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Nicotinamide riboside restores nicotinamide adenine dinucleotide levels and alleviates brain injury by inhibiting oxidative stress and neuroinflammation in a mouse model of intracerebral hemorrhage
Hemorrhagic stroke is a global health problem owing to its high morbidity and mortality rates. Nicotinamide riboside is an important precursor of...
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Nicotinamide Riboside Supplementation Restores Myocardial Nicotinamide Adenine Dinucleotide Levels, Improves Survival, and Promotes Protective Environment Post Myocardial Infarction
AimsMyocardial infarction (MI) is a major cause of death. Nicotinamide adenine dinucleotide (NAD + ) is a coenzyme in oxidative phosphorylation and...
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Nicotinamide adenine dinucleotide metabolism and arterial stiffness after long-term nicotinamide mononucleotide supplementation: a randomized, double-blind, placebo-controlled trial
Many animal studies have shown that oral administration of the nicotinamide adenine dinucleotide (NAD + ) precursor nicotinamide mononucleotide (NMN)...
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The complexity of nicotinamide adenine dinucleotide (NAD), hypoxic, and aryl hydrocarbon receptor cell signaling in chronic kidney disease
Early-stage detection of chronic kidney diseases (CKD) is important to treatment that may slow and occasionally halt CKD progression. CKD of diverse...
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Chronic nicotinamide mononucleotide supplementation elevates blood nicotinamide adenine dinucleotide levels and alters muscle function in healthy older men
Preclinical studies have revealed that the elevation of nicotinamide adenine dinucleotide (NAD + ) upon the administration of nicotinamide...
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Nicotinamide adenine dinucleotide (NAD+) reduction enabled by an atomically precise Au-Ag alloy nanocluster
The redox property of the ultrasmall coinage nanoclusters (with several to tens of Au/Ag atoms) has elucidated the electron-transfer capacity of...
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Nicotinamide adenine dinucleotide reduced (NADH) is a natural UV filter of certain bird lens
In this work, we for the first time report the identification of UV filters in the bird eye lens. We found that lenses of some raptors (black kite,...
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Stabilization and quantitative measurement of nicotinamide adenine dinucleotide in human whole blood using dried blood spot sampling
Nicotinamide adenine dinucleotide (NAD + ) is a coenzyme essential for energy production. Recently, associations between NAD + and aging-related...
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The state of association of the Na+-translocating reduced nicotinamide adenine dinucleotide:quinone oxidoreductase in detergent solution – an ultracentrifugation study
Na+:reduced nicotinamide adenine dinucleotide:quinone reductase (Na+ -NQR) is a redox-driven sodium pump found in some bacterial respiratory chains.... -
Reduced nicotinamide adenine dinucleotide phosphate in redox balance and diseases: a friend or foe?
The nicotinamide adenine dinucleotide (NAD + /NADH) and nicotinamide adenine dinucleotide phosphate (NADP + /NADPH) redox couples function as cofactors...
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Two Photon Fluorescence Lifetime Imaging of Reduced Nicotinamide Adenine Dinucleotide in Brain Research
Current understanding of the structure and functions of the brain is inadequate to explain the complex neurobiological phenomenon associated with the... -
Nicotinamide mononucleotide, a potential future treatment in ocular diseases
PurposeThe burden of ocular diseases has been gradually increasing worldwide. Various factors are suggested for the development and progression of...
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NAD+ Precursors Nicotinamide Mononucleotide (NMN) and Nicotinamide Riboside (NR): Potential Dietary Contribution to Health
Purpose of ReviewNAD+ is a vital molecule that takes part as a redox cofactor in several metabolic reactions besides being used as a substrate in...
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NR-SAFE: a randomized, double-blind safety trial of high dose nicotinamide riboside in Parkinson’s disease
Nicotinamide adenine dinucleotide (NAD) replenishment therapy using nicotinamide riboside (NR) shows promise for Parkinson’s disease (PD) and other...
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Nicotinamide Mononucleotide and Nicotinamide Riboside Reverse Ovarian Aging in Rats Via Rebalancing Mitochondrial Fission and Fusion Mechanisms
PurposeThis study examined the effects of nicotinamide mononucleotide (NMN) and nicotinamide riboside (NR) on folliculogenesis and mitochondrial...
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Prophylactic nicotinamide treatment protects from rotenone-induced neurodegeneration by increasing mitochondrial content and volume
Leber’s hereditary optic neuropathy (LHON) is driven by mtDNA mutations affecting Complex I presenting as progressive retinal ganglion cell...
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Nicotinamide mononucleotide supplementation mitigates osteopenia induced by modeled microgravity in rats
Exposure to weightlessness causes severe osteopenia, resulting in raised fracture risk. The current study aimed to investigate whether nicotinamide...
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Purification of Angiotensin-Converting Enzyme (ACE) from Sheep Kidney and Inhibition Effect of Reduced Nicotinamide Adenine Dinucleotide (NADH) on Purified ACE Activity
Angiotensin-converting enzyme (ACE, EC 3.4.15.1) is a significant enzyme that regulates blood pressure. ACE inhibitors are often used in the...