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Delineating genetic inheritance and nonallelic genic interactions for grain iron and zinc concentration, yield and its attributes by generation mean analysis in pearl millet [Pennisetum glaucum (L.) R. Br.]
Pearl millet is a major staple cereal crop worldwide and genetic biofortification with enhanced grain iron (Fe) and zinc (Zn) concentrations are...
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Interloci CNV Interactions in Variability of the Phenotypes of Neurodevelopmental Disorders
AbstractMost copy number variations (CNV) of pathogenetic significance are associated with neurodevelopmental phenotypes and characterized by...
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The interactions between interleukin-1 family genes: IL1A, IL1B, IL1RN, and obesity parameters
BackgroundObesity has been recognized as a worldwide growing problem, producing many pathologies including the promotion of “proinflammatory state.”...
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Deciphering higher order non-allelic interactions for quantitative characters through twelve generation mean analysis in castor (Ricinus communis L.)
The genetic architecture of oil content, seed yield and its related biometric traits in castor was investigated through generation mean analysis in...
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Detection of Allele-Specific 3D Chromatin Interactions Using High-Resolution In-Nucleus 4C-seq
Chromosome conformation capture techniques are a set of methods used to determine 3D genome organization through the capture and identification of... -
QTL epistasis plays a role of homeostasis on heading date in rice
If there was no gene interaction, the gene aggregation effect would increase infinitely with the increase of gene number. Epistasis avoids the...
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Search for Epistatically Interacting Genetic Variants That Are Associated with Vasovagal Syncope within Biallelic Combinations
AbstractThe most common cause of transient loss of consciousness is vasovagal syncope (VVS), which occurs owing to hypoperfusion of the brain due to...
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Recent Approaches in Breeding for Salt Tolerance in Rice in Bangladesh
Salinity is one of the most important abiotic stresses which limit agricultural productivity and pose threats to food security in Bangladesh as rice... -
Genetic Analysis of the 1000-Grain Weight Trait in Interlinear Hybrids of Winter Rye (Secale cereale L.)
AbstractThe aim of the study is to quantify the contribution of additive, dominant, and epistatic dispersions to the overall genetic variation of the...
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Increased mutation and gene conversion within human segmental duplications
Single-nucleotide variants (SNVs) in segmental duplications (SDs) have not been systematically assessed because of the limitations of map**...
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Genetic analysis of maydis leaf blight resistance in subtropical maize (Zea mays L.) germplasm
Knowledge on the genetics of maydis leaf blight (MLB) is crucial to breed the resistant maize cultivars to combat disease epidemics as a sustainable...
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A Methodological Workflow to Analyze Synthetic Lethality and Drug Synergism in Cancer Cells
Current concepts in treating cancer usually neglect individual tumor characteristics such as a given mutational make up. Consequently, a... -
New genetic and epigenetic insights into the chemokine system: the latest discoveries aiding progression toward precision medicine
Over the past thirty years, the importance of chemokines and their seven-transmembrane G protein-coupled receptors (GPCRs) has been increasingly...
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Molecular mechanisms and topological consequences of drastic chromosomal rearrangements of muntjac deer
Muntjac deer have experienced drastic karyotype changes during their speciation, making it an ideal model for studying mechanisms and functional...
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Genetic estimation of grain yield and its attributes in three wheat (Triticum aestivum L.) crosses using six parameter model
Grain yield is a complex polygenic trait representing a multiplicative end product of contributing yield attributes governed by simple to complex...
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Transferability of Nikita and Sukkula retrotransposons in domestic goose (Anser anser domesticus) genome
This article aimed to detect the existence of barley-specific Nikita and Sukkula retrotransposons in domestic geese samples and to evaluate the...
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Phenotypic Overlap of 22q11.2 Microduplication and Noonan Syndrome in a Fetus with Increased NT, Facial Dysmorphism, and Narrow Pulmonary Trunk
22q11.2 deletion syndrome is a common microdeletion syndrome with a prevalence of 1 in 2000-6000 live births. Clinical features include conotruncal...
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Transposable Elements: Emerging Therapeutic Targets in Neurodegenerative Diseases
Neurodegenerative diseases, such as Alzheimer’s disease (AD), Parkinson’s disease (PD), and amyotrophic lateral sclerosis (ALS), are characterized by...
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Dynamic analysis of QTLs on plant height with single segment substitution lines in rice
Dynamic regulation of QTLs remains mysterious. Single segment substitution lines (SSSLs) and conditional QTL map** and functional QTL map**s are...
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Biotic Stress Resistance in Vigna mungo and Vigna radiata: A Molecular Perspective
Mungbean and blackgram are the two important legumes widely cultivated in the Asian continent for grain, vegetable, green manure, and fodder. Both...