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1. A Simple HPLC–UV Approach for Rapid Enantioseparation of Cathinones, Pyrovalerones and Other Novel Psychoactive Substances on a 2.5-µm Cellulose Tris-(3,5-dimethylphenyl-carbamate) Column

   The misuse of so called novel psychoactive substances is still a challenging problem worldwide. A special attribute of a lot of these compounds is a...

   Johannes S. Hägele, Elisabeth Seibert, Martin G. Schmid in Chromatographia

   Article Open access 30 January 2020
   

2. Comparative neuropharmacological studies on three pyrrolidine-containing synthetic cathinones

   Purpose

   3,4-Methylenedioxypyrovalerone (3,4-MDPV) is a prevalent member of α-pyrrolidinophenones, a group of new psychoactive substances, known for...

   Jakub Wojcieszak, Dariusz Andrzejczak, ... Jolanta B. Zawilska in Forensic Toxicology

   Article Open access 01 February 2020
   

3. Four Synthetic Cathinones: 3-Chloromethcathinone, 4-Chloromethcathinone, 4-Fluoro-α-Pyrrolidinopentiophenone, and 4-Methoxy-α-Pyrrolidinopentiophenone Produce Changes in the Spontaneous Locomotor Activity and Motor Performance in Mice with Varied Profiles

   Two chloromethcathinones, 3-chloromethcathinone (3-CMC) and 4-chloromethcathinone (4-CMC), and two para -substituted α-pyrrolidinophenones,...

   Jakub Wojcieszak, Katarzyna Kuczyńska, Jolanta B. Zawilska in Neurotoxicity Research

   Article Open access 06 June 2020
   

4. MDPV (3,4-methylenedioxypyrovalerone) administered to mice during development of the central nervous system produces persistent learning and memory impairments

   Background

   Synthetic cathinones (SC) constitute the second most frequently abused class of new psychoactive substances. They serve as an alternative...

   Katarzyna Kuczyńska, Katarzyna Bartkowska, ... Jakub Wojcieszak in Pharmacological Reports

   Article Open access 09 May 2024
   

5. Cytotoxicity of α-Pyrrolidinophenones: an Impact of α-Aliphatic Side-chain Length and Changes in the Plasma Membrane Fluidity

   Pyrovalerone derivatives (α-pyrrolidinophenones) form a branch of synthetic cathinones, a second most prominent group of novel psychoactive...

   Jakub Wojcieszak, Dariusz Andrzejczak, ... Jolanta B. Zawilska in Neurotoxicity Research

   Article Open access 27 June 2018
   

6. Virtual ‘Experiential Expert’ Communities of Practice in Sharing Evidence-Based Prevention of Novel Psychoactive Substance (NPS) Use: the Portuguese Experience

   We present findings from a unique virtual community of practice piloted to support a programme of prevention evidence and knowledge sharing among...

   Susana Henriques, Marie Claire Van Hout, António Teixeira in International Journal of Mental Health and Addiction

   Article 20 July 2020
   

7. Effects of the new generation α-pyrrolidinophenones on spontaneous locomotor activities in mice, and on extracellular dopamine and serotonin levels in the mouse striatum

   Purpose

   Pyrovalerone derivatives (α-pyrrolidinophenones) form a distinct branch of synthetic cathinones, a popular group of novel psychoactive...

   Jakub Wojcieszak, Dariusz Andrzejczak, ... Jolanta B. Zawilska in Forensic Toxicology

   Article Open access 26 February 2018
   

8. Acute Intoxications Involving α-Pyrrolidinobutiophenone (α-PBP): Results from the Swedish STRIDA Project

   Introduction

   Many new psychoactive substances (NPS) introduced as recreational drugs have been associated with severe intoxication and death.

   ...

   Lisa Franzén, Matilda Bäckberg, ... Anders Helander in Journal of Medical Toxicology

   Article Open access 19 June 2018
   

9. Synthetic Cathinones: Neurotoxic Health Hazards and Potential for Abuse

   Synthetic cathinonesSynthetic cathinones (SCs) represent an alternative to the prevailing array of drugs of abuse, with this being attributable to...

   Trevor Archer, Richard M. Kostrzewa in Synthetic Cathinones

   Chapter 2018
   

10. Cytotoxic Activity of Pyrovalerone Derivatives, an Emerging Group of Psychostimulant Designer Cathinones

    The growing popularity of novel psychoactive substances (NPS) has aroused the concerns of public health specialists. The pyrovalerone derivatives are...

    Jakub Wojcieszak, Dariusz Andrzejczak, ... Jolanta B. Zawilska in Neurotoxicity Research

    Article 13 June 2016
    

11. Synthetic Cathinones—Prevalence and Motivations for Use

    This chapter considers the prevalencePrevalence of and motivationsMotivations for use of synthetic cathinonesSynthetic cathinones . As part of the...

    John M. Corkery, Amira Guirguis, ... Fabrizio Schifano in Synthetic Cathinones

    Chapter 2018
    

12. α-Pyrrolidinophenones: a new wave of designer cathinones

    Recent years have witnessed a rapid increase in the number and prevalence of novel psychoactive substances (NPSs). Among them, pyrovalerone...

    Jolanta B. Zawilska, Jakub Wojcieszak in Forensic Toxicology

    Article 25 January 2017
    

13. New psychoactive substances: an overview on recent publications on their toxicodynamics and toxicokinetics

    This review article covers English-written and PubMed-listed review articles and original studies published between January 2015 and April 2016...

    Markus R. Meyer in Archives of Toxicology

    Article 24 September 2016
    

14. Structure-Activity Relationships of Synthetic Cathinones

    Until recently, there was rather little interest in the structure-activity relationships (SARs) of cathinone analogs because so few agents were...

    Richard A. Glennon, Małgorzata Dukat in Neuropharmacology of New Psychoactive Substances (NPS)

    Chapter 2016
    

15. In vitro cytochrome P450 inhibition potential of methylenedioxy-derived designer drugs studied with a two-cocktail approach

    In vitro cytochrome P450 (CYP) inhibition assays are common approaches for testing the inhibition potential of drugs for predicting potential...

    Julia Dinger, Markus R. Meyer, Hans H. Maurer in Archives of Toxicology

    Article 23 November 2014