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1. Retinal Pigment Epithelium and Choroid Transplantation

   This chapter discusses the surgical approach of retinal pigment epithelium (RPE)-choroidal patch transplantation for advanced age-related macular...

   Barbara Parolini, Michele Palmieri in Practical Manual of Vitreoretinal Surgery

   Chapter 2024
   

2. Giant retinal pigment epithelium tears with membranous nephropathy: a case report and literature review

   Background

   Kidney and eye diseases may be closely linked. Tears of the retinal pigment epithelium (RPE) have been reported to be related to kidney...

   Rui Dou, Yanhua Chu, ... Xue Bi in BMC Ophthalmology

   Article Open access 17 April 2024
   

3. The Retinal Pigment Epithelium: Cells That Know the Beat!

   The retinal pigment epithelium (RPE) ensures different functions crucial for photoreceptor survival, and thus for vision, such as photoreceptor outer...

   Elora M. Vanoni, Emeline F. Nandrot in Retinal Degenerative Diseases XIX

   Conference paper 2023
   

4. Serous maculopathy with absence of retinal pigment epithelium (SMARPE) associated with large drusen

   Purpose

   To describe the association of serous maculopathy with absence of retinal pigment epithelium (SMARPE) and large drusen in patients with...

   Luiz H. Lima, João Pedro Romero Braga, ... Rodrigo Jorge in International Journal of Retina and Vitreous

   Article Open access 22 January 2024
   

5. Oxidative Stress-Involved Mitophagy of Retinal Pigment Epithelium and Retinal Degenerative Diseases

   The retinal pigment epithelium (RPE) is a highly specialized and polarized epithelial cell layer that plays an important role in sustaining the...

   Si-Ming Zhang, Bin Fan, ... Guang-Yu Li in Cellular and Molecular Neurobiology

   Article Open access 01 July 2023
   

6. The mouse retinal pigment epithelium mounts an innate immune defense response following retinal detachment

   The retinal pigment epithelium (RPE) maintains photoreceptor viability and function, completes the visual cycle, and forms the outer blood-retinal...

   Steven F. Abcouwer, Bruna Miglioranza Scavuzzi, ... David N Zacks in Journal of Neuroinflammation

   Article Open access 25 March 2024
   

7. Common clinical features of unilateral retinal pigment epithelium dysgenesis and combined hamartoma of the retina and retinal pigment epithelium

   Background

   Herein, we report two cases of unilateral retinal pigment epithelium dysgenesis (URPED) in Chinese patients and explore the relationship...

   Zhe Zhu, Jun **ao, ... Chenchen Zhang in BMC Ophthalmology

   Article Open access 15 January 2022
   

8. Regulation of epithelial-mesenchymal transition in retinal pigment epithelium and its associated cellular signaling cascades: an updated review

   Background

   The epithelial-mesenchymal transition (EMT) affects the retinal pigment epithelium's natural homeostasis. According to observations from...

   Brijesh Gelat, Pooja Malaviya, ... Rahul Gelat in Beni-Suef University Journal of Basic and Applied Sciences

   Article Open access 26 October 2023
   

9. PEDF protects retinal pigment epithelium from ferroptosis and ameliorates dry AMD-like pathology in a murine model

   Age-related macular degeneration (AMD) is the leading cause of irreversible vision damage among elderly individuals. There is still no efficient...

   Wei **ang, Longhui Li, ... Kunbei Lai in GeroScience

   Article 28 December 2023
   

10. Metabolic fingerprinting on retinal pigment epithelium thickness for individualized risk stratification of type 2 diabetes mellitus

    The retina is an important target organ of diabetes mellitus, with increasing evidence from patients and animal models suggesting that retinal...

    Shaopeng Yang, Zhuoting Zhu, ... Wei Wang in Nature Communications

    Article Open access 18 October 2023
    

11. Management of Combined Hamartoma of the Retina and Retinal Pigment Epithelium in Children

    Combined hamartoma of the retina and the retinal pigment epithelium (CHRRPE) is a congenital benign proliferation of the retinal pigment epithelium,...

    Sofía M. Muns, Victor M. Villegas, Timothy G. Murray in Pediatric Vitreoretinal Surgery

    Chapter 2023
    

12. Tumors of the Retinal Pigment Epithelium

    Tumors of the retinal pigment epithelium (RPE), although relatively uncommon, can be mistaken for choroidal melanoma and are of importance to the...

    Kevin K. Ma, Daniel M. Albert, Lucy H. Young in Albert and Jakobiec's Principles and Practice of Ophthalmology

    Reference work entry 2022
    

13. Conservatism and Variability of the Antioxidant Defense System in the Retinal Pigment Epithelium of Vertebrates

    Abstract

    During evolution and adaptation to life conditions, organisms have developed the strategies allowing them to use reactive oxygen species...

    Yu. V. Markitantova, V. N. Simirskii in Journal of Evolutionary Biochemistry and Physiology

    Article 01 May 2023
    

14. Cilia-associated wound repair mediated by IFT88 in retinal pigment epithelium

    Primary cilia are conserved organelles that integrate extracellular cues into intracellular signals and are critical for diverse processes, including...

    Ke Ning, Mohajeet B. Bhuckory, ... Yang Sun in Scientific Reports

    Article Open access 21 May 2023
    

15. Comparative 3D genome analysis between neural retina and retinal pigment epithelium reveals differential cis-regulatory interactions at retinal disease loci

    Background

    Vision depends on the interplay between photoreceptor cells of the neural retina and the underlying retinal pigment epithelium (RPE). Most...

    Eva D’haene, Víctor López-Soriano, ... Elfride De Baere in Genome Biology

    Article Open access 17 May 2024
    

16. Gene Therapy Activates Retinal Pigment Epithelium Cell Proliferation for Age-related Macular Degeneration in a Mouse Model

    Objective

    Age-related macular degeneration (AMD) is a degenerative retinal disease. The degeneration or death of retinal pigment epithelium (RPE)...

    Yun Yuan, Wen Kong, ... Guo-hua Shi in Current Medical Science

    Article 17 March 2023

17. Transcriptomic and proteomic retinal pigment epithelium signatures of age-related macular degeneration

    There are currently no treatments for geographic atrophy, the advanced form of age-related macular degeneration. Hence, innovative studies are needed...

    Anne Senabouth, Maciej Daniszewski, ... Alice Pébay in Nature Communications

    Article Open access 26 July 2022
    

18. Generation and characterization of retinal pigment epithelium from patient iPSC line to model oculocutaneous albinism (OCA)1A disease

    Oculocutaneous albinism (OCA) is characterized by reduced melanin biosynthesis affecting the retina, thus impairing visual function. The disease...

    Janavi Subramani, Niharika Patlolla, ... Rajarshi Pal in Journal of Biosciences

    Article 20 January 2024
    

19. Sub-retinal pigment epithelium tubules in non-neovascular age-related macular degeneration

    To describe a novel optical coherence tomography (OCT) signature resembling sub-retinal pigment epithelium (RPE) tubules (SRT) in non-neovascular...

    Serena Fragiotta, Mariacristina Parravano, ... Giuseppe Querques in Scientific Reports

    Article Open access 07 September 2022
    

20. CRISPR/Cas9 mediated specific ablation of vegfa in retinal pigment epithelium efficiently regresses choroidal neovascularization

    The CRISPR/Cas9 system easily edits target genes in various organisms and is used to treat human diseases. In most therapeutic CRISPR studies,...

    **kyu Park, Gang Cui, ... Suk Ho Byeon in Scientific Reports

    Article Open access 06 March 2023