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Insights into Superinfection Immunity Regulation of Xanthomonas axonopodis Filamentous Bacteriophage cf
Filamentous bacteriophage cf infects Xanthomonas axonopodis pv. citri , a serious plant pathogen which causes citrus canker. To understand the...
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Prophages Preventing Phage Superinfection
One means by which prophages can modify bacterial phenotypes is by protecting lysogens from infections by additional phages. In part this protection...
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Analysis of PERV-C superinfection resistance using HA-tagged viruses
BackgroundUsing pigs as organ donors has advanced xenotransplantation to the point that it is almost ready for clinical use. However, there is still...
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Resurgence of SARS-CoV-2 Delta after Omicron variant superinfection in an immunocompromised pediatric patient
BackgroundPersistent SARS-CoV-2 infection in immunocompromised hosts is thought to contribute to viral evolution by facilitating long-term natural...
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Superinfection and the hypnozoite reservoir for Plasmodium vivax: a general framework
A characteristic of malaria in all its forms is the potential for superinfection (that is, multiple concurrent blood-stage infections). An additional...
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A hybrid transmission model for Plasmodium vivax accounting for superinfection, immunity and the hypnozoite reservoir
Malaria is a vector-borne disease that exacts a grave toll in the Global South. The epidemiology of Plasmodium vivax , the most geographically...
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Detection of SARS-CoV-2 intra-host recombination during superinfection with Alpha and Epsilon variants in New York City
Recombination is an evolutionary process by which many pathogens generate diversity and acquire novel functions. Although a common occurrence during...
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Acute hepatitis E virus superinfection increases mortality in patients with cirrhosis
BackgroundAlthough acute hepatitis E is not fatal in healthy individuals, it is unclear whether hepatitis E superinfection increases the mortality in...
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Superinfection associated with prolonged antibiotic use in non-ventilator associated hospital-acquired pneumonia
Background Non-ventilator associated hospital-acquired pneumonia accounts for significant antibiotic use and is associated with a high rate of...
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First come, first served: superinfection exclusion in Deformed wing virus is dependent upon sequence identity and not the order of virus acquisition
Deformed wing virus (DWV) is the most important globally distributed pathogen of honey bees and, when vectored by the ectoparasite Varroa destructor ,...
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Structural basis of superinfection exclusion by bacteriophage T4 Spackle
A bacterial cell infected with T4 phage rapidly establishes resistance against further infections by the same or closely related T-even-type...
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Mucormycosis Epidemic in Covid Era: A Sinister Superinfection
In this study, we attempt to look at the various presentations, comorbidities and association of the recent epidemic of rhino-orbital cerebral...
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Gastric mucosa-associated lymphoid tissue lymphoma in conjunction with multiple lymphomatous polyposis in the context of Helicobacter pylori and Helicobacter suis superinfection
A 53-year-old woman visited a doctor and complained of chest discomfort after meals. Esophagogastroduodenoscopy showed multiple granular elevations...
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Model of vaccine efficacy against HSV-2 superinfection of HSV-1 seropositive mice demonstrates protection by antibodies mediating cellular cytotoxicity
A majority of the world’s population is infected with HSV-1, highlighting the need for vaccines that are effective in HSV-1-seropositive hosts. We...
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Evaluation of the features of cystic echinococcosis with concurrent super-infection: a retrospective study in Southern Iran
ObjectiveSuperinfection of cystic echinococcosis (CE) is a life-threatening complication with significant morbidities, which can be prevented with...
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Effect of Broad-Spectrum Antibiotic De-escalation on Critically Ill Patient Outcomes: A Retrospective Cohort Study
PurposeAntibiotic de-escalation (ADE) in critically ill patients is controversial. Previous studies mainly focused on mortality; however, data are...
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Clostridium septicum infection complicating Hemolytic-Uremic Syndrome: a case report and review of the literature
Clostridium septicum ( C. septicum ) is a zoonotic bacillus found in 2.8% of healthy human stools. In humans, it can cause serious infections such as...
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An Eco-evolutionary Model on Surviving Lysogeny Through Grounding and Accumulation of Prophages
Temperate phages integrate into the bacterial genomes propagating along with the bacterial genomes. Multiple phage elements, representing diverse...
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Evaluating the performance of Plasmodium falciparum genetic metrics for inferring National Malaria Control Programme reported incidence in Senegal
BackgroundGenetic surveillance of the Plasmodium falciparum parasite shows great promise for hel** National Malaria Control Programmes (NMCPs)...
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Clinical spectrum and long-term outcomes of mpox: a cohort study spanning from acute infection to six-month follow-up
BackgroundCases of mpox have been reported worldwide since May 2022. Limited knowledge exists regarding the long-term course of this disease. To...