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Deltamethrin and transfluthrin select for distinct transcriptomic responses in the malaria vector Anopheles gambiae
BackgroundThe widespread use of pyrethroid insecticides in Africa has led to the development of strong resistance in Anopheles mosquitoes....
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Small-scale field evaluation of transfluthrin-treated eave ribbons and sandals for the control of malaria vectors in rural Tanzania
BackgroundEarly-evening and outdoor-biting mosquitoes may compromise the effectiveness of frontline malaria interventions, notably...
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Transfluthrin is Associated with High Susceptibility to Asthma in Children with Promoter Variants of Beta Chain of High-Affinity Receptor IgE and Tumour Necrosis Factors-α Genes
This study investigates the genetic variations in FcεR1β-109 C/T (rs512555) and TNF-α-308 G/A (rs1800629) genes and examines whether the mosquito...
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Transfluthrin eave-positioned targeted insecticide (EPTI) reduces human landing rate (HLR) of pyrethroid resistant and susceptible malaria vectors in a semi-field simulated peridomestic space
BackgroundVolatile pyrethroids (VPs) are proven to reduce human–vector contact for mosquito vectors. With increasing resistance to pyrethroids in...
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Semi-field evaluation of the exposure-free mosquito electrocuting trap and BG-Sentinel trap as an alternative to the human landing catch for measuring the efficacy of transfluthrin emanators against Aedes aegypti
BackgroundThe human landing catch (HLC) measures human exposure to mosquito bites and evaluates the efficacy of vector control tools. However, it may...
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Creating mosquito-free outdoor spaces using transfluthrin-treated chairs and ribbons
BackgroundResidents of malaria-endemic communities spend several hours outdoors performing different activities, e.g. cooking, story-telling or...
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Less is more: repellent-treated fabric strips as a substitute for full screening of open eave gaps for indoor and outdoor protection from malaria mosquito bites
BackgroundProviding protection from malaria vector bites, both indoors and outdoors, is crucial to curbing malaria parasite transmission. Screening...
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Human landing catches provide a useful measure of protective efficacy for the evaluation of volatile pyrethroid spatial repellents
BackgroundThe human landing catch (HLC) method, in which human volunteers collect mosquitoes that land on them before they can bite, is used to...
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Semi-field evaluation of freestanding transfluthrin passive emanators and the BG sentinel trap as a “push-pull control strategy” against Aedes aegypti mosquitoes
BackgroundSpatial repellents that drive mosquitoes away from treated areas, and odour-baited traps, that attract and kill mosquitoes, can be combined...
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Impact of a spatial repellent intervention on Anopheles kdr insecticide resistance allele in Sumba, Indonesia
BackgroundThe emergence of insecticide resistance and outdoor transmission in malaria-endemic areas underlines the urgent need to develop innovative...
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Protecting migratory farmers in rural Tanzania using eave ribbons treated with the spatial mosquito repellent, transfluthrin
BackgroundMany subsistence farmers in rural southeastern Tanzania regularly relocate to distant farms in river valleys to tend to crops for several...
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A randomized, double-blind placebo-control study assessing the protective efficacy of an odour-based ‘push–pull’ malaria vector control strategy in reducing human-vector contact
Novel malaria vector control strategies targeting the odour-orientation of mosquitoes during host-seeking, such as ‘attract-and-kill’ or...
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Evaluating human landing catches as a measure of mosquito biting and the importance of considering additional modes of action
Entomological evaluations of vector control tools often use human landing catches (HLCs) as a standard measure of a direct human-vector contact....
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Eave ribbons treated with transfluthrin can protect both users and non-users against malaria vectors
BackgroundEave ribbons treated with spatial repellents effectively prevent human exposure to outdoor-biting and indoor-biting malaria mosquitoes, and...
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Assessing the anti-resistance potential of public health vaporizer formulations and insecticide mixtures with pyrethroids using transgenic Drosophila lines
BackgroundInsecticide resistance—and especially pyrethroid resistance—is a major challenge for vector control in public health. The use of...
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The impact of transfluthrin on the spatial repellency of the primary malaria mosquito vectors in Vietnam: Anopheles dirus and Anopheles minimus
BackgroundThe complexity of mosquito-borne diseases poses a major challenge to global health efforts to mitigate their impact on people residing in...
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A new WHO bottle bioassay method to assess the susceptibility of mosquito vectors to public health insecticides: results from a WHO-coordinated multi-centre study
BackgroundThe continued spread of insecticide resistance in mosquito vectors of malaria and arboviral diseases may lead to operational failure of...
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Semi-field evaluation of the space spray efficacy of Fludora Co-Max EW against wild insecticide-resistant Aedes aegypti and Culex quinquefasciatus mosquito populations from Abidjan, Côte d’Ivoire
BackgroundSpace spraying of insecticides is still an important means of controlling Aedes and Culex mosquitoes and arboviral diseases. This study...
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The efficacy of insecticide-treated window screens and eaves against Anopheles mosquitoes: a sco** review
BackgroundFemale mosquitoes serve as vectors for a host of illnesses, including malaria, spread by the Plasmodium parasite. Despite monumental...
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Cunninghamella spp. produce mammalian-equivalent metabolites from fluorinated pyrethroid pesticides
Cunninghamella spp. are fungi that are routinely used to model the metabolism of drugs. In this paper we demonstrate that they can be employed to...