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  1. Septic Shock

    Septic shock is a life-threatening condition resulting in the dysregulation of the host defense mechanisms in response to a pathogen. As its...
    Sacha Rozencwajg, Philippe Montravers in Textbook of Emergency General Surgery
    Chapter 2023
  2. Case report: septic shock after endometrial polypectomy with tissue removal system

    As an emerging surgical technology, tissue removal systems have been widely used in the treatment of endometrial polyps due to its characteristics of...

    Danna Su, Jiajie She, ... Ruiying Diao in BMC Women's Health
    Article Open access 23 October 2023
  3. Sepsis and Septic Shock

    This chapter outlines the essentials and most current concepts and understanding of the relevant epidemiology, definitions, pathogenesis, diagnosis...
    Mervyn Mer, Martin W. Dünser in Penetrating Trauma
    Chapter 2023
  4. Sepsis and Septic Shock

    Sepsis and septic shock are among the leading causes of admission to ICU. This chapter focuses on clinically relevant pathophysiology and its...
    Chapter 2023
  5. Impaired angiotensin II signaling in septic shock

    Recent years have seen a resurgence of interest for the renin–angiotensin–aldosterone system in critically ill patients. Emerging data suggest that...

    Adrien Picod, Bruno Garcia, ... Feriel Azibani in Annals of Intensive Care
    Article Open access 14 June 2024
  6. Septic Coagulopathy: Pathophysiology, Diagnosis, and Therapeutic Strategies

    Purpose of Review

    Septic coagulopathy is a complex disorder linked with multiple organ dysfunction and increased mortality, and definitive treatments...

    Toshiyuki Karumai, Yuki Kotani, ... Yoshiro Hayashi in Current Infectious Disease Reports
    Article 22 January 2024
  7. Precision Medicine in Septic Shock

    All patients with septic shock should be given the fundamental pillars of sepsis management (source control, antibiotic stewardship, initial...
    L. Chiscano-Camón, J. C. Ruiz-Rodriguez, R. Ferrer in Annual Update in Intensive Care and Emergency Medicine 2023
    Chapter 2023
  8. Septic Tanks as Small Municipal Sewage Treatment Plants

    The function of a septic tank is primarily to retain wastewater and purify it in an anaerobic process. Septic tanks are differentiated by flow rate...
    Conference paper 2023
  9. A model of porcine polymicrobial septic shock

    Background

    Sepsis is a life-threatening organ dysfunction caused by a dysregulated host response to infection. Mortality of patients with sepsis is...

    Finnja Marie Zurek-Leffers, Florian Lehmann, ... Nana-Maria Wagner in Intensive Care Medicine Experimental
    Article Open access 02 June 2023
  10. The role of endotoxin in septic shock

    Septic shock can be caused by a variety of mechanisms including direct effects of bacterial toxins such as endotoxin. Annually, approximately 5–7...

    John A. Kellum, Claudio Ronco in Critical Care
    Article Open access 19 October 2023
  11. Septic Shock, Tubular Necrosis, and Central Diabetes Insipidus: A Challenging Syndrome

    Background

    The association between septic shock, acute tubular necrosis, and central diabetes insipidus is infrequent: our recent clinical observation...

    Gabriele Melegari, Antonio Manenti, ... Alberto Barbieri in Intensive Care Research
    Article Open access 09 July 2024
  12. In Silico Modeling of Antibiotics Treatment Combined with Corticosteroids for Septic Arthritis

    Septic arthritis is a bacterial infection in the joint fluid and joint tissues. Although it is rare, septic arthritis is a serious condition—it can...
    Chapter 2024
  13. Whole blood transcriptomics identifies subclasses of pediatric septic shock

    Background

    Sepsis is a highly heterogeneous syndrome, which has hindered the development of effective therapies. This has prompted investigators to...

    Jamie O. Yang, Matt S. Zinter, ... Denise Villarreal-Chico in Critical Care
    Article Open access 08 December 2023
  14. Septic Arthritis

    Pediatric septic arthritis is a surgical emergency that requires multidisciplinary diagnosis and management. A high clinical suspicion with...
    Sreeharsha V. Nandyala, Martin J. Herman, Mininder S. Kocher in Pediatric Musculoskeletal Infections
    Chapter 2022
  15. Melatonin alleviates septic ARDS by inhibiting NCOA4-mediated ferritinophagy in alveolar macrophages

    Ferroptosis is a novel form of programmed cell death which can exacerbate lung injury in septic acute respiratory distress syndrome (ARDS). Alveolar...

    Wenting Xu, Yutong Wu, ... **n Lv in Cell Death Discovery
    Article Open access 24 May 2024
  16. Blockade of sympathetic ganglia improves vascular dysfunction in septic shock

    Sepsis/septic shock activates the sympathetic nervous system (SNS) to deal with the infection stress. However, an imbalanced or maladaptive response...

    Ana Maria Favero, Thiele Osvaldt Rosales, ... Jamil Assreuy in Naunyn-Schmiedeberg's Archives of Pharmacology
    Article 08 March 2024
  17. Assessment of hemodynamic dysfunction in septic newborns by functional echocardiography: a systematic review

    Background

    Neonatal sepsis remains a leading cause of mortality in neonatal units. Neonatologist-performed echocardiography (NPE) offers the potential...

    Flaminia Pugnaloni, Domenico Umberto De Rose, ... Cinzia Auriti in Pediatric Research
    Article 20 January 2024
  18. Carbapenem is not always the best choice in the treatment of septic shock

    Background

    Septic shock is a global public health burden. In addition to the improvement of the level of individual care, the improvement of the...

    Lu Wang, Xudong Ma, ... Zhenjie Hu in European Journal of Medical Research
    Article Open access 25 September 2023
  19. Inhibitory Activities of GDX-365 on HMGB1-mediated Septic Responses

    GDX-365, is the main fraction of black ginseng comprising protopanaxatriol-type rare ginsenosides (ginsenosides Rg3, Rk1, and Rg5). High mobility...

    Dong-Hyuk Baek, Go Oun Kim, ... Jong-Sup Bae in Biotechnology and Bioprocess Engineering
    Article 21 June 2023
  20. Diastolic/systolic blood pressure ratio for predicting febrile children with sepsis and progress to septic shock in the emergency department

    Objective

    Given the scarcity of studies analyzing the clinical predictors of pediatric septic cases that would progress to septic shock, this study...

    Chun-Ting Mu, Ying-Jui Lin, ... En-Pei Lee in BMC Emergency Medicine
    Article Open access 01 May 2024
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