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  1. Advances in biosynthesis of scopoletin

    Scopoletin is a typical example of coumarins, which can be produced in plants. Scopoletin acts as a precursor for pharmaceutical and health care...

    Bo-Tao He, Zhi-Hua Liu, ... Ying-** Yuan in Microbial Cell Factories
    Article Open access 02 August 2022
  2. Large-scale isolation of scopoletin from Nicotiana tabacum

    Nicotiana tabacum leaves are mainly used in the production of cigarettes and cigars all over the world, and a large amount of waste materials will be...

    Yujiao Chen, Min Chen, ... Guixue Wang in Biomass Conversion and Biorefinery
    Article 19 January 2023
  3. Cardioprotective Role of Scopoletin on Isoproterenol-Induced Myocardial Infarction in Rats

    Scopoletin is a phenolic coumarin isolated from a variety of plants and was originally used to treat various diseases including arthritis as well as...

    Ningning Rong, Ruyan Yang, ... Wenlong Zhang in Applied Biochemistry and Biotechnology
    Article 13 October 2022
  4. Scopoletin negatively regulates the HOG pathway and exerts antifungal activity against Botrytis cinerea by interfering with infection structures, cell wall, and cell membrane formation

    Botrytis cinerea is the causative agent of gray mold, a fungal disease affecting a broad array of food crops and resulting in considerable...

    **aojun Yuan, Fugen Yang, ... Qianqian Yang in Phytopathology Research
    Article Open access 02 January 2024
  5. Scopoletin mitigates maternal separation-induced anxiety-like and depression-like behaviors in male mice through modulation of the Sirt1/NF-κB pathway

    Rationale

    Early-life maternal separation can lead to anxiety-like and depression-like behaviors in mice reared under maternal separation conditions....

    Abdelrahim Alqudah, Esam Qnais, ... Taher Hatahet in Psychopharmacology
    Article 18 June 2024
  6. Scopoletin contents and antioxidant properties of some edible plants of Black Sea regions

    Scopoletin is a phytochemical of coumarins distributed in some plants. The aim of this study was the evaluation of scopoletin content and antioxidant...

    Damlanur Kübra Çakır, Oscar Zannou, Ilkay Koca in Discover Food
    Article Open access 02 February 2022
  7. Scopoletin alleviates high glucose-induced toxicity in human renal proximal tubular cells via inhibition of oxidative damage, epithelial-mesenchymal transition, and fibrogenesis

    Background

    Recent years of evidence suggest the crucial role of renal tubular cells in develo** diabetic kidney disease. Scopoletin (SCOP) is a...

    Sourav Kundu, Sitara Ghosh, Bidya Dhar Sahu in Molecular Biology Reports
    Article 06 May 2024
  8. Determining the effect of soil properties on the stability of scopoletin and its toxicity to target plants

    The sorption of the allelochemical scopoletin (7-hydroxy-6-methoxycoumarin) was studied in eight agricultural soils and different model sorbents. We...

    José Antonio Galán-Pérez, Beatriz Gámiz, Rafael Celis in Biology and Fertility of Soils
    Article 09 April 2021
  9. The phenylalanine ammonia-lyase gene McPAL3: the key gene involved in the scopoletin accumulation of Morinda citrifolia L.

    The relationship of the genes of PAL (phenylalanine ammonia-lyase) and scopoletin was explored to reveal the key gene involved in PAL activity, PAL ...

    Qingfen Wang, Juan Liu, ... Tian Wu in Brazilian Journal of Botany
    Article 02 June 2021
  10. In Silico Analysis of Scopoletin Interaction with Potential SARS-CoV-2 Target

    SARS-CoV-2 virus belongs to the family Coronaviridae, genus Betacoronavirus that appeared in late 2019 in Wuhan, China caused the historically...
    Tarik Ikanovic, Emir Sehercehajic, ... Rifat Hadziselimovic in New Technologies, Development and Application IV
    Conference paper 2021
  11. Exploring Scopoletin's Therapeutic Efficacy in DSS-Induced Ulcerative Colitis: Insights into Inflammatory Pathways, Immune Modulation, and Microbial Dynamics

    This study aimed to investigate the therapeutic potential of scopoletin in ulcerative colitis, with a primary focus on its impact on crucial...

    Abdelrahim Alqudah, Esam Qnais, ... Murtaza Tambuwala in Inflammation
    Article Open access 26 June 2024
  12. Validated simultaneous HPTLC analysis of scopoletin and gallic acid in the methanolic fraction of Jatropha glandulifera

    A high-performance thin-layer chromatography method for the simultaneous quantitative determination and validation of scopoletin and gallic acid in...

    Jyotsana Dwivedi, Abhishek Gupta, ... A. K. S. Rawat in JPC – Journal of Planar Chromatography – Modern TLC
    Article 01 October 2020
  13. Transcriptome responses of Arabidopsis to necrotrophic fungus Alternaria brassicae reveal pathways and candidate genes associated with resistance

    Alternaria leaf blight (ALB), caused by a necrotrophic fungus Alternaria brassicae is a serious disease of oleiferous Brassicas resulting in...

    S. Hamsa, Sivasubramanian Rajarammohan, ... Jagreet Kaur in Plant Molecular Biology
    Article 06 June 2024
  14. Enhanced accumulation of reduced glutathione by Scopoletin improves survivability of dopaminergic neurons in Parkinson’s model

    Parkinson’s disease (PD) is a neuromotor disorder, primarily manifested by motor anomalies due to progressive loss of dopaminergic neurons. Although...

    Priyadarshika Pradhan, Olivia Majhi, ... Devanjan Sinha in Cell Death & Disease
    Article Open access 10 September 2020
  15. Fluorescence of Scopoletin Including its Photoacidity and Large Stokes Shift

    Scopoletin is highly fluorescent in water and acts as a photoacid exhibiting excited-state proton transfer, ESPT, competitive with fluorescence. Its...

    Hunter T. Pham, Joy Yoo, ... Mark A. Muyskens in Journal of Fluorescence
    Article 24 December 2019
  16. Studien zur Qualitätskontrolle von Qinghao

    Qinghao, der getrocknete oberirdische Pflanzenteil von Artemisia annua L., wird seit etwa 2000 Jahren in China als TCM-Kräutermedizin eingesetzt. In...
    Chapter 2024
  17. Anti-ulcerogenic Properties of Sphaeralcea angustifolia on Gastric Ulcer in Mice

    Sphaeralcea angustifolia Cav. G. Don, Malvaceae, is a medicinal plant used to treat inflammatory and gastric diseases. Scopoletin, present in the...

    Jade Serrano-Román, Maribel Herrera-Ruiz, ... Pilar Nicasio-Torres in Revista Brasileira de Farmacognosia
    Article 11 May 2023
  18. A New Coumarin and Anti-Inflammatory Constituents from Polygonatum chingshuishanianum

    A new coumarin, methyl (E)-4-((6-methoxy-2-oxo-2H-chromen-7-yl)oxy)-2-methylbut-2-enoate ( 1 ), has been isolated from the rhizomes of Polygonatum...

    Chieh-Yang Cheng, Chien-Ming Huang, ... Jih-Jung Chen in Chemistry of Natural Compounds
    Article 13 September 2023
  19. Scopoletin ameliorates anxiety-like behaviors in complete Freund’s adjuvant-induced mouse model

    Anxiety disorder is highly prevalent worldwide and represents a chronic and functionally disabling condition, with high levels of psychological...

    Li Luo, Ting Sun, ... Qi Yang in Molecular Brain
    Article Open access 04 February 2020
  20. Specific features of epitope-MIPs and whole-protein MIPs as illustrated for AFP and RBD of SARS-CoV-2

    Molecularly imprinted polymer (MIP) nanofilms for alpha-fetoprotein (AFP) and the receptor binding domain (RBD) of the spike protein of SARS-CoV-2...

    **aorong Zhang, Aysu Yarman, ... Frieder W. Scheller in Microchimica Acta
    Article 04 April 2024
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