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  1. Primary spindle cell tumor originating from the liver that was difficult to diagnose

    Background

    It has been reported that hepatocellular carcinoma (HCC) with spindle cell tumor accounts for 1.8% of all HCCs, but spindle cell tumors...

    Tomohiko Ikehara, Tadaaki Shimizu, ... Ataru Nakayama in Surgical Case Reports
    Article Open access 19 September 2022

  2. Mucinous tubular and spindle renal cell carcinoma revealed by a trauma of the kidney: a case report

    Background

    Mucinous tubular and spindle cell carcinoma is a rare renal tumor. It has been recognized as a distinct entity in the 2004 World Health...

    Kays Chaker, Mahdi Marrak, ... Yassine Nouira in Journal of Medical Case Reports
    Article Open access 12 July 2024

  3. Giant Cell Tumor

    Conventional giant cell tumor (GCT) is a benign but locally aggressive bone tumor composed of neoplastic component of mononuclear stromal cells and...
    Won-Jong Bahk in Diagnosis and Management of Primary Bone Tumors
    Chapter 2023

  4. A case of spindle and giant cell-type undifferentiated carcinoma of the extrahepatic bile duct

    Spindle and giant cell type undifferentiated carcinoma of the extrahepatic bile duct is an uncommon malignancy. We report a case involving the common...

    Keiji Nagata, Kojiro Nakamura, ... Takahisa Kyogoku in Clinical Journal of Gastroenterology
    Article 28 January 2024

  5. Mycobacterial Spindle Cell Pseudotumor of the Nasal Cavity

    Background

    Mycobacterial spindle cell pseudotumor (MSCP) represents an uncommon tumor-like proliferation associated with nontuberculous mycobacterial...

    Prokopios P. Argyris, Paul E. Wakely Jr in Head and Neck Pathology
    Article 07 April 2023

  6. Composite pheochromocytoma with spindle cell sarcoma — a rare tumor of the adrenal gland: case report

    Composite pheochromocytomas with a non-pheochromocytoma component stemming from an embryological origin other than the neural crest comprise a unique...

    Yigit Turk, Ziya Karimov, ... Ozer Makay in Hormones
    Article 18 March 2022

  7. Spindle function and Wnt pathway inhibition by PBX1 to suppress tumor progression via downregulating DCDC2 in colorectal cancer

    PBX1 is a transcription factor that regulates a variety of genes, involved in intracellular lipid metabolism, cell proliferation, and other pathways....

    Weigang Dai, Yinan Liu, ... Jianhui Chen in Oncogenesis
    Article Open access 04 February 2023

  8. Spindle Cell Sarcoma of the Maxilla: A Rare Entity, Case Report, and Review of the Literature

    Spindle cell sarcoma (SCS) is a malignancy, with the most recent Surveillance, Epidemiology, and End Results (SEER) data citing a total of 250...

    Sumeet Mahajan, Purushottam Chavan, ... P. Greeshma in Indian Journal of Otolaryngology and Head & Neck Surgery
    Article 13 July 2024

  9. Giant Cell Tumor of the Spine

    Giant cell tumor (GCT) of the spine is a rare condition characterized by locally aggressive osteolytic tumors. While GCTs commonly occur in the...
    Sebnem Orguc, Çağdaş Rıza Açar, Remide Arkun in Imaging of Primary Tumors of the Osseous Spine
    Chapter 2023

  10. Spindle Cell Tumors of the Sinonasal Tract: A Diagnostic Update with Focus on Ancillary Workup

    Spindle cell neoplasms arising in the head and neck may be challenging to recognize due to their relative rarity. While underlying molecular...

    Shahd S. Almohsen, Elizabeth G. Demicco in Head and Neck Pathology
    Article 16 February 2024

  11. Atypical spindle cell/pleomorphic lipomatous tumor with a sarcomatous component showing high mitotic activity and Ki-67 labeling index: report of a unique case mimicking dedifferentiated liposarcoma

    Atypical spindle cell/pleomorphic lipomatous tumor (ASPLT) is a new entity of benign adipocytic tumor that spans a wide spectrum of histology from...

    Shintaro Sugita, Taro Sugawara, ... Tadashi Hasegawa in Medical Molecular Morphology
    Article 02 July 2022

  12. A rare presentation of orbital spindle cell carcinoma a case report and brief review of the literature

    Background

    To describe a case of orbital spindle cell carcinoma which presented with limbal ischemia and briefly review the literature.

    ...
    Mansooreh Jamshidian Tehrani, Ali Rashidinia, ... Amirreza Esfandiari in BMC Ophthalmology
    Article Open access 08 September 2023

  13. E2F1 promotes cell cycle progression by stabilizing spindle fiber in colorectal cancer cells

    Background

    E2F1 is a transcription factor that regulates cell cycle progression. It is highly expressed in most cancer cells and activates...

    Zejun Fang, Min Lin, ... Chaoju Gong in Cellular & Molecular Biology Letters
    Article Open access 11 October 2022

  14. Protein Kinases Involved in Mitotic Spindle Checkpoint Regulation

    A number of checkpoint controls function to preserve the genome by restraining cell cycle progression until prerequisite events have been properly...
    Ingrid Hoffmann in Cell Cycle Regulation
    Chapter

  15. Intimal Sarcoma Versus Other Spindle Cell Neoplasms

    Intimal sarcomas are malignant mesenchymal neoplasms arising in large blood vessels of the systemic or pulmonary circulation and also within the...
    John M. Gross, Robert W. Ricciotti in Practical Lung Pathology
    Chapter 2022

  16. Granulation tissue-like spindle cell (sarcomatoid) carcinoma of the head and neck: a deceptively bland-looking underdiagnosed malignancy

    The diagnosis of head and neck spindle cell squamous carcinoma (SC-SCC) is often challenging. Lesions with a prominent inflammatory infiltrate and...

    Alessandro Franchi, Abbas Agaimy in Virchows Archiv
    Article Open access 26 February 2024

  17. Recurrent Ovarian Granulosa Cell Tumor

    Female patient, 58 years old, was admitted to the hospital with a pelvic mass found for 7 days, 4 years after chemotherapy after ovarian granulosa...
    Shuhui Zhao in MRI of Gynaecological Diseases
    Chapter 2023

  18. Spindle Cell Hemangioma

    Spindle cell hemangioma is a benign vascular tumor also known as spindle cell hemangioendothelioma.
    Simone Mocellin in Soft Tissue Tumors
    Chapter 2021

  19. Spindle Cells in Thyroid Aspirates

    Spindle cell lesions of the thyroid gland (T-SCLs) are uncommon conditions that encompass a wide spectrum of reactive, hyperplastic, and neoplastic...
    Shurong He, Xuedong Zhang, Aixia Hu in Thyroid FNA Cytology
    Chapter 2023

  20. A Low-grade Sinonasal Sarcoma Harboring EWSR1::BEND2: Expanding the Differential Diagnosis of Sinonasal Spindle Cell Neoplasms

    Background

    Molecular diagnostics has greatly refined sinonasal tumor pathology over the past decade. While much of the attention has focused on...

    Doreen N. Palsgrove, Varsha Manucha, ... Justin A. Bishop in Head and Neck Pathology
    Article 16 January 2023
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