose to fatty acids for postnatal energy production 1 , 2 ....

    Ana Paredes, Raquel Justo-Méndez, ... Mercedes Ricote in Nature
    Article 24 May 2023
  7. Inhibitory Action of Omega-3 and Omega-6 Fatty Acids Alpha-Linolenic, Arachidonic and Linoleic acid on Human Erythrocyte Acetylcholinesterase

    Acetylcholinesterase (AChE, E.C. 3.1.1.7) termed as the true cholinesterase functions to end cholinergic transmission at synapses. Due to its diverse...

    Mehmet Berk Akay, Kübra Şener, ... Ebru Bodur in The Protein Journal
    Article 20 December 2022
  8. The Effects of Alpha Linolenic Acid (Omega-3 Fatty Acid) on Tobacco Craving Intensity, Withdrawal Symptoms and Biochemical Markers in Tobacco Users

    Tobacco use causes serious public health concerns and causes many health problems like (asthma, COPD, stroke, cancer, etc.). While a number of...

    Anjali Singh, Narsingh Verma, ... Kshitij Bhardwaj in Indian Journal of Clinical Biochemistry
    Article 30 April 2024
  9. Improving linolenic acid content in rapeseed oil by overexpression of CsFAD2 and CsFAD3 genes

    With the increasing public attention to the health benefit of polyunsaturated fatty acids (PUFAs) and demand for linolenic acid (C18:3), it is of...

    Yunhao Liu, Zhuolin Du, ... Liang Guo in Molecular Breeding
    Article 29 January 2024
  10. Determination of acrolein generation pathways from linoleic acid and linolenic acid: increment by photo irradiation

    2-Propenal (acrolein) is a toxic aldehyde generated from the thermal degradation of edible oils. While previous studies have suggested that linolenic...

    Shunji Kato, Naoki Shimizu, ... Kiyotaka Nakagawa in npj Science of Food
    Article Open access 12 April 2022
  11. Physaria fendleri FAD3-1 overexpression increases ɑ-linolenic acid content in Camelina sativa seeds

    Camelina ( Camelina sativa ) is an oil crop with a short growing period, resistance to drought and cold, low fertilizer requirements, and can be...

    Mid-Eum Park, Hyun-A Choi, Hyun Uk Kim in Scientific Reports
    Article Open access 02 May 2023
  12. A low n-6/n-3 PUFA ratio and high level of dietary ɑ-linolenic acid improves sleep behavior in mice with insomnia

    Camelina sativa oil (CSO) and Semen Ziziphi Spinosae oil (SZSO) are functional oils that have beneficial effects on brain health. This study...

    Jie Zhu, Hua-nan Zhang, ... Shen Liang in Journal of Food Science and Technology
    Article 27 May 2024
  13. Gut microbiota-related metabolite alpha-linolenic acid mitigates intestinal inflammation induced by oral infection with Toxoplasma gondii

    Background

    Oral infection with cysts is the main transmission route of Toxoplasma gondii ( T. gondii ), which leads to lethal intestinal inflammation....

    **g Yang, Songhao Liu, ... Kangfeng Jiang in Microbiome
    Article Open access 12 December 2023
  14. Alpha-linolenic acid modulates systemic and adipose tissue-specific insulin sensitivity, inflammation, and the endocannabinoid system in dairy cows

    Metabolic disorders are often linked to alterations in insulin signaling. Omega-3 (n-3) fatty acids modulate immunometabolic responses; thus, we...

    Gitit Kra, Jayasimha Rayalu Daddam, ... Maya Zachut in Scientific Reports
    Article Open access 31 March 2023
  15. Perilla oil and α-linolenic acid ameliorated thrombosis in rats induced by collagen and epinephrine

    Perilla frutescens is an annual herbaceous plant widely cultivated for oil production in China, Japan, and Korea. In this study, we investigated the...

    ** Tae Kim, Seung Beom Lee, ... Hong ** Lee in Food Science and Biotechnology
    Article 25 January 2023
  16. Linoleic and linolenic acids reduce the effects of heat stress–induced damage in pig oocytes during maturation in vitro

    Elevated environmental temperatures can induce heat stress which could reduce fertility and early embryonic development. Fatty acids can initiate an...

    Jaelyn Z. Current, Miranda Mentler, Brian D. Whitaker in In Vitro Cellular & Developmental Biology - Animal
    Article 04 August 2022
  17. Jasmonic Acid

    Jasmonic acid (3-oxo-2-2′-cis-pentenyl-cyclopentane-1-acetic acid, abbreviated as JA) and its methyl ester (MeJA) and isoleucine conjugate (JA-Ile)...
    Satish C. Bhatla, Manju A. Lal in Plant Physiology, Development and Metabolism
    Chapter 2023
  18. Dietary omega-3 polyunsaturated fatty acid and alpha-linolenic acid are associated with physical capacity measure but not muscle mass in older women 65–72 years

    Purpose

    The aim was to investigate the cross-sectional association of dietary omega-3 polyunsaturated fatty acids PUFA (alpha-linolenic acid (ALA),...

    Masoud Isanejad, Behnam Tajik, ... Arja Erkkilä in European Journal of Nutrition
    Article Open access 16 December 2021
  19. Associations of Fatty Acid Profile with Abdominal Obesity in Men

    The content of individual unsaturated fatty acids in blood plasma (measured by HPLC) and their association with abdominal obesity in a group of men...

    V. S. Shramko, L. V. Shcherbakova, ... Yu. I. Ragino in Bulletin of Experimental Biology and Medicine
    Article 01 September 2023
  20. Increase in alpha-linolenic acid content by simultaneous expression of fatty acid metabolism genes in Sesame (Sesamum indicum L.)

    Sesame is considered one of India’s important sources of edible oil and an excellent dietary source for its nutritional and medicinal value. Sesame DGAT1...

    Muthulakshmi Chellamuthu, Kanimozhi Kumaresan, Selvi Subramanian in Physiology and Molecular Biology of Plants
    Article 22 March 2022
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