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Development and approval of rybelsus (oral semaglutide): ushering in a new era in peptide delivery
Achieving efficacious systemic levels of orally administered peptides is incredibly challenging due to the significant barriers to their...
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Effects of semaglutide-loaded lipid nanocapsules on metabolic dysfunction-associated steatotic liver disease
Metabolic dysfunction-associated steatotic liver disease (MASLD) is a highly prevalent chronic liver disease that can progress to end-stage...
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Elucidating the Degradation Pathways of Human Insulin in the Solid State
While there have been significant advances in the development of peptide oral dosage forms in recent years, highlighted by the clinical and...
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Medikamente zur Behandlung von Essstörungen und Adipositas
Indikationen, Wirkungsweise, Nebenwirkungen und Risiken, Kontraindikationen und Interaktionen werden für die Medikamente zur Behandlung von... -
Diabetes
Diabetes is a defect in sugar metabolism, along with resistance to insulin. Obesity is a significant factor. Diabetes must be carefully controlled in... -
Advanced Formulation Approaches for Proteins
Proteins and peptides are highly desirable as therapeutic agents, being highly potent and specific. However, there are myriad challenges with... -
Semaglutide and Tirzepatide reduce alcohol consumption in individuals with obesity
Alcohol Use Disorder (AUD) contributes significantly to global mortality. GLP-1 (Glucagon-like peptide-1) and GLP-1/GIP (Glucose-dependent...
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GLP-1 Receptor Agonist Exposures Are Increasingly Common and Generally Associated with Mild Symptoms: A Single Poison Center Experience
IntroductionGlucagon-like peptide-1 receptor agonist use has increased over the last decade for glycemic control in type 2 diabetes mellitus,...
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