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Electrospun silk fibroin/fibrin vascular scaffold with superior mechanical properties and biocompatibility for applications in tissue engineering
Electrospun scaffolds play important roles in the fields of regenerative medicine and vascular tissue engineering. The aim of the research described...
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The application of composite scaffold materials based on decellularized vascular matrix in tissue engineering: a review
Decellularized vascular matrix is a natural polymeric biomaterial that comes from arteries or veins which are removed the cellular contents by...
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Silica nanoparticles enhance interfacial self-adherence of a multi-layered extracellular matrix scaffold for vascular tissue regeneration
PurposeBased on the clinical need for grafts for vascular tissue regeneration, our group developed a customizable scaffold derived from the human...
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Biomimetic vascular tissue engineering by decellularized scaffold and concurrent cyclic tensile and shear stresses
Decellularization by chemical approaches has harmful effects on extracellular matrix (ECM) proteins, and damages lots of functional peptides and...
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Fabrication Process of Triple-Layer Small-Diameter Vascular Scaffold with Microchannel Structure in the Inner Layer for Accelerated Endothelialization
Nowadays, many studies focus on the preparation of small-diameter vascular scaffolds, but some issues still existed that need to be urgently solved,...
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Scaffold Engineering with Flavone-Modified Biomimetic Architecture for Vascular Tissue Engineering Applications
Background:Vascular intimal hyperplasia (IH) is one of the key challenges in the clinical application of small-diameter vascular grafts. Current...
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Safety and efficacy of everolimus-eluting bioresorbable vascular scaffold for cardiac allograft vasculopathy (CART)
BackgroundCardiac allograft vasculopathy (CAV) is still the main drawback of heart transplantation (HTx) and percutaneous coronary intervention (PCI)...
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Fabrication of Endothelial Cell-Lining Polyurethane/Polycaprolactone Tubular Scaffold Coated with Conjugated Linoleic Acid for Small-Diameter Vascular Graft
Artificial vascular transplantation is one of the potential state-of-the-art therapies for cardiovascular diseases, which are known as a leading...
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Silica nanoparticles enhance the cyto- and hemocompatibility of a multilayered extracellular matrix scaffold for vascular tissue regeneration
PurposeThe limited availability of autologous vessels for vascular bypass surgeries is a major roadblock to treating severe cardiovascular diseases....
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Scaffold Materials and Toxicity
Toxicity of scaffolds is the inherent property of scaffold materials and hence it invites great attention in tissue engineering and other biomedical...
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Assessment of a Tissue-Engineered Vascular Graft Based on a Biodegradable Scaffold and Mesenchymal Stem Cells in a Long-Term Experiment In Vivo
AbstractA biodegradable tubular poly(L-lactide) scaffold and a method for seeding and culturing mesenchymal stem cells were developed to create a...
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Effect of Fluid Properties on Bone Scaffold Permeability
Good permeability of the scaffold is critical to allow for inflow of cells, nutrients, as well as for waste product transfer. However, during...
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3D bioprinted mesenchymal stem cell laden scaffold enhances subcutaneous vascularization for delivery of cell therapy
Subcutaneous delivery of cell therapy is an appealing minimally-invasive strategy for the treatment of various diseases. However, the subdermal site...
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Preclinical Evaluation of an Everolimus-Eluting Bioresorbable Vascular Scaffold Via a Long-Term Rabbit Iliac Artery Model
Background:Biodegradable poly (l-lactic acid) (PLLA), a bio safe polymer with a large elastic modulus, is widely used in biodegradable medical...
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On-Site Differentiation of Human Mesenchymal Stem Cells into Vascular Cells on Extracellular Matrix Scaffold Under Mechanical Stimulations for Vascular Tissue Engineering
Small-diameter vascular grafts are considered to be a promising strategy to treat late-stage vascular diseases, one of the largest causes of...
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Fabrication and optimization of bioactive cylindrical scaffold prepared by electrospinning for vascular tissue engineering
Vascular regeneration is strictly depended on the proliferation and spreading of the injured endothelial cell layer especially in the small diameter...
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In Vivo Evaluation of the Regenerative Capacity of a Nanofibrous, Prevascularized, Load-Bearing Scaffold for Bone Tissue Engineering
PurposeDue to the increasing number of orthopedic injuries occurring each year, there is a critical need for better treatment of improperly healed...
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Scaffold-Mediated Drug Delivery for Enhanced Wound Healing: A Review
Wound healing is a complex physiological process involving coordinated cellular and molecular events aimed at restoring tissue integrity. Acute...
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Three dimensional models of dedifferentiated liposarcoma cell lines: scaffold-based and scaffold-free approaches
Sarcomas are rare malignancies, the number of reports is limited, and this rarity makes further research difficult even though liposarcoma is one of...
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Flavor-switchable scaffold for cultured meat with enhanced aromatic properties
Cultured meat is emerging as a new type of food that can provide animal protein in a sustainable way. Many previous studies employed various types of...
