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1. Neuroprotection Method and Protocols

   This volume contains cutting-edge molecular biology methods on neuroprotective mechanisms and specific preclinical models of the CNS injury, iseases...

   Swapan K. Ray in Methods in Molecular Biology

   Book 2024
   

2. An intestinal sphingolipid confers intergenerational neuroprotection

   In animals, maternal diet and environment can influence the health of offspring. Whether and how maternal dietary choice impacts the nervous system...

   Wenyue Wang, Tessa Sherry, ... Roger Pocock in Nature Cell Biology

   Article Open access 03 August 2023
   

3. Relaxation of mitochondrial hyperfusion in the diabetic retina via N6-furfuryladenosine confers neuroprotection regardless of glycaemic status

   The recovery of mitochondrial quality control (MQC) may bring innovative solutions for neuroprotection, while imposing a significant challenge given...

   Aidan Anderson, Nada Alfahad, ... Jose R. Hombrebueno in Nature Communications

   Article Open access 06 February 2024
   

4. Adenosine A2A Receptor-Containing Heteromers and Neuroprotection

   Adenosine is a nucleoside with key functions in cell metabolism and in the regulation of several physiological processes in mammals. Its actions are...

   Rafael Franco, Rafael Rivas-Santisteban, ... Irene Reyes-Resina in Purinergic Signaling in Neurodevelopment, Neuroinflammation and Neurodegeneration

   Chapter 2023
   

5. Molecular targets of histone deacetylase inhibitors in neurodegeneration and neuroprotection

   Background

   Neurodegenerative diseases show various phenotypes of molecular and cellular malfunction including mitochondrial dysfunction and...

   Yeongwon Park, Shangfei Yu, ... Hyemyung Seo in Molecular & Cellular Toxicology

   Article 17 April 2024
   

6. The atypical antidepressant tianeptine confers neuroprotection against oxygen–glucose deprivation

   Proregenerative and neuroprotective effects of antidepressants are an important topic of inquiry in neuropsychiatric research. Oxygen–glucose...

   Burcu Ersoy, Marie-Louise Herzog, ... Karen Gertz in European Archives of Psychiatry and Clinical Neuroscience

   Article Open access 01 September 2023
   

7. Enhanced mitochondrial biogenesis promotes neuroprotection in human pluripotent stem cell derived retinal ganglion cells

   Mitochondrial dysfunctions are widely afflicted in central nervous system (CNS) disorders with minimal understanding on how to improve mitochondrial...

   Michelle Surma, Kavitha Anbarasu, ... Arupratan Das in Communications Biology

   Article Open access 24 February 2023
   

8. Recent advances to Neuroprotection: repurposing drugs against neuroinflammatory disorders

   Cell death is a natural mechanism for biological clearance for the maintenance of homeostasis in a dynamic microenvironment of the central nervous...

   Wishah Bilal, Muhammad Babar Khawar, ... Fareeha Qamar in Molecular Biology Reports

   Article 25 May 2023
   

9. Inhibition of OGFOD1 by FG4592 confers neuroprotection by activating unfolded protein response and autophagy after ischemic stroke

   Background

   Acute ischemic stroke is a common neurological disease with a significant financial burden but lacks effective drugs. Hypoxia-inducible...

   Jian **e, Yuan Zhang, ... Zhijun Zhang in Journal of Translational Medicine

   Article Open access 07 March 2024
   

10. Morphine Induced Neuroprotection in Ischemic Stroke by Activating Autophagy Via mTOR-Independent Activation of the JNK1/2 Pathway

    Morphine (Mor) has exhibited efficacy in safeguarding neurons against ischemic injuries by simulating ischemic/hypoxic preconditioning (I/HPC)....

    Wenying Chi, Yaru Huang, ... Fanjun Meng in Neurochemical Research

    Article 05 June 2024
    

11. Pro-survival Phenotype of HIF-1α: Neuroprotection Through Inflammatory Mechanisms

    Hypoxia-inducible factor 1 (HIF-1) is a major player in the oxygen sensor system as well as a transcription factor. HIF-1 is also associated in the...

    Michelle A. Puchowicz, Kehkashan Parveen, ... Joseph LaManna in Oxygen Transport to Tissue XLIV

    Conference paper 2023
    

12. Neuroprotection in Subarachnoid Hemorrhage

    All cases of subarachnoid hemorrhage, in the absence of treatment, can eventually cause secondary brain injury. Metabolic or biochemical events lead...

    Arunabha Karmakar, Yasir M. Abdelwahid, Gustav Strandvik in Management of Subarachnoid Hemorrhage

    Chapter 2022
    

13. Adenosine receptor A1 enhanced mitochondrial biogenesis and exerted neuroprotection after cerebral ischemia through PGC-1α

    Ischemic stroke is a common cause of morbidity and mortality worldwide. The current treatment fails to achieve satisfactory results, because...

    Wei Han, Erfei Zhang, ... Yahui Chen in Experimental Brain Research

    Article 20 April 2023
    

14. Drug Synergism as the Basis of Rational Neuroprotection

    Optimization of the choice of neuroprotective therapy regimens in patients with cerebrovascular diseases (CVD), taking into account the synergism of...

    M. V. Putilina, N. V. Teplova in Neuroscience and Behavioral Physiology

    Article 01 October 2022

15. Transcriptomics and Metabolomics Unveil the Neuroprotection Mechanism of AnGong NiuHuang (AGNH) Pill Against Ischaemic Stroke Injury

    As a famous prescription in China, AnGong NiuHuang (AGNH) pill exerts good neuroprotection for ischaemic stroke (IS), but its mechanism is still...

    Liangliang Tian, Guangzhao Cao, ... **g**g Zhang in Molecular Neurobiology

    Article 24 February 2024
    

16. Neuroprotection by acrolein sequestration through exogenously applied scavengers and endogenous enzymatic enabling strategies in mouse EAE model

    We have previously shown that the pro-oxidative aldehyde acrolein is a critical factor in MS pathology. In this study, we found that the acrolein...

    Jonathan Tang, Anna Alford, ... Riyi Shi in Scientific Reports

    Article Open access 12 March 2024
    

17. Single-atom cobalt nanozymes promote spinal cord injury recovery by anti-oxidation and neuroprotection

    Oxidative stress and inflammation are central pathophysiological processes in a traumatic spinal cord injury (SCI). Antioxidant therapies that reduce...

    Yuxing Jiang, Hongtao Rong, ... Hao Wang in Nano Research

    Article 13 March 2023
    

18. Role of Amyloid Beta in Neurodegeneration and Therapeutic Strategies for Neuroprotection

    The gradual loss of neurons’ structure and function in the central nervous system is known as neurodegeneration. It is a defining feature of several...

    Priyam Ghosh, Kavita Narang, Parameswar Krishnan Iyer in Neuroprotection

    Protocol 2024
    

19. A potential primary endpoint for clinical trials in glaucoma neuroprotection

    The purpose of this retrospective, longitudinal study is to evaluate the relationship between MD slope from visual field tests collected over a short...

    Carlos Gustavo De Moraes, Keith J. Lane, ... Jeffrey M. Liebmann in Scientific Reports

    Article Open access 02 May 2023
    

20. Tangeretin confers neuroprotection, cognitive and memory enhancement in global cerebral ischemia in rats

    Global cerebral ischemia is commonly associated with neurological deficits, including cognitive and memory impairments. The present study aims to...

    Narayanarao Alla, Sujatha Palatheeya, ... Ramakrishna Kakarla in 3 Biotech

    Article 08 December 2023