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Defining a Workspace Without Singular Configurations of 3-PRRS Type Tripod
3-PRRS tripod type parallel manipulator is formed by connecting the moving and fixed platforms through three legs of PRRS type, where P, R, and S...
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The WUR0000125 PRRS resilience SNP had no apparent effect on pigs’ infectivity and susceptibility in a novel transmission trial
BackgroundPorcine reproductive and respiratory syndrome (PRRS) remains one of the most important infectious diseases for the pig industry. A novel...
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Technical considerations towards commercialization of porcine respiratory and reproductive syndrome (PRRS) virus resistant pigs
The selection and introduction of disease resistance genes in livestock not only provide health benefits to animals but opportunities for breeders...
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Inverse Kinematics and Workspace of a 3-PRRS Type Parallel Manipulator
In this paper, methods of workspace analysis of a 3-PRRS type parallel manipulator are described. The equations of spheres and circles on these...
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The efficacy and performance impact of Fostera PRRS in a Vietnamese commercial pig farm naturally challenged by a highly pathogenic PRRS virus
Highly pathogenic porcine reproductive and respiratory syndrome virus (HP-PRRSV) is characterized by high fever, respiratory distress, and high...
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The natural compound Sanggenon C inhibits PRRSV infection by regulating the TRAF2/NF-κB signalling pathway
Porcine reproductive and respiratory syndrome (PRRS) is a serious infectious disease and one of the major causes of death in the global pig industry....
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Toll-like receptor 7 and RIG-I-like receptors expression in peripheral blood mononuclear cells of naïve patients with hepatitis C
BackgroundThe proper function of Pattern Recognition Receptors (PRRs) as a part of the host immune system can eliminate numerous pathogens from the...
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Pattern Recognition Beyond the Surface: Soluble Pattern Recognition and Their Role in Periodontitis
Purpose of ReviewPattern recognition receptors (PRRs) are important mediators of tissue homeostasis. Soluble forms of PRRs, including a novel group...
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The C-terminal proline-rich repeats of Enteropathogenic E. coli effector EspF are sufficient for the depletion of tight junction membrane proteins and interactions with early and recycling endosomes
BackgroundEnteropathogenic E. coli (EPEC) causes acute infantile diarrhea accounting for significant morbidity and mortality in develo**...
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PAMPs of the Fungal Cell Wall and Mammalian PRRs
Fungi are opportunistic pathogens that infect immunocompromised patients and are responsible for an estimated 1.5 million deaths every year. The...
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High production of IL-12 by human dendritic cells stimulated with combinations of pattern-recognition receptor agonists
The cytokine IL-12p70 is crucial for T helper 1 (Th1) polarization and the generation of type 1 immunity required to fight cancer and pathogens....
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The contribution of pattern recognition receptor signalling in the development of age related macular degeneration: the role of toll-like-receptors and the NLRP3-inflammasome
Age-related macular degeneration (AMD) is a leading cause of irreversible vision loss, characterised by the dysfunction and death of the...
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Biomedical knowledge graph construction of Sus scrofa and its application in anti-PRRSV traditional Chinese medicine discovery
As a new data management paradigm, knowledge graphs can integrate multiple data sources and achieve quick responses, reasoning and better predictions...
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Ursonic acid from medicinal herbs inhibits PRRSV replication through activation of the innate immune response by targeting the phosphatase PTPN1
Porcine reproductive and respiratory syndrome (PRRS), caused by the PRRS virus (PRRSV), has caused substantial economic losses to the global swine...
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Engineered polysaccharides for controlling innate and adaptive immune responses
Therapeutic interventions can be designed by exploiting the immune system’s ability to initiate specific responses to various stimuli. However,...
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Detection and Quantification of Cryptococcus Uptake by Phagocytic Cells Using Imaging Flow Cytometry
Cryptococcus neoformans, the predominant etiological agent of cryptococcosis, is an encapsulated fungal pathogen found ubiquitously in the...
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Pattern-Triggered Immunity and Effector-Triggered Immunity: crosstalk and cooperation of PRR and NLR-mediated plant defense pathways during host–pathogen interactions
The elucidation of the molecular basis underlying plant-pathogen interactions is imperative for the development of sustainable resistance strategies...
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Geometry and Inverse Kinematics of 3-PRRS Type Parallel Manipulator
In this paper the methods of structural synthesis and inverse kinematics of 3-PRRS type parallel manipulator (PM) are developed. This PM is formed...
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Automated Tail Bound Analysis for Probabilistic Recurrence Relations
Probabilistic recurrence relations (PRRs) are a standard formalism for describing the runtime of a randomized algorithm. Given a PRR and a time limit...
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Effect of vaccination route (intradermal vs. intramuscular) against porcine reproductive and respiratory syndrome using a modified live vaccine on systemic and mucosal immune response and virus transmission in pigs
BackgroundPorcine reproductive and respiratory syndrome (PRRS) is a viral disease with worldwide distribution and an enormous economic impact. To...
