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Recommendations for robust and reproducible preclinical research in personalised medicine
BackgroundPersonalised medicine is a medical model that aims to provide tailor-made prevention and treatment strategies for defined groups of...
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Representations of personalised medicine in family medicine: a qualitative analysis
BackgroundThe promise of personalised medicine (PM) to transform healthcare has sparked great enthusiasm in the last years. Yet, its lack of...
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Forgetting how we ate: personalised nutrition and the strategic uses of history
Personalised nutrition (PN) has emerged over the past twenty years as a promising area of research in the postgenomic era and has been popularized as...
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A functional personalised oncology approach against metastatic colorectal cancer in matched patient derived organoids
Globally, colorectal cancer (CRC) is the third most frequently occurring cancer. Progression on to an advanced metastatic malignancy (metCRC) is...
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Perceptions of ‘Precision’ and ‘Personalised’ Medicine in Singapore and Associated Ethical Issues
Governments are investing in precision medicine (PM) with the aim of improving healthcare through the use of genomic analyses and data analytics to...
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Rapid triage for ischemic stroke: a machine learning-driven approach in the context of predictive, preventive and personalised medicine
BackgroundRecognising the early signs of ischemic stroke (IS) in emergency settings has been challenging. Machine learning (ML), a robust tool for...
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All around suboptimal health — a joint position paper of the Suboptimal Health Study Consortium and European Association for Predictive, Preventive and Personalised Medicine
First two decades of the twenty-first century are characterised by epidemics of non-communicable diseases such as many hundreds of millions of...
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Develo** tailored intervention strategies for implementation of stratified care to low back pain with physiotherapists in Nigeria: a Delphi study
BackgroundStratified care approach involving use of the STarT-Back tool to optimise care for patients with low back pain is gaining widespread...
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Personalized Medicine Beyond Stratification
Modern personalized medicine or precision medicine (PM) promises to take medical epistemology and evidence-based medicine a step further by...
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Personalised Prevention: Increasing or Decreasing Over-Medicalisation , Overdiagnosis and Overtreatment ?
The development of personalised prevention has been followed by rising concerns over over-medicalisation, overdiagnosis and overtreatment. Indeed, it...
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Guidance for the Harmonisation and Improvement of Economic Evaluations of Personalised Medicine
ObjectiveThe objective of this study was to develop guidance contributing to improved consistency and quality in economic evaluations of personalised...
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Future Role of Molecular Profiling in Small Breast Samples and Personalised Medicine
Molecular technologies for analysing clinical samples are develo** at a fast pace, with clinical trials now being designed around molecular tests,...
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Steps to Improve Precision Medicine in Epilepsy
Precision medicine is an old concept, but it is not widely applied across human health conditions as yet. Numerous attempts have been made to apply...
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Suboptimal Health and the Economic Impact to Healthcare from the Perspective of PPP Medicine
Suboptimal health status (SHS) is the physical state between health and disease, characterised by the self-reporting of general malaise and ambiguous...
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Diabetes precision medicine: plenty of potential, pitfalls and perils but not yet ready for prime time
Rapid advances in technology and data science have the potential to improve the precision of preventive and therapeutic interventions, and enable the...
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Targeted Therapy and Personalized Medicine
Targeted therapy and personalized medicine are novel emerging disciplines of cancer research intended for treatment and prevention. One of the most...
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“Different names for the same thing”? Novelty, expectations, and performative nominalism in personalized and precision medicine
This paper explores the complementary and contrasting uses of the terms ‘personalized medicine’ and ‘precision medicine’ in denotations of a...
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Economics and Precision Medicine
Introducing precision medicine strategies into routine practice will require robust economic evidence. Decision-makers need to understand the value...
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An apparent quandary: adoption of polygenics and gene panels for personalised breast cancer risk stratification
Over the past 30 years, genetic and epidemiological advances have revolutionised the prediction of breast cancer risk in women with significant...
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Stratified distribution of Th17 and Treg cells in patients with multi-stage rheumatoid arthritis
ObjectiveRheumatoid arthritis (RA) is a typical, progressive autoimmune disease. Its occurrence and development are associated with dysregulation of...
