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A bivalent porcine circovirus type 2 (PCV2), PCV2a-PCV2b, vaccine offers biologically superior protection compared to monovalent PCV2 vaccines
Recent publications suggest PCV2 vaccine-induced protection is superior when the vaccine and challenge are closely matched. PCV2’s evolutionary rate,...
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Molecular genotypic analysis of porcine circovirus type 2 reveals the predominance of PCV2d in Vietnam (2018–2020) and the association between PCV2h, the recombinant forms, and Vietnamese vaccines
We conducted nucleotide and amino acid sequence alignment and phylogenetic analysis of porcine circovirus ORF2 (Cap protein) from 17 PCV2-positive...
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Rapid detection of porcine circovirus type 2 by a red latex microsphere immunochromatographic strip
AbstractTo establish a rapid and specific antigen detection method for porcine circovirus type 2 (PCV2), monoclonal antibodies (mAbs) were produced...
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Virome of wild rats (Rattus norvegicus) captured far from pig farms in Jiangsu province of China reveals novel porcine circovirus type 2d (PCV2d) sequences
BackgroundPorcine circovirus type 2 (PCV2) has caused great economic losses in the global pig industry. There have been published records of wild...
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Mutation of the sixth amino acid of the Rep protein has no effect on porcine circovirus 2b but enhances porcine circovirus 2d replication in vitro
Porcine circovirus type 2 (PCV2) is the etiological agent of post-weaning multisystemic wasting syndrome (PMWS). The original prevalent genotype,...
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Genetic and phylogenetic analysis of porcine circovirus type 2 on Jeju Island, South Korea, 2019–2020: evidence of a novel intergenotypic recombinant
Porcine circovirus type 2 (PCV2) is the most ubiquitous viral pathogen of pigs and has persistently affected the global swine industry. Since first...
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Discriminating the eight genotypes of the porcine circovirus type 2 with TaqMan-based real-time PCR
BackgroundThe porcine circovirus type 2 (PCV2) is divided into eight genotypes including the previously described genotypes PCV2a to PCV2f and the...
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Porcine circovirus type 2 (PCV2) infection in Hebei Province from 2016 to 2019: a retrospective study
Porcine circovirus type 2 (PCV2) is the primary causative agent of porcine circovirus-associated diseases in swine, the most common of which are...
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Porcine circovirus type 2 (PCV2) genoty** in Austrian pigs in the years 2002 to 2017
BackgroundEight different PCV2 genotypes with varying prevalence and clinical impact have been described so far. PCV2 infection is still widespread...
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Development of recombinant capsid protein-based single serum dilution ELISA for sero-detection of porcine circovirus type 2 infection in pigs
Porcine Circovirus 2 (PCV2) is the major causative agent of postweaning multisystemic wasting syndrome (PMWS) of swine and is one of the reasons for...
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Genetic diversity and different cross-neutralization capability of porcine circovirus type 2 isolates recently circulating in South Korea
BackgroundPorcine circovirus type 2 (PCV2) is a small single-stranded DNA virus and a primary cause of PCV-associated diseases (PCVAD) that result...
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Molecular basis for the different PCV2 susceptibility of T-lymphoblasts in Landrace and Piétrain pigs
Clinically, Landrace pigs are more susceptible to porcine circovirus-associated diseases (PCVADs) than Piétrain pigs. We previously found that...
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The first isolation of porcine circovirus type 2e from a Korean pig
This study describes the first isolation and genetic characterization of the newly emerging porcine circovirus type 2e (PCV2e) from Korean pigs. The...
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Detection of porcine circovirus 2, porcine parvovirus 1, and torque teno sus virus k2a in wild boars from northeastern Patagonia, Argentina
Wild boars can act as a reservoir of pathogenic viruses that affect the pig industry. Here, we assessed the presence of porcine circovirus 2, porcine...
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Co-circulation and genetic characteristics of porcine circoviruses in postweaning multisystemic wasting syndrome cases in commercial swine farms
This study aimed to investigate the co-infection and genetic characteristics of Porcine circoviruses in PMWS-affected pigs in five commercial...
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Molecular characterization and phylogenetic analysis of porcine circovirus 2 from Kerala, India
Porcine circovirus type 2 (PCV2), the causative agent of porcine circovirus-associated diseases (PCVADs), has a worldwide distribution, and is...
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A prospective CSFV-PCV2 bivalent vaccine effectively protects against classical swine fever virus and porcine circovirus type 2 dual challenge and prevents horizontal transmission
Classical swine fever virus (CSFV) infection leading to CSF outbreaks is among the most devastating swine diseases in the pig industry. Porcine...
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Molecular epidemiology and genetic variation analyses of porcine circovirus type 2 isolated from Yunnan Province in China from 2016-2019
BackgroundPorcine circovirus type 2 (PCV2) is the causative agent of porcine circovirus-associated disease (PCVAD). Its prevalence in swine herds was...
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Isolation and pathogenicity of porcine circovirus type 2 in mice from Guangxi province, China
BackgroundPorcine circovirus type 2 (PCV2), a member of the genus Circovirus and family Circoviridae , is a closed, small, circular, and...