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Thermochemistry of amino-1,2,4-triazole derivatives
The present work is focused on determining the enthalpy of formation of several derivatives of amino-1,2,4-triazoles. Experimentally, the enthalpies...
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Synthesis of Betulin Conjugates and Its 1,2,3-Triazole Derivatives
AbstractThis review summarizes the main methods to introduce a triazole moiety into the structures of a pentacyclic triterpenoid betulin and its...
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Recent Advancements and Biological Activities of Triazole Derivatives: a Short Review
Many heterocyclic triazole rings and compounds containing triazole rings exhibit diverse biological activities. Heterocyclic derivatives of this...
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1,2,3-triazole derivatives as antiviral agents
In the last years, the emergence and spread of viral infections have been described with increased frequency and becomes a serious problem. The...
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Synthesis and Evaluation of Antibacterial Properties of 1,2,3-Triazole Sulfonamide Derivatives
AbstractObjective: Currently, microbial infections are a global threat to human health, and there is an urgent need to develop new and effective...
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Overview on Medicinal Impacts of 1,2,4-Triazole Derivatives
The nucleus 1,2,4-triazole is found in a wide variety of biologically active molecules. Interest in 1,2,4-triazole chemistry in recent decades has...
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Quinolone Tethered 1,2,3-Triazole Conjugates: Design, Synthesis, and Molecular Docking Studies of New Heterocycles as Potent Antimicrobial Agents
AbstractOur current work is aimed to synthesizing novel derivatives of 1,2,3-triazolyl-2-quinolone and applying docking studies and biological...
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Urease Inhibition Studies of New Benzimidazoles Containing Triazole Ring
AbstractA new series of benzimidazoles including triazole and thiosemicarbazide moieties was synthesized and their urease inhibition studies were...
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An insight on medicinal attributes of 1,2,3‐ and 1,2,4‐triazole derivatives as alpha-amylase and alpha-glucosidase inhibitors
Diabetes Mellitus (DM) is the globe’s common leading disease which is caused by high consumption of glucose. DM compiles groups of metabolic...
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Novel Thiazole–Triazole Hybrids: Synthesis, Characterization, and Antimicrobial Evaluation
AbstractPreviously unknown hybrid compounds comprising a thiazole and a triazole moieties were synthesized with excellent yields and characterized by...
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Synthesis, Spectral Analysis, and Insecticidal Activity of 1,2,3-Triazole Derivatives
AbstractA series of ( E )-5-{[(1 H -1,2,3-triazol-5-yl)sulfanyl]methyl}-4-(benzylideneamino)-4 H -1,2,4-triazole-3-thiols were synthesized using...
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Chemoinformatics Study of Benzodiazepine-1, 2, 3-triazole Derivatives Targeting Butyrylcholinesterase
This study aims to assess the potential bioactivity of newly designed benzodiazepine-1,2,3-triazole derivatives using in-silico methodologies, with a...
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Recent advances in triazole-benzenesulfonamide hybrids and their biological activities
Hybridization is the process of fusion of two or more existing moieties to make a single molecule. Triazoles and benzenesulfonamides are the useful...
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Synthesis of some novel 4-amino-4H-1,2,4-triazole-3-thiol derivatives
A novel series of pyrazolyl[1,2,4]triazoles has been synthesized by the reaction of polyfunctionalized-triazole 1 with symmetric and asymmetric β -dica...
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Textile Finishing Using Triazole Derivatives and Selenium Nanoparticles as an Anti-mosquito
Mosquito-repellent textiles are in high demand as a disease-prevention solution for mosquito bites as mosquito-borne diseases proliferate over the...
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Microwave-Assisted Synthesis, Molecular Docking, and Insecticidal Activity of 1,2,3-Triazole-Linked Chromone Derivatives
AbstractThe current study was carried out in an attempt to synthesize a new class of 1,2,3-triazole-linked hybrids by Cu(I)-catalyzed azide-alkyne...
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Expedient Synthesis of Coumarin–1,2,3-Triazole Hybrids via Click Chemistry and Their Antimicrobial Evaluation
AbstractThis study focuses on the synthesis of aromatic and heteroaromatic triazole derivatives known for their versatile therapeutic potential in...
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Inhibition of Liver Cancer Cell Viability by Triazole through Up-regulation of p38 Phosphorylation and Targeting the Activation of p-ERK1/2 and Akt Protein Expression
AbstractThe present study was aimed to explore the effect of triazole on growth and viability of liver cancer cells. Cell growth was examined using...
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Structural Characterization of a Porous 3D Cd(II) Coordination Polymer Based on 1,2,4-Triazole and 2-Nitro-4-Benzenedicarboxylic Acid
AbstractA new coordination polymer {[Cd 5 (triazole) 6 (nitro-bdc) 2 (DMF) 4 ] (DMF) 2 (H 2 O) 2 } n ( 1 ) (triazole = deprotoned 1,2,4-triazole, nitro-H 2 bdc =...
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Solvent-free reaction of 4-amino-1,2,4-triazole-3-thioles with 1,2,4-triazine-5-carbonitriles
A solvent-free reaction of 5-cyano-1,2,4-triazines with 4-amino-1,2,4-triazole-3-thiols was studied. The reactions take place only at elevated...